Accuracy of repeated blood sampling in rats: A new technique applied in pharmacokinetic/pharmacodynamic studies of the interaction between warfarin and co-enzyme Q10

Journal of Pharmacological and Toxicological Methods

Volumn 40, Issue 4, 1998, Pages 191-199

  Zhou, Qingyu ^a   Chan, Eli ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Anticoagulants; Blood coagulation; Blood specimen collection; Co enzyme Q10; Drug interactions; Pharmacokinetic pharmacodynamic modeling; Warfarin

Indexed keywords

BLOOD CLOTTING FACTOR 7; CITRATE SODIUM; UBIDECARENONE; WARFARIN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD CLOTTING; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG INTERACTION; DRUG METABOLISM; HEMATOCRIT; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PROTHROMBIN TIME; RAT; REPRODUCIBILITY; TECHNIQUE;

ANIMALS; ANTICOAGULANTS; ANTIOXIDANTS; BLOOD SPECIMEN COLLECTION; DRUG INTERACTIONS; FACTOR VII; MALE; PROTHROMBIN TIME; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; TIME FACTORS; UBIQUINONE; WARFARIN;

CELL FUSING AGENT VIRUS;

EID: 0032317245     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(99)00005-2     Document Type: Article

References (26)

1. Abbrecht PH, O'Leary TJ, Bettrendt DM (1982) Evaluation of a computer assisted method for individualized anticoagulant therapy: retrospective and prospective studies using a pharmacodynamics mode. Clin Pharmacol Ther 32:129-136.
2. Banfield C, Rowland M (1984) Stereospecific fluorescence high-performance liquid chromatographic analysis of warfarin and its metabolites in plasma and urine. J Pharm Sci 7:1392-1396.
3. Breckenridge AM (1978) Oral anticoagulant drugs: pharmacokinetic aspects. Semin Hematol 15:19-26.
4. Bush E, Trager WF (1983) High-yield synthesis of warfarin and its phenolic metabolites: new compounds. J Pharm Sci 72:830-831.
5. Covell DG, Abbrecht PH, Berman M (1983) The effect of hepatic uptake on the disappearance of warfarin from the plasma of rats: a kinetic analysis. J Pharmacokinet Biopharm 11:127-145.
6. Dyggve H, Lund E (1954) Micromethod for the quantitative determination of plasma prothrombin and proconvertin. Acta Med Scand 150:207-214.
7. Farrow L Mungall D Raskob BG, Hull R (1990) Predicting the daily prothrombin time response to warfarin. Ther Drug Monit 12:246-249.
8. Garten S, Wosilait WD (1972) An analysis of the binding of coumarin anticoagulants of human serum albumin. Comp Gen Pharmacol 3:83-88.
9. Hermodson MA, Barker WM, Link KP (1971) Studies on the 4-hydroxycoumarrins, synthesis of the metabolites and some other derivatives of warfarin. J Med Chem 14:167-169.
10. Hewick DS, McEwen J (1973) Plasma half-lives, plasma metabolites and the anticoagulant efficacies of the enantiomers of warfarin in man. J Pharm Pharmacol 25:458-465.
11. 10 in clinical cardiology: a long-term study. Mol Aspects Med 15(Suppl):s165-175.
12. Lo AC, Chan K, Yeung JH, Woo KS (1992) The effects of Danshen (Salvia miltiorrhiza) on pharmacokinetics and pharmacodynamics of warfarin in rats. Eur J Drug Metab Pharmacokinet 17:257-262.
13. 10 (ubiquinone). Clin Investig 71:8(Suppl): S116-123.
14. Morton RA (1971) Ubiquinones, plastoquinones and vitamins K. Biol Rev 46:47-96.
15. Nagao T, Ibayashi S, Fuji K, Sugimori H, Sadoshima S, Fujishima M (1995) Treatment of warfarin-induced hair loss with ubidecarenone. Lancet 364:1104-1105.
16. Neubauer BL, Bemis KG, Best KL, Goode RL, Hoove DM, Smith GF, Tanzer LR, Merriman RL (1986) Inhibitory effect of warfarin on the metastasis of the PAIII prostatic adenocarcinoma in the rat. J Urol 135:163-166.
17. O'Reilly RA (1974) Studies of the optical enantiomorphs of warfarin in man. Clin Pharmacol Ther 15:424-430.
18. Porter RE, Sawyer WT, Lowenthal DT (1986) Warfarin. In: Applied Pharmacokinetics: Principles of Therapeutic Drug Monitoring. Eds., WE Evans, JJ Schentag, WD Jusko. Vancouver, WA: Applied therapeutics. pp. 1057-1104.
19. Riley V (1960) Adaptation of orbital bleeding technique to rapid serial blood studies. Proc Soc Exp Biol Med 104:751-754.
20. Sancilio LF, Taylor MA, Mathur PP, Crowe JT (1985) Interaction between warfarin and nonsteroidal antiinflammatory drugs (NSAIDs) in rats. Life Sci 36:1041-1045.
21. Sorg DA, Bucker B (1964) A simple method of obtaining venous blood from small laboratory animals. Proc Soc Exp Biol Med 115:1131-1132.
22. Spigsct O (1994) Reduced effect of warfarin caused by ubidecarenone. Lancet 344:1372-1373.
23. Stone SH (1954) Method for obtaining venous blood from the orbital sinus of the rat or mouse. Science 119:100.
24. 10 in aged rat skeletal muscle. Biochem Mol Biol Int. 37:1111-1120.
25. Sutcliff FA, MacNicoll AD, Gibson GG (1987) Aspects of anticoagulation action: a review of the pharmacology, metabolism and toxicology of warfarin and congeners. Q Rev Drug Metab Drug Interact 5:225-272.
26. Toon S, Hopkins KJ, Garstang FM, Aarons L, Sedman A, Rowland M (1987) Enoxacin-warfarin interaction: pharmacokinetic and stereochemical aspects. Clin Pharmacol Ther 42:33-41.