Oral administration of polymer-grafted starch microparticles activates gut-associated lymphocytes and primes mice for a subsequent systemic antigen challenge

Vaccine

Volumn 16, Issue 20, 1998, Pages 2010-2017

  Heritage, Philippa L ^a   Underdown, Brian J ^a   Brook, Michael A ^b   McDermott, Mark R ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Microparticles; Mucosal immunity; Vaccine

Indexed keywords

3 (TRIETHOXYSILYL)PROPYL TERMINATED POLYDIMETHYLSILOXANE; HUMAN SERUM ALBUMIN; IMMUNOGLOBULIN G; POLYMER; STARCH; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN SPECIFICITY; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNIZATION; INTRAGASTRIC DRUG ADMINISTRATION; LYMPHOCYTE PROLIFERATION; MICROENCAPSULATION; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; PEYER PATCH; PRIORITY JOURNAL; PROVOCATION TEST; SPLEEN;

ADMINISTRATION, ORAL; ANIMALS; DIMETHYLPOLYSILOXANES; DRUG CARRIERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GASTRIC MUCOSA; HUMANS; IMMUNIZATION; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; LYMPHOCYTES; LYMPHOID TISSUE; MICE; MICE, INBRED BALB C; MICROSPHERES; SERUM ALBUMIN; SILICONES; STARCH;

EID: 0032400668     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0264-410X(98)00085-1     Document Type: Article

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