Construction and immunological assessment of Salmonella typhimurium expressing fox sperm LDH-C4

Reproduction, Fertility and Development

Volumn 10, Issue 3, 1998, Pages 225-231

  Bird, Peter ^a,c   Hayes, Christine ^a   De Jersey, James ^a   Bradley, Mark ^b  

^a CSIRO   (Australia)

^b Perth Zoo   (Australia)

^c THERAPEUTIC GOODS ADMINISTRATION   (Australia)

Author keywords

Immunocontraception; LDH C4; Mucosal immunity; Salmonella; Sperm antigens

Indexed keywords

CANIDAE; SALMONELLA; SALMONELLA TYPHIMURIUM; TYPHIMURIUM; VULPES VULPES; ANIMALIA; BACTERIA (MICROORGANISMS);

ANTIBODY; BACTERIUM LIPOPOLYSACCHARIDE; COMPLEMENTARY DNA; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; LACTATE DEHYDROGENASE; SPERM ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; BLOOD LEVEL; CONTROLLED STUDY; FOX; IMMUNITY; IMMUNOCONTRACEPTION; MALE; NONHUMAN; PLASMID; SALIVA LEVEL; SALMONELLA TYPHIMURIUM; SPERM;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES; ANTIGENS; CONTRACEPTION, IMMUNOLOGIC; FOXES; GENE EXPRESSION; IMMUNOGLOBULIN A; ISOENZYMES; L-LACTATE DEHYDROGENASE; MALE; PLASMIDS; RECOMBINANT PROTEINS; SALIVA; SALMONELLA TYPHIMURIUM; SPERMATOZOA; TRANSFECTION;

EID: 0032321630     PISSN: 10313613     EISSN: None     Source Type: Journal    
DOI: 10.1071/R97076     Document Type: Article

References (22)

1. Alexander, N. J., and Bailey, G. (1994). Contraceptive vaccine development. Reprod. Fertil. Dev. 6, 273-80.
2. Beaton, S., ten Have, J., and Bradley, M. P. (1995). Cloning and partial characterization of the cDNA encoding the fox sperm antigen FSA Acr.1 with similarities to the SP-10 antigen. Mol. Reprod. Dev. 40, 242-52.
3. Bradley, M. P. (1994). Experimental strategies for the development of an immunocontraceptive vaccine for the European red fox Vulpes vulpes. Reprod. Fertil. Dev. 6, 307-17.
4. Bradley, M. P., Geelan, A., Leitch, V., and Goldberg, E. (1996). Cloning, sequencing and characterisation of LDH-C4 from a fox testis cDNA library. Mol. Reprod. Dev. 44, 452-9.
5. Bradley, M. P., Hinds, L. A., and Bird, P. H. (1997). A bait-delivered immunocontraceptive vaccine for the European red fox (Vulpes vulpes) by the year 2002. Reprod. Fertil. Dev. 9, 111-16.
6. + for all three chromosomally located systems of DNA restriction and modification. J. Bact. 156, 471-4.
7. Cardenas, L., and Clements, J. (1993). Stability, immunogenicity and expression of foreign antigens in bacterial vaccine vectors. Vaccine 11, 126-35.
8. Cryz, S. J. Jr (1996). Vaccine delivery systems: live attenuated bacterial vaccine vector systems. Vaccine 14, 676-80.
9. Curtiss, R. III (1990). Attenuated Salmonella strains as live vectors for the expression of foreign antigens. In 'New Generation Vaccines'. (Eds G. C. Woodrow and M. M. Levine.) pp. 161-88. (Marcel Dekker Inc.: New York.)
10. Goldberg, E. (1974). Effects of immunisation with LDH-X on fertility. Acta Endocrinol. (Copenh) 78, 202-22.
11. Goldberg, E. (1977). Isozymes in testes and spermatozoa. In 'Isozymes: Current Topics in Biological and Medical Research, Vol. 1'. (Eds M. C. Ratazzi, J. G. Scandalios and G. S. Whitt.) pp. 79-124. (Alan R. Liss, Inc.: New York.)
12. Goldberg, E., Wheat, T. E., Powers, J. E., and Stevens, V. C. (1981). Reduction in fertility in female baboons immunised with lactate dehydrogenase C4. Fertil. Steril. 35, 214-17.
13. Herr, J. C. (1996). Update on the centre for recombinant gamete contraceptive vaccinogens. Am. J. Reprod. Immun. 35, 184-9.
14. Hodgson, A. L. M. (1994). Bacterial vaccine vectors. In 'Immunological Applications to Animal Health and Production'. (Eds P. R. Wood.) pp. 177-86. (CSIRO Australia: Melbourne.)
15. Hoiseth, S. K., and Stocker, B. A. D. (1981). Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines. Nature 291, 238-9.
16. Maniatis, T., Fritsch, E. F., and Sambrook, J. (1982). 'Molecular Cloning - A Laboratory Manual.' (Cold Spring Harbour Laboratory: New York.)
17. McGhee, J. R., Mesteckey, M. T., Dertzbaugh, J. H., Eldridge, M., Hirasawa, and Kiyono, H. (1992). The mucosal immune system: from fundamental concepts to vaccine development. Vaccine 10, 75-88.
18. O'Hern, P. A., Charanjit, B. S., Isahakia, M., and Goldberg, E. (1995). Reversible contraception in female baboons immunised with a synthetic epitope of sperm specific lactate dehydrogenase. Biol. Reprod. 52, 331-9.
19. Srinivasan, J., Tinge, S., Wright, R., Herr, J. C., and Curtiss, R. III (1995). Oral immunisation with attenuated Salmonella expressing human antigen induces antibodies in serum and the reproductive tract. Biol. Reprod. 53, 462-71.
20. Towbin, H., and Gordon, J. (1984). Immunoblotting and dot immunobinding - current status and outlook. J. Immunol. Methods. 72, 313-40.
21. Wheat, T. E., and Goldberg, E. (1977). An allelic variant of the sperm-specific lactate dehydrogenase C4 (LDH-X isozyme in humans). J. Exp. Zool. 202, 425-30.
22. Zhang, X., Lou, Y., Koopman, M., Doggett, T., Tung, K. S. K., and Curtiss, R. III (1997). Antibody responses and infertility in mice following oral immunisation with attenuated Salmonella typhimurium expressing recombinant murine ZP3. Biol Reprod. 56, 33-41.