Protein LA, a novel hybrid protein with unique single-chain Fv antibody- and Fab-binding properties

European Journal of Biochemistry

Volumn 258, Issue 2, 1998, Pages 890-896

  Svensson, Henrik G ^a   Hoogenboom, Hennie R ^b   Sjöbring, Ulf ^a  

^a LUND UNIVERSITY   (Sweden)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Hybrid protein; Ig binding protein; Protein A; Protein L

Indexed keywords

BINDING PROTEIN; FC RECEPTOR; HYBRID PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN LIGHT CHAIN;

AFFINITY CHROMATOGRAPHY; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; HUMAN; IMMUNOBLOTTING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; SURFACE PLASMON RESONANCE;

ANTIBODIES; BACTERIAL PROTEINS; BIOSENSING TECHNIQUES; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN KAPPA-CHAINS; PROTEIN BINDING; RECOMBINANT FUSION PROTEINS; STAPHYLOCOCCAL PROTEIN A; SURFACE PLASMON RESONANCE;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 0032401602     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1998.2580890.x     Document Type: Article

References (44)

1. Forsgren, A. & Sjöquist, J. (1966) 'Protein A' from S. aureus. I. Pseudo-immune reaction with human gamma-globulin. J. Immunol. 97, 822-827.
2. Björck, L. & Kronvall, G. (1984) Purification and some properties of streptococcal protein G, a novel IgG-binding reagent, J. Immunol. 133, 969-974.
3. Reis, K., Ayoub, E. & Boyle, M. (1984) Streptococcal Fc receptors, I. Isolation and partial characterization of the receptor from a group C stretococcus, J. Immunol. 132, 3091-3097.
4. Björck, L. (1988) Protein L. A novel bacterial cell wall protein with affinity for Ig L chains, J. Immunol. 140, 1194-1197.
5. Sjödahl, J. (1977) Repetitive sequences in protein A from Staphylococcus aureus. Arrangement of five regions within the protein, four being highly homologous and Fc-binding, Eur. J. Biochem. 73, 343-351.
6. Kastern, W., Sjöbring, U. & Björck, L. (1992) Structure of peptostreptococcal protein L and identification of a repeated immunoglobulin light chain-binding domain, J. Biol. Chem. 267, 12820-12825.
7. Guss, B., Eliasson, M., Olsson, A., Uhlén, M., Frej, A. K., Jörnvall, H., Flock, J. I. & Lindberg, M. (1986) Structure of the IgG-binding regions of streptococcal protein G. EMBO J. 5, 1567-1575.
8. Deisenhofer, J., Jones, T. A., Huber, R., Sjödahl, J. & Sjöquist, J. (1978) Crystallization, crystal analysis and atomic model of the complex formed by a human Fc fragment and fragment B of protein A from Staphylococcus aureus, Hoppe-Seyler Z. Physiol. Chem. 359, 975-985.
9. Deisenhofer, J. (1981) Crystallographic refinement and atomic models of a human Fc fragment and its complex with fragment B of protein A from Staphylococcus aureus at 2.9- and 2.8-A resolution. Biochemistry 20, 2361-2370.
10. Derrick, J. P. & Wigley, D. B. (1992) Crystal structure of a streptococcal protein G domain bound to an Fab fragment, Nature 359, 752-754.
11. Sauer-Eriksson, A. E., Kleywegt, G. J., Uhlén, M. & Jones, T. A. (1995) Crystal structure of the C2 fragment of streptococcal protein G in complex with the Fc domain of human IgG, Structure 3, 265-278.
12. Wikström, M., Sjöbring, U., Drakenberg, T., Forsen, S. & Björck, L. (1995) Mapping of the immunoglobulin light chain-binding site of protein L. J. Mol. Biol. 250, 128-133.
13. Minor, D. L. Jr & Kim, P. S. (1994) Context is a major determinant of beta-sheet propensity, Nature 371, 264-267.
14. Minor, D. L. Jr & Kim, P. S. (1994) Measurement of the beta-sheet-forming propensities of amino acids. Nature 367, 660-663.
15. Scalley, M. L. & Baker, D. (1997) Protein folding kinetics exhibit an Arrhenius temperature dependence when corrected for the temperature dependence of protein stability, Proc. Natl Acad. Sci. USA 94, 10636-10640.
16. Yi, Q. & Baker, D. (1996) Direct evidence for a two-state protein unfolding transition rom hydrogen-deuterium exchange, mass spectrometry, and NMR, Protein Sci. 5, 1060-1066.
17. Inganäs, M., Johansson, S. G. & Sjöquist, J. (1981) Further characterization of the alternative protein-A interaction of immunoglobulins: demonstration of an Fc-binding fragment of protein A expressing the alternative reactivity, Scand. J. Immunol. 14, 379-388.
18. Langone, J. J. (1982) Protein A of Staphylococcus aureus and related immunoglobulin receptors produced by streptococci and pneumonococci, Adv. Immunol. 32, 157-252.
19. II-associated reactivity of monoclonal human IgM. J. Immunol. 145, 1232-1238.
20. Sasso, E. H., Silverman, G. J. & Mannik, M. (1989) Human IgM molecules that hind staphylococcal protein A contain VHIII H chains, J. Immunol. 142, 2778-2783.
21. 2 that bind to staphylococcal protein A belong to the VHIII subgroup, J. Immunol. 147, 1877-1883.
22. Nilson, B. H. K., Solomon, A., Bjöick, L. & Akerström. B. (1992) Protein L from Peptostreptococcus magnus binds the κ light chain variable domain, J. Biol. Chem. 267, 2234-2239.
23. Akerström, B., Nilson, B. H. K., Hoogenboom, H. R. & Björck, L. (1994) On the interaction between single chain Fv antibodies and bacterial immunoglobulin-binding proteins. J. Immunol. Methods 177, 151-163.
24. Enokizono, J., Wikström, M., Sjöbring, U., Björck, L., Forsén, S., Arata, Y., Kato, K. & Shimada, I. (1997) NMR analysis of the interaction between protein L and Ig light chains, J. Mol. Biol. 270, 8-13.
25. Kronvall, G. & Williams, R. C. (1969) Differences in anti-protein A activity among IgG subgroups, J. Immunol. 103, 828-833.
26. Field, P. R., Shanker, S. & Murphy, A. M. (1980) The use of protein A-sepharose affinity chromatography for separation and detection of specific IgM antibody in acquired rubella infection: a comparison with absorption by staphylococci containing protein A and density gradient ultracentrifugation, J. Immunol. Methods 32, 59-70.
27. Solomon, A. (1976) Bence-Jones proteins and light chains of immunoglobulins, N. Engl. J. Med. 294, 17-22.
28. De Chateau, M., Nilson, B. H. K., Erntell, M., Myhre, E., Magnusson, C. G. M., Akerström, B. & Bjorck, L. (1993) On the interaction between protein L and immunoglobulins of various mammalian species, Scand. J. Immunol. 37, 399-405.
29. Nilson, B. H. K., Lögdberg, L., Kastern, W., Björck, L. & Akerström. B. (1993) Purification of antibodies using protein L-binding framework structures in the light chain variable domain, J. Immunol. Methods 164, 33-40.
30. Winter, G. & Milstein, C. (1991) Man-made anybodies, Nature 349, 293-299.
31. Hoogenboom, H. R. (1997) Designing and optimizing library selection strategies for generating high-affinity antibodies, Trends Biotechnol. 15, 62-70.
32. Dalböge, H., Jensen, E. B., Tottrup, H., Grubb, A., Abrabamson, M., Olafsson, I. & Carlsen, S. (1989) High-level expression of active human cystatin C in Escherichia coli. Gene (Amst.) 79, 325-332.
33. Sambrook, J., Fritsch, E. F. & Maniatis, T. (1989) Molecular cloning. A laboratory manual. 2nd edn., Cold Spring Harbor Laboratory Press, Cold Spring Harbor NY.
34. Neville, D. M. Jr (1971) Molecular weight determination of protein-dodecyl sulfate complexes by gel electrophoresis in a discontinuous buffer system, J. Biol. Chem. 246, 6328-6334.
35. 128I-labelled human growth hormone of high specific activity. Biochem. J. 89, 114-123.
36. Mäkelä, O., Kaartinen, M., Pdlkonen, J. L. & Karjalanen, K. (1978) Inheritance of antibody specificity V. Anti-2-phenyloxazolone in the mouse, J. Exp. Med. 148, 1644-1660.
37. Akerström, B. & Björck, L. (1986) A physicochemical study of protein G, a molecule with unique immunoglobulin G-binding properties, J. Biol. Chem. 261, 10240-10247.
38. Roben, P. W., Salem, A. N. & Silverman, G. J. (1995) VH3 family antibodies bind domain D of staphylococcal protein A. J. Immunol. 154, 6437-6445.
39. Akerström, B. & Björck, L. (1989) Protein L: an immunoglobulin light chain-binding bacterial protein. Characterization of binding and physicochemical properties, J. Biol. Chem. 264, 19740-19746.
40. Young, W. W. Jr. Tamura, Y., Wolock, D. M. & Fox, J. W. (1984) Staphylococcal protein A binding to the Fab fragments of mouse monoclonal antibodies, J. Immunol. 133, 3163-3166.
41. Hillson, J. L., Karr, N. S., Oppliger, I. R., Mannik, M. & Sasso, E. H. (1993) The structural basis of germline-encoded VH3 immunoglobulin binding to slaphyloeoccal protein A. J. Exp. Med. 178, 331-336.
42. Potter, K. N., Li, Y. & Capra, J. D. (1996) Staphylococcal protein A simultaneously interacts with framework region I. complementarity-determining region 2, and framework region 3 on human VH3-encoded Igs, J. Immunol. 157, 2982-2988.
43. Eliasson, M., Olsson, A., Palmcrantz, E., Wiberg, K., Inganäs, M., Guss, B., Lindberg, M. & Uhlén, M. (1988) Chimeric IgG-binding receptors engineered from Staphylococcal protein A and streptococcal protein G. J. Biol. Chem. 263, 4323-4327.
44. Kihlberg, B. M., Sjöbring, U., Kastern, W. & Björck, I., (1992) Protein LG: a hybrid molecule with unique immunoglobulin binding properties, J. Biol. Chem. 267, 25583-25588.