The performance of CA-125 measurement in the detection of endometriosis: A meta-analysis

Fertility and Sterility

Volumn 70, Issue 6, 1998, Pages 1101-1108

  Mol, Ben W J ^a,b   Bayram, Neriman ^b   Lijmer, Jeroen G ^b   Wiegerinck, Maarten A H M ^a   Bongers, Marlies Y ^a   Van Der Veen, Fulco ^b   Bossuyt, Patrick M M ^b  

^a ST JOSEPH HOSPITAL   (Netherlands)

^b UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

CA 125; Diagnosis; Endometriosis; Meta analysis; Subfertility

Indexed keywords

CA 125 ANTIGEN;

ANAMNESIS; ANTIGEN EXPRESSION; ARTICLE; BLOOD LEVEL; CLINICAL TRIAL; DIAGNOSTIC VALUE; ENDOMETRIOSIS; FEMALE; FEMALE INFERTILITY; HUMAN; LABORATORY DIAGNOSIS; LAPAROSCOPY; META ANALYSIS; PHYSICAL EXAMINATION; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC;

CA-125 ANTIGEN; ENDOMETRIOSIS; FEMALE; HUMANS; LAPAROSCOPY; PREDICTIVE VALUE OF TESTS; REFERENCE STANDARDS; ROC CURVE; SENSITIVITY AND SPECIFICITY;

EID: 0032402314     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(98)00355-0     Document Type: Article

References (44)

1. Olive D.L., Schwartz L.B. Endometriosis. N Engl J Med. 328:1993;1759-1769.
2. Collins J.A., Burrows E.A., Willan A.R. The prognosis for live birth among untreated infertile couples. Fertil Steril. 64:1995;22-28.
3. Marcoux S., Maheux R., Bérubé S. Laparoscopic surgery in infertile women with minimal or mild endometriosis. N Engl J Med. 337:1997;217-222.
4. Koninckx P.R., Meuleman C., Demeyere S., Cornillie F.J. Suggestive evidence that pelvic endometriosis is a progressive disease, whereas deeply infiltrating endometriosis is associated with pelvic pain. Fertil Steril. 55:1991;759-765.
5. Koninckx P.R., Martin D.C. Deep endometriosis a consequence of infiltration or retraction or possibly adenomyosis externa? Fertil Steril. 58:1992;924-928.
6. Koninckx P.R., Oosterlynck D., D'Hooghe T.M., Meuleman C. Deeply infiltrating endometriosis is a disease whereas mild endometriosis could be considered as non-disease. Ann NY Acad Sci. 734:1994;333-341.
7. Barbieri R.L., Niloff J.M., Bast R.C. Jr, Scaetzl E., Kistner R.W., Knapp R.C. Elevated serum concentrations of CA-125 in patients with advanced endometriosis. Fertil Steril. 45:1986;630-634.
8. Pittaway D.E., Fayez J.A. The use of CA-125 in the diagnosis and management of endometriosis. Fertil Steril. 46:1986;790-795.
9. Moretuzzo R.W., DiLauro S., Jenison E., Chen S.L., Reindollar R.H., McDonough P.G. Serum and peritoneal lavage fluid CA-125 levels in endometriosis. Fertil Steril. 50:1988;430-433.
10. Franchi M., Beretta P., Zanaboni F., Donadello N., Ghezzi F. Use of serum CA-125 measurement in patients with endometriosis. Br J Obstet Gynaecol. 4:1993;149-152.
11. Barbati A., Cosmi E.V., Spaziani R., Ventura R., Montanino G. Serum and peritoneal fluid CA-125 levels in patients with endometriosis. Fertil Steril. 61:1994;438-442.
12. Irwig L., Tosteton A., Gatsonis C., Lau J., Colditz G., Chalmers T.C., et al. Guidelines for meta-analyses evaluating diagnostic tests. Ann Intern Med. 120:1994;667-676.
13. Mol B.W.J., Dijkman A.B., Wertheim P., Lijmer J., Van der Veen F., Bossuyt P.M.M. The accuracy of chlamydia antibodies in the diagnosis of tubal pathology a meta-analysis . Fertil Steril. 67:1997;1031-1037.
14. Centor R.M., Schwartz S.J. An evaluation of methods for estimating the area under the receiver operating characteristic (ROC) curve. Med Decis Making. 5:1985;149-156.
15. SAS technical report P-242, SAS changes and enhancements, release 6. 08. 1993;13-16 SAS Institute Inc, Cary (NC).
16. Patton P.E., Field C.S., Harms R.W., Coulam C.B. CA-125 levels in endometriosis. Fertil Steril. 45:1986;770-773.
17. Lanzone A., Marana R., Muscatello R., Fulghesu A.M., Dell'Acqua S., Caruso A., et al. Serum CA-125 levels in the diagnosis and management of endometriosis. J Reprod Med. 36:1991;603-607.
18. Molo M.W., Kelly M., Radwanska E., Binor Z. Preoperative serum CA-125 and CA-72 in predicting endometriosis in infertility patients. J Reprod Med. 39:1994;964-966.
19. Hornstein M.D., Harlow B.L., Thomas P.P., Check J.H. Use of a new CA-125 assay in the diagnosis of endometriosis. Hum Reprod. 10:1995;932-934.
20. Moloney M.D., Thornton J.G., Cooper E.H. Serum CA-125 antigen levels and disease severity in patients with endometriosis. Obstet Gynecol. 73:1989;767-769.
21. O'Shaughnessy A., Check J.H., Nowroozi K., Lurie D. CA-125 levels measured in different phases of the menstrual cycle in screening for endometriosis. Obstet Gynecol. 81:1993;99-103.
22. Ozaksit G., Caglar T., Cicek N., Kuscu E., Batioglu S., Gokmen O. Serum CA-125 levels before, during and after treatment for endometriosis. Int J Gynaecol Obstet. 50:1995;269-273.
23. Koninckx P.R., Meuleman C., Oosterlynck D., Cornillie F.J. Diagnosis of deep endometriosis by clinical examination during menstruation and plasma CA-125 concentration. Fertil Steril. 65:1996;280-287.
24. Colacurci N., Fortunato N., De Franciscis P., Cardone A. Relevance of CA-125 in the evaluation of endometriosis. Clin Exp Obstet Gynecol. 23:1996;150-154.
25. Fedele L., Vercellini P., Arcaini L., Grazia de Dalt M., Candianni B.C. CA-125 in serum, peritoneal fluid, active lesions, and endometrium of patients with endometriosis. Am J Obstet Gynecol. 158:1988;166-170.
26. Fedele L., Arcaini L., Vercellini P., Marchini M., Baglioni A., Bianchi S. Serum CA-125 concentrations in endometriosis. Acta Eur Fertil. 20:1989;137-139.
27. Muscatello R., Cucinelli F., Fulghesu A., Lanzone A., Caruso A., Mancuso S. Multiple serum marker assay in the diagnosis of endometriosis. Gynecol Endocrinol. 6:1992;265-269.
28. Gurgan T., Kisnisci H., Yarali H., Aksu T., Zeyneloglu H., Develioglu O. Serum and peritoneal fluid CA-125 levels in early stage endometriosis. Gynecol Obstet Invest. 30:1990;105-108.
29. Fisk N.M., Tan C.E. CA-125 in peritoneal fluid and serum of patients with endometriosis. Eur J Obstet Gynecol Reprod Biol. 29:1988;153-158.
30. Medl M., Ogris E., Peters-Engl C., Mierau M., Buxbaum P., Leodolter S. Serum levels of the tumour-associated trypsin inhibitor in patients with endometriosis. Br J Obstet Gynaecol. 104:1997;78-81.
31. Kruitwagen R.F.P.M., Thomas C., Poels L.G., Koster A.M., Willemsen W.N.P., Rolland R. High CA-125 concentrations in peritoneal fluid of normal cyclic women with various infertility-related factors as demonstrated with two-step immunoradiometric assay. Fertil Steril. 56:1991;863-869.
32. Berral J.E., Puertas P.I.C., Avisbal M.T., Capote C.P., Casas J.A.V., Velsaco A.B., et al. Niveles sericos de CA-125 y CA 19.9 en el diagnostico de pacientes con sospecha clinica de endometriosis. Rev Esp Med Nuclear. 15:1996;71-76.
33. Takahashi K., Nagata H., Abu Musa A., Shibukawa T., Yamasali H., Kitao M. Clinical usefulness of CA-125 levels in the menstrual discharge in patients with endometriosis. Fertil Steril. 54:1990;360-362.
34. Masahashi T., Matsuzawa M., Narita O., Asai T., Ishihara M. Serum CA-125 levels in patients with endometriosis changes in CA-125 levels during menstruation . Obstet Gynecol. 72:1989;328-331.
35. Malkasian G.D., Podratz K.C., Stanhope R., Ritts R.E., Zurawski V.R. Jr. CA-125 in gynecologic practice. Am J Obstet Gynecol. 155:1986;515-518.
36. Giudice L.C., Jacobs A., Pineda J., Bell C.E., Lippmann L. Serum levels of CA-125 in patients with endometriosis a preliminary report . Fertil Steril. 45:1986;876-878.
37. Pittaway D.E., Douglas J.W. Serum CA-125 in women with endometriosis and chronic pelvic pain. Fertil Steril. 51:1989;68-70.
38. Hornstein M.D., Thomas P.P., Gleason R.E., Barbieri R.L. Menstrual cyclicity of CA-125 in patients with endometriosis. Fertil Steril. 58:1992;279-283.
39. Koninckx P.R., Riittinen L., Seppala M., Cornillie F.J. CA-125 and placental protein 14 concentrations and peritoneal fluid of women with deeply infiltrating pelvic endometriosis. Fertil Steril. 57:1992;523-530.
40. Ismail J., Rotmensch J., Mercer L.J., Block B.S., Salti G.I., Holt J.A. CA-125 in peritoneal fluid from patients with nonmalignant gynecologic disorders. J Reprod Med. 39:1994;510-512.
41. Muzii L., Marana R., Pedulla S., Catalano G.F., Mancuso S. Correlation between endometriosis-associated dysmenorrhea and the presence of atypical lesions. Fertil Steril. 68:1997;19-22.
42. Vercellini P., De Giorgi O., Aimi G., Panazza S., Uglietta A., Crosignani P.G. Menstrual characteristics in women with and without endometriosis. Obstet Gynecol. 90:1997;264-268.
43. Fedele L., Bianchi S., Marchini M., Villa L., Brioschi D., Parazzini F. Superovulation with human menopausal gonadotropins in the treatment of infertility associated with minimal or mild endometriosis a controlled randomized study . Fertil Steril. 58:1992;28-31.
44. Tummon I.S., Asher L.J., Martin J.S.B., Tulandi T.T. Randomized controlled trial of superovulation and insemination for infertility associated with minimal or mild endometriosis. Fertil Steril. 68:1997;8-12.