Misfolding of chloramphenicol acetyltransferase due to carboxy-terminal truncation can be corrected by second-site mutations

Protein Engineering

Volumn 11, Issue 12, 1998, Pages 1211-1217

  Van Der Schueren, J ^a   Robben, J ^a   Volckaert, G ^a  

^a LABORATORY OF GENE TECHNOLOGY   (Belgium)

Author keywords

Enzyme evolution; Inclusion bodies; Protein folding; Protein stability; Random mutagenesis

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; ENZYME CONFORMATION; ESCHERICHIA COLI; MUTAGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY;

EID: 0032409047     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/11.12.1211     Document Type: Article

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