Role of spontaneous and interleukin-2-induced natural killer cell activity in the cytotoxicity and rejection of Fas+ and Fas- tumor cells

Blood

Volumn 92, Issue 11, 1998, Pages 4248-4255

  Bradley, Mike ^a   Zeytun, Ahmet ^a   Rafi Janajreh, Asimah ^a   Nagarkatti, Prakash S ^a   Nagarkatti, Mitzi ^a  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; INTERLEUKIN 2; POLYINOSINIC POLYCYTIDYLIC ACID;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CELL MEDIATED CYTOTOXICITY; CORRELATION FUNCTION; CYTOTOXIC T LYMPHOCYTE; FLOW CYTOMETRY; KNOCKOUT GENE; LYMPHOKINE ACTIVATED KILLER CELL; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL;

EID: 0032400856     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.11.4248     Document Type: Article

References (27)

1. Trinchieri G: Biology of natural killer cells. Adv Immunol 47:187, 1989
2. Oehler JR, Herberman, RB: Natural cell-mediated cytotoxicity in rats. Effects of immunopharmacological treatments on natural reactivity augmented by polyinosinic polycytidylic acid. Int J Cancer 21:221, 1978
3. Grimm EA, Muzumder A, Zhang HZ, Rosenberg SA; Lymphokine activated killer cells phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin-2-activated autologous human peripheral blood lymphocytes. J Exp Med 155:1823, 1983
4. Podack ER, Hengartner H, Lichtenheld MG: A central role of perforin in cytolysis? Annu Rev Immunol 9:129, 1991
5. Smyth MJ, Trapani JA: Granzymes: Exogenous proteinases that induce target cell apoptosis. Immunol Today 16:202, 1995
6. Kagi D, Ledermann B, Burki K, Zinkernagel RM, Hengartner H: Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu Rev Immunol 14:207, 1996
7. Kojima H, Shinohara N, Hanaoka S, Someya-Shirota Y, Takagaki Y, Ohno H, Saito T, Katayama T, Yagita H, Okumura K, Shinkai Y, Alt FW, Matsuzawa A, Yonehara S, Takayama H: Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes. Immunity 1:357, 1994
8. Glass A, Walsh CM, Lynch DH, Clark WR: Regulation of the Fas lytic pathway in cloned CTL. J Immunol 156:3638, 1996
9. Lee RK, Spielmim J, Zhuo DY, Olsen KJ, Podack ER: Perforin, Fas ligand, and tumor necrosis factor are the major cytotoxic molecules Used by lymphokine-activated killer cells. J Immunol 157:1919, 1996
10. Mule JJ, Shu S, Schwartz SL, Rosenberg SA: Adoptive immuno-therapy of established pulmonary metastasis with LAK cells and recombinant IL-2. Science 225:1487, 1984
11. Walsh CM, Matloubian M, Liu CG, Ueda R, Kurahara CG, Christensen JL, Huang MT, Young JD, Ahmed R, Clark WR: Immune function in mice lacking the perform gene. Proc Natl Acad Sci USA 91:10854, 1994
12. Seth A, Pyle RH, Nagarkatti M, Nagarkatti PS: Expression of the J11d marker on peripheral T lymphocytes of MRL-lpr/lpr mice. J Immunol 141:1120, 1988
13. Rouvier E, Luciani ME Golstein P: Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity. J Exp Med 177:195,1993
14. mel-14. Proc Natl Acad Sci USA 88:7877, 1991
15. Nagarkatti M, Nagarkatti PS, Kaplan AM: Differential effects of BCNU on T cell, macrophage, natural killer and lymphokine-activated killer cell activities in mice bearing a syngeneic tumor. Cancer Immunol Immunother 27:38, 1988
16. Hammond DM, Nagarkatti PS, Gote LR, Seth A, Hassuneh MR, Nagarkatti M: Double-negative T cells from MRL-lpr/lpr mice mediate cytolytic activity when triggered through adhesion molecules and constitutively express perforin gene. J Exp Med 178:2225, 1993
17. Nagarkatti M, Toney D, Nagarkatti PS: Immunomodulation by various nitrosoureas and its effect on the survival of the host bearing a syngeneic tumor. Cancer Res 49:6587, 1989
18. Nagarkatti M, Kaplan AM: The role of suppressor T cells in BCNU-mediated rejection of a syngeneic tumor. J Tmmunol 135:1510, 1985
19. Zeytun A, Hassuneh M, Nagarkatti M, Nagarkatti PS: Fas-Fas-ligand-based interactions between tumor cells and tumor-specific cytotoxic T lymphocytes: A lethal two-way street. Blood 90:1952, 1997
20. Kataoka T, Shinohara N, Takayama H, Kondo S, Yonehara S, Nagai K: Concanamycin A, a powerful tool for characterization and estimation of contribution of perform- and fas-based lytic pathways in cell-mediated cytotoxicity. J Immunol 156:3678, 1996
21. Yang Y, Mercep M, Ware CF, Ashwell JD: Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: Inhibition of Fas ligand expression by retinoic acid and glucocorticoids. J Exp Med 181:1673, 1995
22. Rafi A, Zeytun A, Bradley M, Sponenberg P, Grayson R, Nagarkatti M, Nagarkatti PS: Evidence for the involvement of Fas ligand and perforin in the induction of vascular leak syndrome. J Immunol 161:3077, 1998
23. Oshimi Y, Oda S, Bond Y, Nagata S, Miyazaki S: Involvement of Fas ligand and Fas-mediated pathway in the cytotoxicity of human natural killer cells. J Immunol 157:2909, 1996
24. Lee RK, Spielman J, Zhao DY, Olsen KJ, Podack ER: Perforin, Fas ligand, and tumor necrosis factor are the major cytotoxic molecules used by lymphokine-activated killer cells. J Immunol 157:1919, 1996
25. Yagita H, Hanabuchi S, Asano Y, Tamura T, Nariuchi H, Okumura K: Fas-mediated cytotoxicity - A new immunoregulatory and pathogenic function of Th1 CD4+ T cells. Immunol Rev 146:223, 1995
26. Oshimi Y, Oda S, Honda Y, Nagata S, Miyazaki S, Oshimi Y: Involvement of Fas ligand and Fas-mediated pathway in the cytotoxicity of human natural killer cells. J Immunol. 157:2909, 1996
27. Arase H, Arase N, Saito T: Fas-mediated cytotoxicity by freshly isolated natural killer cells. J Exp Med 1811:235, 1995