Synthesis of aryl semicarbazone of 4-aminoacetophenone and their anti- HIV activity

Pharmaceutica Acta Helvetiae

Volumn 73, Issue 4, 1998, Pages 215-218

  Mishra, Vibha ^a   Pandeya, S N ^a   DeClercq, E ^b   Pannecouque, Christophe ^b   Witvrouw, Myriam ^b  

^a BANARAS HINDU UNIVERSITY   (India)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Anti HIV; Semicarbazone; Thioureido

Indexed keywords

ACETOPHENONE DERIVATIVE; SEMICARBAZONE DERIVATIVE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; STRUCTURE ANALYSIS;

ACETOPHENONES; ANTI-HIV AGENTS; CELL LINE, TRANSFORMED; HIV-1; HIV-2; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; SEMICARBAZONES;

EID: 0032402543     PISSN: 00316865     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-6865(98)00028-4     Document Type: Article

References (8)

1. Clavel et al., 1986.
2. DeClercq E. J. Med. Chem. 38:1995;2491.
3. Merluzzi V.J., Hargrave K.D., Labadia M., Grozinger K., Skoog M., Wu J.C., Shin C.K., Eckner K., Hattox S., Adams J., Rosenthal A.S., Faanes R., Eckner R.J., Koup R.A., Sullivan J.L. Science. 250:1990;1411.
4. Pauwels R., DeClercq E., Desmyter J., Balzarini J., Goubau P., Herdewijn P., Vandeputte M. J. Virol. Methods. 16:1987;171.
5. Pauwels R., Andries K., Desmeyter J., Schols D., Kukla M.J., Breslin H.J., Raeymaeckers A., Van Gelder J., Woestenborghs R., Heykants J., Schellekens K., Janssen M.A.C., DeClercq E., Janssen P.A. Nature. 343:1990;470.
6. Popovic et al., 1984.
7. Sah Ma. J. Chinese Chem. Soc. 2:1934;32.
8. Wilkerson W.W., Dax S., Cheathem W.W. J. Med. Chem. 40:1997;4079.