Blood-brain barrier damage in reperfusion following ischemia in the hippocampus of the Mongolian gerbil brain

Acta Neurologica Scandinavica

Volumn 98, Issue 6, 1998, Pages 406-411

  Shinnou, M ^a   Ueno, M ^a   Sakamoto, H ^b   Ide, M ^a  

^a KAGAWA UNIVERSITY   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

Blood brain barrier; Hippocampus; Horseradish peroxidase; Ischemia; Mongolian gerbil; Tetramethyl benzidine

Indexed keywords

DIAMINOBENZIDINE; HORSERADISH PEROXIDASE; TETRAMETHYLBENZIDINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN ISCHEMIA; CAROTID ARTERY OBSTRUCTION; CELL VACUOLE; COMMON CAROTID ARTERY; ELECTRON MICROSCOPY; FEMALE; GERBIL; HIPPOCAMPUS; MEMBRANE VESICLE; MICROSCOPY; NONHUMAN; REPERFUSION; ULTRASTRUCTURE;

EID: 0032408976     PISSN: 00016314     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0404.1998.tb07322.x     Document Type: Article

References (34)

1. ITO U, SPATZ M, WALKER JR JT, KLATZO I. Experimental cerebral ischemia in Mongolian gerbils. Light microscopic observations. Acta Neuropathol 1975;32:209-23.
2. KIRINO T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 1982;239:57-69.
3. PULSINELLI WA, BRIERLEY JB, PLUM F. Temporal profile of neuronal damage in a model of transient forebrain ischemia. Ann Neurol 1982;ll:491-8.
4. ROSEMBLUM WI. Histopathologic clues to the pathways of neuronal death following ischemia/hypoxia. J Neurotrauma 1997;14:313-26.
5. YAMAMOTO K, HAYAKAWA T, MOGAMI H, AKAI F, YANAGI-HARA T. Ultrastructural investigation of the CAl region of the hippocampus after transient cerebral ischemia in gerbils. Acta Neuropathol 1990;80:487-92.
6. YANAGIHARA T, YOSHIMIXE T, MORIMOTO K, YAMAMOTO K, HOMBURGER HA. Immunohistochemical investigation of cerebral ischemia in gerbils. J Neuropathol Exp Neurol 1985;44:204-15.
7. HOSSMANN K-A, OLSSON Y. The effect of transient cerebral ischemia on the vascular permeability to protein tracers. Acta Neuropathol 1971;18:103-12.
8. ITO U, Go KG, WALKER JR JT, SPATZ M, KLATZ I. Experimental cerebral ischemia in Mongolian gerbils. III. Behavior of the blood-brain barrier". Acta Neuropathol 1976;34:l-6.
9. IWASAKI Y, ITO S, SUZUKI M, NAGAHORI T, YAMAMOTO T, KONNO H. Forebrain ischemia induced by temporary bilateral common carotid occlusion in normotensive rats. J Neurol Sei 1989;90:155-65.
10. LOSSINSKY AL, GARCIA JH, IWANOWSKI L, LIGIIITOOTEJR WE. New ultrastructural evidence for a protein transport system in endothelial cells of gerbil brains. Acta Neuropathol 1979;47:105-10.
11. OLSSON Y, CROWELL RM, KLATZO I. The blood-brain barrier to protein tracers in focal cerebral ischemia and infarction caused by occlusion of the middle cerebral artery. Acta Neuropathol 1971;18:89-102.
12. PETITO CK. Early and late mechanisms of increased vascular permeability following experimental cerebral infarction. J Neuropathol Exp Neurol 1979;38:222-34.
13. WESTERGAARD E, Go KG, KLATZO I, SPATZ M. Increased permeability of cerebral vessels to horseradish peroxidase induced by ischemia in Mongolian gerbils. Acta Neuropathol 1976;35:307-25.
14. KITAGAWA K, MATSUMOTO M, TAGAYA M et al. Temporal profile of serum albumin extravasation following cerebral ischemia in a newly established reproducible gerbil model for vasogenic brain edema: a combined immunohistochemical and dye tracer analysis. Acta Neuropathol 1991;82:16471.
15. KITAGAWA K, MATSUMOTO M, OIITSUKI T et al. The characteristics of blood-brain barrier in three different conditions - infarction, selective neuronal death and selective loss of presynaptic terminals - following cerebral ischemia. Acta Neuropathol 1992;84:378-86.
16. MAEDA M, AKAI F, NISHIDA S, YANACIHARA T. Intracerebral distribution of albumin after transient cerebral ischemia: light and electron microscopic immunocytochemical investigation. Acta Neuropathol 1992;84:59-66.
17. SCHMIDT-KASTNER R, SZYMAS J, HOSSMANN K-A. Immunohistochemical study of glial reaction and serum-protein extravasation in relation to neuronal damage in rat hippocampus after ischemia. Neuroscience 1990;38:527-40.
18. REESE TS, KARNOVSKY MJ. Fine structural localization of a blood-brain barrier to exogenous peroxidase. J Cell Biol 1967;34:207-17.
19. VILLEGAS JC, BROADWELL RD. Transcytosis of protein through the mammalian cerebral epithelium and endothelium. II. Adsorptive transcytosis of WGA-HRP and the blood-brain and brain-blood barriers. J Neurocytol 1993;22:67-80.
20. VORBRODT AW, DOBROGOWSKA DH, LOSSINSKY AS. Ultracytochemical studies of the effects of aluminum on the blood-brain barrier of mice. J Histochem Cytochem 1994;42:203-12.
21. WESTERGAARD E, BRIGIITMAN MW. Transport of protein across normal cerebral arterioles. J Comp Neurol 1973;152:17-44.
22. SUZUKI M, IWASAKI Y, UMEZAWA K, MOTOIIASHI O, SUIDA N. Distribution of extravasated serum protein after cryoinjury in neonatal and adult rat brains. Acta Neuropathol 1995;89:532-6.
23. UENO M, DOBROGONVSKA DH, VORBRODT AW. Immunocytochemical evaluation of the blood-brain barrier to endogenous albumin in the olfactory bulb and pons of senescence-accelerated mice (SAM). Histochem Cell Biol 1996;105:203-12.
24. VORBRODT AW, DOBROGOWSKA DH, UENO M, LOSSINSKY AS. Immunocytochemical studies of protamine-induced bloodbrain barrier opening to endogenous albumin. Acta Neuropathol 1995;89:491-9.
25. DAVSOM H, WELCH K, SEGAL MB. Some special aspects of the blood-brain barrier. In: DAVSON H, WELCH K, SEGAL MB, eds. The physiology and pathophysiology of the cerebrospinal fluid. Edinburgh, London, Melbourne and New York: Churchill Livingstone, 1987:247-374.
26. MESULAM M-M. Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction-product with superior sensitivity for visualizing neural afférents and afférents. J Histochem Cytochem 1978;26:106-17.
27. BALIN BJ, BROADWELL RD, SALCMAN M, EL-KALLINY M. Avenues for entry of peripherally administered protein to the central nervous system in mouse, rat and squirrel monkey. J Comp Neurol 1986;251:260-80.
28. BANKS WA, BROADWELL RD. Blood to brain and brain to blood passage of native horseradish peroxidase, wheat germ agglutinin, and albumin: pharmacokinetic and morphological assessments. J Neurochem 1994;62:240419.
29. BROADWELL RD, SOFRONIEW MV. Serum proteins bypass the blood-brain fluid barriers for extracellular entry to the central nervous system. Exp Neurol 1993;120:245-63.
30. UENO M, AKIGUCIII I, HOSOKAWA M et al. Accumulation of blood-borne horseradish peroxidase in medial portions of the mouse hippocampus. Acta Neurol Scand 1994;90:4004.
31. UENO M, AKIOUCHI I, HOSOKAWA M et al. Age-related changes in the brain transfer of blood-borne peroxidase in the hippocampus of senescence-accelerated mouse. Acta Neuropathol 1997;93:233-40.
32. UENO M, AKIGUCHI I, HOSOKAWA M et al. Ultrastructural and permeability features of microvessels in the olfactory bulbs of SAM mice. Acta Neuropathol (In press.).
33. GRAIN BJ, BURGER PC. The laminar distribution of neuritic plaques in the fascia dentata of patients with Alzheimer's disease. Acta Neuropathol 1988;76:87-93.
34. PETITO CK, PULSINELLI W A, JACOBSON G, PLUM F. Edema and vascular permeability in cerebral ischemia: comparison between ischémie neuronal damage and infarction. J Neuropathol Exp Neurol 1982;41:423-36.