Synthesis of 4-sulfur-substituted (2S,3R)-3-phenylserines by enzymatic resolution. Enantionure precursors for thiamphenicol and florfenicol

Organic Process Research and Development

Volumn 2, Issue 1, 1998, Pages 10-17

  Kaptein, Bernard ^a   Van Dooren, Thei J G M ^a   Boesten, Wilhelmus H J ^a   Sonke, Theo ^a   Duchateau, Alexander L L ^b   Broxterman, Quirinus B ^a   Kamphuis, Johan ^a  

^a DSM RESEARCH   (Netherlands)

^b DSM Fine Chemicals Austria Nfg GmbH & Co KG   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0032338508     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op970045t     Document Type: Article

References (7)

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3. (a) Tyson, R. Chem. Ind. (London) 1988, 118.
4. (b) Nagabhushan, T. L. Eur pat. Appl. 14,437, 1980, and U.S. pat. 4,235,892, 1980 (to Schering).
5. Noyori, R.; Ikeda, T.; Ohkuma, T.; Widhalm, M.; Kitamura, M.; Takaya, H.; Akutagawa, S.; Sayo, N.; Saito, T.; Taketomi, T.; Kumobayashi, H. J. Am. Chem. Soc. 1989, 111, 9134.
6. (a) Ward, R. S. Tetrahedron: Asymmetry 1995, 6, 1475.
7. (b) Noyori, R.; Tokunaga, M.; Kitamura, M. Bull. Chem. Soc. Jpn. 1995, 68, 36.