Convenient solid-phase synthesis of Tyr3-octreotide

Applied Radiation and Isotopes

Volumn 49, Issue 12, 1998, Pages 1581-1586

  Lee, T E Wei ^a   Chang, Shiang Rong ^a   Chen, Shui Tein ^b   Tsai, Zei Tsan ^a  

^a INSTITUTE OF NUCLEAR ENERGY RESEARCH   (Taiwan)

^b INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IODINE; MASS SPECTROMETERS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OXIDATION; SYNTHESIS (CHEMICAL);

CYCLIZATION; DIMETHYLFORMAMIDE; ELECTROSPRAY MASS SPECTROMETRY; SOLID PHASE SYNTHESIS;

AMINO ACIDS;

IODINE; IODINE 123; N,N DIMETHYLFORMAMIDE; OCTREOTIDE[3 TYROSINE]; RESIN; SOMATOSTATIN RECEPTOR; TRIFLUOROACETIC ACID;

ARTICLE; CYCLIZATION; DISULFIDE BOND; DRUG PURIFICATION; MASS SPECTROMETRY; OXIDATION; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RADIOIODINATION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 0032404487     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8043(98)00003-7     Document Type: Article

References (5)

1. Albericio, F., Hammer, R. P., Garcia-Echeverria, C., Molins, M. A., Chang, J. L., Munson, M. C., Pons, M., Giralt, E. and Barany, G. (1991) Cyclization of disulfide-containing peptide in solid-phase synthesis. Int. J. Peptide Protein Res. 37, 402-413.
2. Bakker, W. H., Krenning, E. P., Breeman, W. A., Koper, J. W., Kooij, P. P., Reubi, J.-C., Klijn, J. G., Visser, T. J., Doctor, R. and Lamberts, S. W. (1990) Receptor scintigraphy with a radioiodinated somatostatin analogue: radiolabeling, purification, biologic activity, and in vivo application in animals. J. Nucl. Med. 31, 1501-1509.
3. Bauer, W. and Pless, J. (1983) Novel polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use. U.S. Pat. 4395403.
4. Kwekkeboom, D. J., Krenning, E. P. and Bakker, W. H. (1991) Radioiodinated somatostatin analog scintigraphy in small-cell lung cancer. J. Nucl. Med. 32, 1845-1848.
5. Neugebauer, W. and Escher, E. (1989) Solid-phase synthesis of C-terminal peptide amino alcohols. Helv. Chim. Acta 72, 1319-1323.