The large T antigen of simian virus 40 binds and inactivates p53 but not p73

Journal of General Virology

Volumn 79, Issue 12, 1998, Pages 3079-3083

  Dobbelstein, Matthias ^a   Roth, Judith ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; VIRUS LARGE T ANTIGEN;

ARTICLE; JC VIRUS; PRIORITY JOURNAL; SIMIAN VIRUS 40; VIRUS TRANSCRIPTION;

DNA VIRUSES; JC VIRUS; SIMIAE; SIMIAN VIRUS; SIMIAN VIRUS 40;

EID: 0032407889     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-79-12-3079     Document Type: Article

References (8)

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2. Bollag, B., Chuke, W. F. & Frisque, R. J. (1989). Hybrid genomes of the polyomaviruses JC virus, BK virus, and simian virus 40: identification of sequences important for efficient transformation. Journal of Virology 63, 863-872.
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6. Jiang, D., Srinivasan, A., Lozano, G. & Robbins, P. D. (1993). SV40 T antigen abrogates p53-mediated transcriptional activity. Oncogene 8, 2805-2812.
7. Jost, C. A., Marin, M. C. & Kaelin, W. G., Jr (1997). P73 is a human p53-related protein that can induce apoptosis. Nature 389, 191-194.
8. Kaelin, W. G., Jr (1998). Another p53 Doppelganger? Science 281, 57-58.