Use of zolpidem 10 mg as a benzodiazepine substitute in 84 patients with insomnia

Human Psychopharmacology

Volumn 13, Issue 8, 1998, Pages 551-559

  Allain, H ^a,d   Le Coz, F ^b   Borderies, P ^c   Schuck, S ^a   De La Giclais, B ^c   Patat, A ^b   Gandon, J M ^b  

^a UNIVERSITÉ DE RENNES 1   (France)

^b Biotrial SA   (France)

^c SANOFI   (France)

^d Institute of Electronics and Telecommunicalions of Rennes   (France)

Author keywords

Hypnotics; Insomnia; Sleep; Triazolam; Withdrawal; Zolpidem

Indexed keywords

BENZODIAZEPINE RECEPTOR STIMULATING AGENT; HYPNOTIC SEDATIVE AGENT; TRIAZOLAM; ZOLPIDEM;

ADULT; AGED; ALERTNESS; ANXIETY; AROUSAL; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG TOLERANCE; HUMAN; INSOMNIA; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NIGHTMARE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; WAKEFULNESS; WITHDRAWAL SYNDROME;

EID: 0032409146     PISSN: 08856222     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1077(1998120)13:8<551::AID-HUP31>3.0.CO;2-V     Document Type: Article

References (50)

1. Adams, K. and Oswald, L. (1989). Can a rapidly-eliminated hypnotic cause daytime anxiety? Pharmacopsychiatry, 22, 115-119.
2. Allain, H. (1990). Insomnie et benzodiazépines: questions actuelles. Psychol. A Med., 22, 947-961.
3. Allain, H., Delahaye, C. Le Coz, F., Guilleminault, C., Blin. P., Decombe, R. and Martinet, J. P. (1991). Post-marketing surveillance of zopiclone in insomnia: analysis of 20,513 cases. Sleep, 14, 408-413.
4. American Psychiatric Association (1990). Benzodiazepines, Dependency, Toxicity and Abuse. APA, Washington.
5. Anonymous (1984). Drugs and insomnia: the use of medications to promote sleep. JAMA, 251, 2410-2414.
6. 3H] zolpidem binding in the rat brain: an imidazopyridine with agonist properties at central benzodiazepine receptors. Europ. J. Pharmacol., 130, 257-261.
7. Balter, M. B., Manheimer, D. J., Mellinger, G. D. and Uhlenhuth, E. H. (1984). A cross-national comparison of anti-anxiety/sedative drug use. Curr. Med. Resp. Opin., 8 (suppl. 4), 5-20.
8. Barnas, C., Fleischhacker, W., Stuppäck, C., Whiteworth, A. B. and Hinterhuber, H. (1988). Investigation of benzodiazepine-consumers concerning intake habits, signs of abuse or dependence and information about drug. Pharmacopsychiatry, 21, 355-356.
9. Begaud, B. (1989). La pharmacodépendance aux benzodiazépines. Psychol. Med., 21A, 185-195.
10. Bianchi, M. and Musch, B. (1990). Zopiclone discontinuation: review of 25 studies assessing withdrawal and rebound insomnia. Int. Clin. Psychopharmacol., 5(suppl. 2), 139-145.
11. Bixler, E. O., Kales, J. D. and Kales, A. (1985). Rebound insomnia and elimination half-life: assessment of individual subject response. J. Clin. Pharmacol., 25, 115-124.
12. Blanchard, J. C., Boireau, A. and Julou, L. (1983). Brain receptors and zopiclone. Pharmacology, 27 (Suppl. 2), 242-247.
13. Bourin, M. (1987). La dédependance aux benzodiazépines. Mythe ou réalité? La Lettre du Pharmacologue, 1, 62-66.
14. Boyer, P. (1989). Durée de traitement et stratégie d'arrêt. Psychol. Med., 21, 157-162.
15. Busto, U., Sellers, E., Naranjo, C., Cappel, H., Sanchez-Craig, M. and Sykora, K. N. (1986). Withdrawal reaction after long-term therapeutic use of benzodiazepines. N. Engl. J. Med., 315, 854-859.
16. Clift, A. (1972). Factors leading to dependence on hypnotic drugs. Br. Med. J., 3, 614-617.
17. Dunbar, G. C., Perera, M. H. and Jenner, F. A. (1989). Patterns of benzodiazepine use in Great Britain as measured by a general population survey. Br. J. Psychiatry, 155, 836-841.
18. Fyer, A., Liebowitz, M., German, J. M., Campeas, R. and Klein, D. (1987). Discontinuation of alprazolam treatment in panic patients. Am. J. Psychiatry, 144, 303-398.
19. Garma, L., Widldcher, D. and Scherrer, J. (1982). Traitement de l'insomnie et sevrage des hypnotiques. Sem. Hôp., 58, 2441-2449.
20. George, C. and Robertson, D. (1987). Clinical consequences of abrupt drug withdrawal. Med. Toxicol., 2, 367-382.
21. Gillin, J., Spinweber, C. and Johnson, L. (1989). Rebound of insomnia: a critical review. J. Clin. Psychopharmacol., 9, 161-172.
22. Greenblatt, D., Harmatz, J., Zinny, M. and Shader, R. (1987). Effect of gradual withdrawal on the rebound sleep disorder after discontinuation of triazolam. N. Engl. J. Med., 317, 722-728.
23. Hanin, B. and Marks, J. (1988). Dependance aux benzodiazépines et syndrome de sevrage. Revue de la littérature. Psychiatr. Psychobiol., 3, 347-364.
24. Hanin, B. and Marks, J. (1989). Dépendance aux benzodiépines et contrat thérapeutique. Neuro-Psy, 4, 455-459.
25. Kales, A., Scharf, M. B., Kales, J. D. and Soldates, C. R. (1979). Rebound of insomnia: a potential hazard following withdrawal of certain benzodiazepines. JAMA, 241, 1692-1695.
26. Kales, A., Blixter, E., Soldates, C., Vela-Bueno, A., Jacoby, J. and Kales, J. (1982). Quazepam and flurazepam: long term use and extended withdrawal. Clin. Pharmacol. Ther., 32, 781-788.
27. Kales, A., Soldates, C. R., Bixler, E. O. and Kales J. D. (1983). Rebound insomnia and rebound anxiety: a review. Pharmacology, 26, 121-137.
28. Lader, M. (1984). The rational use of anxiolytics. International Medicine, 4, 23-26.
29. Lader, M. (1987). Benzodiazepine dependence. Pharmacology, 1, 299-547.
30. Langer, S. Z., Arbilla, S., Scatton, B., Niddam, R. and Dubols, A. (1988). Receptors involved in the mechanism of action of zolpidem. Imidazopyridine in Sleep Disorders, Sauvanet, J. P., Langer, S. Z. and Morselli, P. L. (Eds), Raven Press, New York, pp. 55-70.
31. Lemoine, P. (1992). Le sevrage des hypnotiques. Application à la zopiclone. In Zopiclone, 1987-1992: 5 Années de Pratique Clinique, Grivols, H. et al. (Eds) Elsevier, Paris, pp. 137-152.
32. Marks, J. (1978). The Benzodiazepines. Use, Overuse, Misuse, Abuse. MPT Press, Lancaster.
33. Monti, J.-M. (1989). Effect of zolpidem on sleep in insomniac patients. Eur. J. Clin. Pharmacol., 36, 461-466.
34. Monti, J. M., Attali, P., Monti, D., Zipfel, A., de la Giclais, B. and Morselli, P. L. (1994). Zolpidem and rebound insomnia - A double blind, controlled polysomnographic study in chronic insomniac patients. Pharmaco-Psychiatry, 27, 166-175.
35. Murphy, S. M., Owen, R. T. and Tyrer, P. J. (1984). Withdrawal symptoms after six weeks' treatment with diazepam. Lancet, 11, 1389.
36. Nguyen, J. M., Allain, H., Martinet, J. P., Bénéton, C., Reymanm, J. M. and Décombe, R. (1991). Les anxiolytiques et les hypnotiques et Bretagne: une étude pharmacoépidémiologique. Ann. Med. Int., 142, 163-167.
37. Nicholson, A. M. (1980). Hypnotics: rebound insomnia and residual sequelae. Br. J. Clin. Pharmacol., 9, 223-225.
38. 3H flunitrazepam binding sites. J. Neurochem., 49, 890-898.
39. Oates, J., Wood, A., Gillin, C. and Byerley, W. (1990). The diagnosis and management of insomnia. N. Engl. J. Med., 332, 239-248.
40. Ongini, E. (1983). Behavioral and EEC effects of benzodiazepines and their antagonists in the cat. In Benzodiazepines Recognition Site Ligands: Biochemistry and Pharmacology, Bigio, G. and Costa, E. (Eds). Raven Press, New York, pp. 211-225.
41. Oswald, I. (1985). Withdrawal symptoms and rebound anxiety after six weeks course of diazepam. Br. Med. J., 290, 1827.
42. Perrault, G., Morel, E., Sanger, D. and Zorkovic, B. (1990). Differences in pharmacological profiles of a new generation of benzodiazepine and non-benzodiazepine hypnotics. Eur. J. Pharmacol., 187, 487-494.
43. Power, K. G., Jerrom, D. W. A., Simpson, R. J. and Mitchell, M. (1985). Controlled study of withdrawal symptoms and rebound anxiety after six week course of diazepam for generalized anxiety. Br. Med. J., 290, 1246-1248.
44. Rickels, K., George, C., Schweizer, E., Swenson, C. and Fridman, R. (1986). Low dose dependence in chronic benzodiazepine users. A preliminary report on 119 patients. Psychopharmacol. Bull., 2, 407-415.
45. Roehrs, T. A., Zorick, F. J., Wittig, R. M. and Roth, T. (1986). Dose determinants of rebound insomnia. Br. J. Clin. Psychopharmacol., 22, 143-147.
46. Silvestri, R., Ferrillo, F., Murri, L., Marretani, R., Di Perri, R., Rosadini, G., Montesano, A., Borghi, C. and de la Giclais, B. (1996). Rebound insomnia after abrupt discontinuation of hypnotic treatment: double-blind randomized comparison of Zolpidem versus Triazolam. Human Psychopharmacology, 11, 225-233.
47. Tyrer, P. and Owen, R. (1983). Gradual withdrawal of diazepam after long-term therapy. Lancet, 1, 1402-1406.
48. Tyrer, P., Rutherford, D. and Hugett, T. (1981). Benzodiazepine withdrawal symptoms and propranolol. Lancet, 1, 520-522.
49. Ueki, S. (1987). Behavioral pharmacology of zopiclone. Sleep, 10 (suppl. 1), 1-6.
50. Woods, J. H., Katz, J. L. and Winger, G. (1988). Use and abuse of benzodiazepines. JAMA, 260, 3476-3480.