Synthesis of Pyrazoloquinolines as Gastric H+/K+-ATPase Inhibitors

Bulletin of the Korean Chemical Society

Volumn 19, Issue 6, 1998, Pages 667-671

  Kalayanov, G D ^a   Hang, S K ^a   Cheon, H G ^a   Lee, S G ^a   Yum, E K ^a   Kim, S S ^a   Choi, J K ^a  

^a Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0032393323     PISSN: 02532964     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Preliminary account of this work was presented at AIMECS 97. Kalayanov G. D.; Rang, S. K.; Cheon, H. G.; Lee, S. G.; Yum, E. K.; Kim, S. S.; Choi, J.-K. AFMC International Medicinal Chemistry Symposium, Seoul (July, 1997); PA-3.
2. On leave of absence from Physical-Chemical Institute, Odessa, Ukraine.
3. Elguero, J. 'Pyrazoles and their Benzo Derivatives.' In Comprehensive Heterocyclic Chemistry; Katritzky, A. R.; Rees, C. W., Eds. Pergamon Press: New York, 1984; Vol. 5, p 278.
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9. Ife, R. J.; Brown, T. H.; Leach, C. A. Eur. Patent 0 259174.
10. The differences in chemical shifts were generally 0.13-0.27 except for α-methylene protons of 4-substituted compounds which were - 0.03-0.09.
11. This peak sometimes appeared as doublet of doublet with small second coupling constant of approximately 1 Hz.
12. Sicker, D. J. Heterocycl. Chem. 1992, 29, 275.
13. Kalayanov, G. D.; Choi, J.-K. Heterocycles 1998, 45, (in press).
14. Cheon, H. G.; Kim, H. J.; Yum, E. K.; Cho, S. Y.; Kim, D. Y.; Yang, S.-I. J. Applied Pharmacol. 1995, 3, 205.