New biological properties of tert-butyl cephalosporanate sulfones

European Journal of Medicinal Chemistry

Volumn 33, Issue 10, 1998, Pages 755-762

  Veinberg, Grigory ^a   Shestakova, Irina ^a   Grigan, Nora ^a   Musel, Dan ^a   Kanepe, Iveta ^a   Domrachova, Ilona ^a   Grigoryeva, Vera ^a   Zharkova, Olga ^a   Turovskis, Ivars ^a   Kalvinsh, Ivars ^a   Strakovs, Andris ^a   Lukevics, Edmunds ^a  

^a LATVIAN INSTITUTE OF ORGANIC SYNTHESIS   (Latvia)

Author keywords

Antiinflammatory and cytotoxic properties; Aspirin; Basic hydrolysis; Diclofenac; Elastase inhibition; Nitric oxide generation; tert butyl cephalosporanate 1,1 dioxides

Indexed keywords

ACETYLSALICYLIC ACID; CEPHALOSPORANIC ACID DERIVATIVE; DICLOFENAC; ELASTASE; NITRIC OXIDE; SULFONE DERIVATIVE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CATALYSIS; CYTOTOXICITY; DRUG EFFICACY; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME SYNTHESIS; HYDROLYSIS; MOUSE; NONHUMAN; STRUCTURE ANALYSIS;

EID: 0032318195     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(99)80027-0     Document Type: Article

References (19)

1. [1] Dax S.L., Antibacterial Chemotherapeutic Agents, Blackie Academic & Professional, London, 1997, pp. 74-157.
2. [2] Lamotte-Brasseur J., Knox J., Kelly J.A., Charlier P., Fonze E., Diderberg O., Frere J.-M., Biotechnol. Gen. Eng. Rev. 12 (1994) 189-230.
3. [3] Doherty J.B. et al., J. Med. Chem. 33 (1990) 2513-2521.
4. [4] Otani T., Oie S., Matsumoto H., Tempest M., Micetich R.G., Singh R., Yamashita T., PCT Int. Appl. WO 94 01109 (1974); Chem. Abstr. 121 (1994) 57497p.
5. [4] Otani T., Oie S., Matsumoto H., Tempest M., Micetich R.G., Singh R., Yamashita T., PCT Int. Appl. WO 94 01109 (1974); Chem. Abstr. 121 (1994) 57497p.
6. [5] Arrigoni-Martelli E., in: Glynn L.E., Houck J.C., Weissmann J.C. (Eds.), Handbook of Inflammation, Vol. 5, Elsevier, Amsterdam, 1985, pp. 1-25.
7. [6] Alpegiani M., Baici A., Bissolino P., Carminati P., Cassinelli G., Nero S.D., Franceschi G., Orezzi P., Perrone E., Rizzo V., Sacchi V., Eur. J. Med. Chem. 27 (1992) 875-890.
8. [7] Blacklock T.J., Butcher J.W., Sohar P., Lamanec T.R., Grabowski E.J.J., J. Org. Chem. 54 (1989) 3907-3913.
9. [8] Veinberg G.A., Petrulanis L., Grigan N., Turovsky I., Musel D., Lukevics E., Khim. Heterotsikl. Soedin. (1996) 110-114.
10. [9] Grigan N., Musel D., Veinberg G.A., Lukevics E., Synth. Commun. 26 (1996) 1183-1185.
11. [10] Geigy J.R., A.-G. Brit. Pat. (1968) 1132318; Chem. Abstr. 70 (1969) 57455b.
12. [10] Geigy J.R., A.-G. Brit. Pat. (1968) 1132318; Chem. Abstr. 70 (1969) 57455b.
13. [11] Hamilton-Miller J.M.T., Newton G.G.F., Abraham E.P., Biochem. J. 116 (1970) 371-395.
14. [12] Wong J.T.-F., Kinetics of Enzyme Mechanisms, Academic Press, London, 1975.
15. [13] Kerwin Jr. J.F., Lancaster Jr. ER., Feldman P.L., J. Med. Chem. 38 (1995) 4343-4362.
16. [14] Riddell R.J., Clothier R.H., Balls M.Fd., Chem. Toxicol. 24 (1986) 469-471.
17. [15] Unpublished results.
18. [16] Fast D.J., Lynch R.C., Leu R.W., J. Leuckocyt. Biol. 52 (1992) 255-261.
19. [17] Freshney P.J., Culture of Animal Cells (A Manual of Basic Technique), Wiley-Liss, New York, 1994, pp. 296-297.