Development of an abdominal magnetic resonance (MR) contrast agent formulation with Oral Magnetic Particles (OMP, Ferristene)

Pharmaceutica Acta Helvetiae

Volumn 73, Issue 4, 1998, Pages 205-213

  Matsumura, Manabu ^a   Nakagami, Hiroaki ^a   Chen, Chu Jun ^a   Ito, Shigekazu ^a   Konno, Tsutomu ^a  

^a Tokyo R and D Center   (Japan)

Author keywords

Contrast agent; Fluidized bed granulation; Magnetic resonance imaging; Oral Magnetic Particles; Oral suspension; Xanthan gum

Indexed keywords

NUCLEAR MAGNETIC RESONANCE IMAGING AGENT; ORAL MAGNETIC PARTICLE; UNCLASSIFIED DRUG;

ARTICLE; DRUG DESIGN; DRUG DOSAGE FORM; DRUG FORMULATION; DRUG MANUFACTURE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE IMAGING;

ABDOMEN; ANIMALS; CHEMISTRY, PHARMACEUTICAL; CHEMISTRY, PHYSICAL; CONTRAST MEDIA; FERRIC COMPOUNDS; MAGNETIC RESONANCE IMAGING; MALE; PARTICLE SIZE; RATS; RATS, SPRAGUE-DAWLEY; SUSPENSIONS; VISCOSITY;

EID: 0032401271     PISSN: 00316865     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-6865(98)00024-7     Document Type: Article

References (12)

1. Asahi Chemical Industry, 1990. Technical bulletin of Avicel RC-591, Japan.
2. Bach-Gansmo T., Dupas B., Gayet-Delacroix M., Lambrechts M. Abdomonal MRI using a negative contrast agent. Br. J. Radiol. 66:1993;420-425.
3. Boudghene F.P., Bach-Gansmo T., Grange J.D., Lame S., Nantoris C., Wallays C., Bigot J.M. Contribution of Oral Magnetic Particles in MR imaging of the abdomen with spin-echo and gradient-echo sequences. J. Magn. Reson. Imaging. 3:1993;107-112.
4. Davison, R.L., 1980. Handbook of Water-Soluble Gums and Resins. McGraw-Hill, USA.
5. Gundersen, H.G., 1990. Contrast Medium Composition. Eur. Patent Publ. EP 0 409 351 A1.
6. Johnson K., Stoupis C., Torres G.M., Rosenberg E.B., Ros P.R. Superparamagnetic iron oxide (SPIO) as an oral contrast agent in gastrointestinal (GI) magnetic resonance imaging (MRI): comparison with state-of-the-art computed tomography (CT). Magn. Reson. Imaging. 14:1996;43-49.
7. Montgomery, D.C., 1991. Introduction to Statistical Quality Control. John Wiley & Sons, USA.
8. Remington's Pharmaceutical Sciences., 1985. Mack Publishing, USA.
9. Rubin D.L., Muller H.M., Young S.W., Hunke W.A., Gorman W.G. Optimization of an Oral Magnetic Particle formulation as a gastrointestinal contrast agent for magnetic resonance imaging. Magn. Invest. Radiol. 7:1994;81-86.
10. Stark D.D., Fahlvik A.K., Klaveness J. Abdominal imaging (Review). J. Magn. Reson. Imaging. 3:1993;285-295.
11. Taguchi, G., 1976. Experimental Method. Maruzen, Japan.
12. Tobyn M.J., Johnson J.R., Dettmar P.W. Factors affecting in vitro gastric mucoadhesion: II. Physical properties of polymers. Eur. J. Pharm. Biopharm. 42:1996;56-61.