Process for the capture and reuse of the 4,4′-dimethoxytriphenylmethyl group during manufacturing of oligonucleotides

Organic Process Research and Development

Volumn 2, Issue 6, 1998, Pages 415-417

  Guo, Zhiqiang ^a   Pfundheller, Henrik M ^a   Sanghvi, Yogesh S ^a  

^a ISIS PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0032328818     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op980048l     Document Type: Article

References (6)

1. Crooke, S. T. Biotechnology and Genetic Engineering Reviews; Intercept: Newcastle upon Tyne, UK, 1998; Vol. 15, pp 121-157.
2. Soyfer, V. N., Potaman, V. N., Eds. Triple Helical Nucleic Acids; Springer-Verlag: New York, 1996.
3. Eckstein, F., Lilley, D. M., Eds. Catalytic RNA; Springer-Verlag: New York, 1996.
4. Bischofberger, N.; Shea, R. G. In Nucleic Acid Targeted Drug Design; Propst, C. L., Perun, T. J., Eds.; Marcel Dekker: New York, 1992; Chapter 13, pp 579-612.
5. Sanghvi, Y. S. In Vol. 7: DNA and Aspects of Molecular Biology; Kool, E., Ed.; In Comprehensive Natural Product Chemistry; Barton, D. H. R., Nakanishi, K., Eds. in chief; Elsevier Science: Oxford, UK, 1998 (in press).
6. Beaucage, S. L.; Caruthers, M. In Bioorganic Chemistry Nucleic Acids; Hecht, S. M., Ed.; Oxford University Press: New York, 1996; Chapter 2, pp 36-74.