Hydrophilic Thr can replace the hydrophobic and absolutely conservative A3Val in insulin

Biochimica et Biophysica Acta - Protein Structure and Molecular Enzymology

Volumn 1429, Issue 1, 1998, Pages 69-73

  Chen, Hui ^a   Feng, You Min ^a  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

Hydrophobic surface; Mutant insulin; Receptor binding; Site directed mutagenesis

Indexed keywords

INSULIN; INSULIN DERIVATIVE; INSULIN[A3 THREONINE]; UNCLASSIFIED DRUG;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CRYSTALLIZATION; DNA SEQUENCE; DRUG ACTIVITY; ESCHERICHIA COLI; FEMALE; HUMAN; HUMAN TISSUE; MOLECULAR CLONING; MOUSE; MUTANT; NONHUMAN; NORMAL HUMAN; PLACENTA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; RECEPTOR BINDING; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

EID: 0032407582     PISSN: 01674838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-4838(98)00219-2     Document Type: Article

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