Lysophosphatidylcholine acyltransferase activity in Saccharomyces cerevisiae: Regulation by a high-affinity Zn2+ binding site

Lipids

Volumn 33, Issue 12, 1998, Pages 1229-1234

  Richard, Martin G ^a   McMaster, Christopher R ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1 ACYLGLYCEROPHOSPHOCHOLINE ACYLTRANSFERASE; ZINC ION;

ARTICLE; BINDING SITE; ENZYME ACTIVITY; ENZYME REGULATION; METAL BINDING; NONHUMAN; PHOSPHOLIPID METABOLISM; SACCHAROMYCES CEREVISIAE;

1-ACYLGLYCEROPHOSPHOCHOLINE O-ACYLTRANSFERASE; BINDING SITES; SACCHAROMYCES CEREVISIAE; SUBSTRATE SPECIFICITY; ZINC;

SACCHAROMYCES CEREVISIAE;

EID: 0032405733     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-998-0328-1     Document Type: Article

References (35)

1. Zinser, E., Sperka-Gottlieb, S., Fasch, E.-V., Kohlwein, S.D., Paltauf, F., and Daum, G. (1991) Phospholipid Synthesis and Lipid Composition of Subcellular Membranes in the Unicellular Eukaryote Saccharomyces cerevisiae, J. Bacteriol. 173, 2026-2034.
2. Kent, C. (1995) Eukaryotic Phospholipid Biosynthesis, Annu. Rev. Biochem. 64, 315-343.
3. Vance, D.E. (1996) Glycerolipid Biosynthesis in Eukaryotes, in Biochemistry of Lipids, Lipoproteins and Membranes (Vance, D.E., and Vance, J.E., eds.), Vol. 31, pp. 153-181, Elsevier Science B.V., Amsterdam.
4. McMaster, C.R., and Bell, R.M. (1997) CDP-Choline:1,2-Diacylglycerol Cholinephosphotransferase, Biochim. Biophys. Acta 1348, 100-110.
5. Lands, W.E.M. (1960) Metabolism of Glycerolipids, J. Biol. Chem. 235, 2233-2237.
6. 14C]Linoleic Acid in Rat Liver, Biochim. Biophys. Acta 218, 57-70.
7. Schmid, P.C., Johnson, S.B., and Schmid, H.O. (1991) Remodeling of Rat Hepatocyte Phospholipids by Selective Acyl Turnover, J. Biol. Chem. 266, 13690-13697.
8. Bakken, A.M., and Farstad, M. (1992) The Activities of Acyl-CoA:1-Acyl-Lysophospholipid Acyltransferase(s) in Human Platelets, Biochem. J. 288, 763-770.
9. DeWitt, D., and Smith, W.L. (1995) Yes, but Do They Still Get Headaches? Cell 83, 345-348.
10. Choy, P.C., Skrzypczak, M., Lee, D., and Jay, F.T. (1997) Acyl-GPC and Alkenyl/Alkyl-GPC:acyl-CoA Acyltransferases, Biochim. Biophys. Acta 1348, 124-133.
11. Williams, J.G., and McMaster, C.R. (1998) Scanning Alanine Mutagenesis of the CDP-alcohol Phosphotransferase Motif of Saccharomyces cerevisiae Cholinephosphotransferase, J. Biol. Chem. 273, 13482-13487.
12. Choy, P.C., Tardi, P.G., and Mukherjee, J.J. (1992) Lysophosphatidylcholine Acyltransferase, Methods Enzymol. 209, 80-86.
13. Choy, P.C., and McMaster, C.R. (1992) 1-Alkyl-and 1-Alkenylglycerophosphocholine Acyltransferases, Methods Enzymol. 209, 86-92.
14. Folch, J., Lees, M, and Sloane-Stanley, G.H. (1957) A Simple Method for the Isolation and Purification of Total Lipides from Animal Tissues, J. Biol. Chem. 226, 497-506.
15. Ames, B.N., and Dubin, D.R. (1960) The Role of Polyamines in the Neutralization of Bacteriophage Deoxyribonucleic Acid, J. Biol. Chem. 235, 769-775.
16. Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J. (1951) Protein Measurement with the Polin Phenol Reagent, J. Biol. Chem. 193, 265-275.
17. Lineweaver, H., and Burk, D. (1934) The Determination of Enzyme Dissociation Constants, J. Am. Chem. Soc. 56, 658-666.
18. Paltauf, F., Kohlwein, S.D., and Henry, S.A. (1992) Regulation and Compartmentalization of Lipid Synthesis in Yeast, in The Molecular Biology of the Yeast Saccharomyces: Gene Expression (Pringle, J.R., Broach, J.R., and Jones, E.W., eds.), Vol. 2, pp. 415-500, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York.
19. McMaster, C.R., Morash, S.C., and Bell, R.M. (1996) Phospholipid and Cation Activation of Chimaeric Choline/Ethanolamine Phosphotransferases, Biochem. J. 313, 729-735.
20. Mosior, M., Golini, E.-S., and Epand, R.M. (1996) Chemical Specificity and Physical Properties of the Lipid Bilayer in the Regulation of Protein Kinase C by Anionic Phospholipids: Evidence for the Lack of a Specific Binding Site for Phosphatidylserine, Proc. Natl. Acad. Sci. USA 93, 1907-1912.
21. Weinhold, P.A., and Barrett, D. (1998) Studies on the Regulation of CTP:Phosphocholine Cytidylyltransferase Using Permeabilized HEP G2 Cells: Evidence That Both Active and Inactive Enzymes Are Membrane-Bound, Biochim. Biophys. Acta 1391, 307-319.
22. Kessler, E., Safrin, M., Abrams, W.R., Rosenbloom, J., and Ohman, D.E. (1997) Inhibitors and Specificity of Pseudomonas aeruginosa LasA, J. Biol. Chem. 272, 9884-9889.
23. Kim, K.I., Baek, S.H., Hong, Y.-M., Kang, M.-S., Ha, D.B., Goldberg, A.L., and Chung, C.H. (1995) Purification and Characterization of Protease Ci, a Cytoplasmic Metalloendoprotease in Escherichia coli, J. Biol. Chem. 270, 29799-29805.
24. Mallya, S.K., and Van Wart, H.E. (1989) Mechanism of Inhibition of Human Neutrophil Collagenase by Gold(I) Chrysotherapeutic Compounds. Interaction at a Heavy Metal Binding Site J. Biol. Chem. 264, 1594-1601.
25. Snyder, F. (1996) Ether-Linked Lipids and Their Bioactive Species: Occurrence, Chemistry, Metabolism, Regulation, and Function, in Biochemistry of Lipids, Lipoproteins and Membranes (Vance, D.E., and Vance, J.E., eds.), Vol. 31, pp. 183-210, Elsevier Science B.V., Amsterdam.
26. Lee, K.S., Patton, J.L., Fido, M., Hines, L.K., Kohlwin, S.D., Paltauf, F., Henry, S.A., and Levin, D.E. (1994) The Saccharomyces cerevisiae PLB1 Gene Encodes a Protein Required for Lysophospholipase and Phospholipase B Activity, J. Biol. Chem. 269, 19725-19730.
27. Rooney, S.A., Young, S.L., and Mendelson, C.R. (1994) Molecular and Cellular Processing of Lung Surfactant, FASEB J. 8, 957-967.
28. Gassic, A.C., McGuire, G., Krater, S., Farhood, A.I., Goldstein, M.A., Smith, C.W., Entman, M.L., and Taylor, A.A. (1991) Hydrogen Peroxide Pretreatment of Perfused Canine Vessels Induces ICAM-1 and CD18-Dependent Neutrophil Adherence, Circulation 84, 2154-2166.
29. Suzuki, M., Asako, H., Kubes, P., Jennings, S., Grisham, M.B., and Granger, D.N. (1991) Neutrophil-Derived Oxidants Promote Leukocyte Adherence in Postcapillary Venules, Microvas. Res. 42, 125-138.
30. Yamada, K., Okuyama, H., Endo, Y., and Ikezawa, H. (1977) Acyltransferase Systems Involved in Phospholipid Metabolism in Saccharomyces cerevisiae, Arch. Biochem. Biophys. 183, 281-289.
31. Wagner, S., and Paltauf, F. (1994) Generation of Glycerophospholipid Molecular Species in the Yeast Saccharomyces cerevisiae. Fatty Acid Pattern of Phospholipid Classes, Yeast 10, 1429-1437.
32. Arthur, G.A., and Choy, P.C. (1986) Acylation of 1-Alkenylglycerophosphocholine and 1-Acyl-glycerophosphocholine in Guinea Pig Heart, Biochem. J. 236, 481-487.
33. Hansen, H.P., Kisseleva, T., Kobarg, J., Horn-Lohrens, O., Havsteen, B., and Lemke, H. (1995) A Zinc Metalloproteinase Is Responsible for the Release of CD30 on Human Tumor Cell Lines, Int. J. Cancer 63, 750-756.
34. Leidich, S.D., Drapp, D.A., and Orlean, P. (1995) Isolation and Characterization of Yeast Glycosylphosphatidylinositol Anchoring Mutants, Methods Enzymol. 250, 560-571.
35. Swede, M.J., Hudak, K.A., Lopes, J.M., and Henry, S.A. (1992) Strategies for Generating Phospholipid Synthesis Mutants in Yeast, Methods Enzymol. 209, 21-43.