A nonresonated orthogonally twisted amide

Chemistry Letters

Volumn , Issue 5, 1998, Pages 451-452

  Yamada, Shinji ^a   Nunami, Noriko ^a   Hori, Kayako ^a  

^a OCHANOMIZU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0032396418     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.1998.451     Document Type: Article

References (21)

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13. It has been reported that N-acyl-5-fluorouracils have twisted geometry in amide moiety. See, H. D. Beall, R. J. Prankerd, L. J. Todaro, and K. B. Sloan, Pharm. Res., 10, 905 (1993). A. Jiang, S. Hu, Y. Wang, and Q. Chen, Chem. J. Chin. Uni., 9, 308 (1988).
14. It has been reported that N-acyl-5-fluorouracils have twisted geometry in amide moiety. See, H. D. Beall, R. J. Prankerd, L. J. Todaro, and K. B. Sloan, Pharm. Res., 10, 905 (1993). A. Jiang, S. Hu, Y. Wang, and Q. Chen, Chem. J. Chin. Uni., 9, 308 (1988).
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17. -3. respectively. CCDC-100651.
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19. AM1 calculations were performed with CS MOPAC Pro.
20. The significant disorder in the t-Bu group shows that intermolecular interaction in crystalline state is not to be the factor for the twisted conformation.
21. G. Gilli, V. Bertolasi, F. Bellucci, and F. Ferretti, J. Am. Chem. Soc., 108, 2420 (1986).