Development of large-scale syntheses of ropinirole in the pursuit of a manufacturing process

Organic Process Research and Development

Volumn 2, Issue 1, 1998, Pages 3-9

  Hayler, John D ^a   Howie, Simon L B ^a   Giles, Robert G ^a   Negus, Alan ^a   Oxley, Paul W ^a   Walsgrove, Timothy C ^a   Whiter, M ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0032332356     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op970037c     Document Type: Article

References (6)

1. This paper was presented at the launch of Organic Process Research & Development, which was held in London on April 25, 1997.
2. Hayler, J. D.; Howie, S. L. B.; Giles R. G.; Negus, A.; Oxley, P. W.; Walsgrove, T. C.; Walsh, S. E.; Dagger, R. E.; Fortunak J. M.; Mastrocola, A. J. Heterocycl. Chem. 1995, 32, 875.
3. Fortunak, J. M.; Giles, R. G.; Walsgrove, T. C. Eur. Pat. 0300614 A1, 1989; Chem. Abstr. 1989, 110, 212605r.
4. Schmitz, E.; Rieche, A. Chem. Ber. 1956, 89, 1254. Schmitz, E. Chem. Ber. 1958, 91, 1133.
5. Schmitz, E.; Rieche, A. Chem. Ber. 1956, 89, 1254. Schmitz, E. Chem. Ber. 1958, 91, 1133.
6. Giles, R. G.; Walsgrove, T. C. PCT Intl. Appl. WO 91/16306 A1, 1991; Chem. Abstr. 1992, 116, 106086m.