Enzymatic polymerization of dicarboxylic acid and glycol to polyester in solvent-free system

Chemistry Letters

Volumn , Issue 12, 1998, Pages 1285-1286

  Uyama, Hiroshi ^a   Inada, Kojiro ^a   Kobayashi, Shiro ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0032286731     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.1998.1285     Document Type: Article

References (21)

1. S. Kobayashi, S. Shoda, and H. Uyama, "Catalysis in Precision Polymerization," ed by S. Kobayashi, John Wiley & Sons, Chichester (1997), Chap. 8.
2. S. Kobayashi, S. Shoda, and H. Uyama, Adv. Polym. Sci., 121, 1 (1995).
3. S. Kobayashi and H. Uyama, ACS Symp. Ser., 684, 58 (1998).
4. J. S. Wallace and C. J. Morrow, J. Polym. Sci., Polym. Chem. Ed., 27, 2553 (1989).
5. S. Kobayashi and H. Uyama, Makromol. Chem., Rapid Commun., 14, 841 (1993).
6. H. Uyama and S. Kobayashi, Chem. Lett., 1994, 1687.
7. Y.-Y. Linko, Z.-L. Wang, and J. Seppälä, J. Biotechnol., 40, 133 (1995).
8. D. Knani, A. L., Gutman, and D. H. Kohn, J. Polym. Sci., Polym. Chem. Ed., 31, 1221 (1993).
9. H. Uyama and S. Kobayashi, Chem. Lett., 1993, 1149.
10. H. Uyama, K. Takeya, and S. Kobayashi, Bull. Chem. Soc. Jpn., 68, 56 (1995).
11. H. Uyama, K. Takeya, N. Hoshi, and S. Kobayashi, Macromolecules, 28, 7046 (1995).
12. H. Uyama, H, Kikuchi, K. Takeya, and S. Kobayashi, Acta Polymerica, 47, 357 (1996).
13. S. Namekawa, H. Uyama, and S. Kobayashi, Proc. Jpn. Acad., 74B, 65 (1998).
14. R. T. MacDonald, S. K. Pulapura, Y. Y. Svirkin, R. A. Gross, D. L. Kaplan, J. A. Akkara, G. Swift and S. Wolk, Macromolecules, 28, 73 (1995).
15. W. Wie, J. Li, D. Chen, and P. G. Wang, Macromolecules, 30, 6997 (1997).
16. S. Matsumura, K. Mabuchi, and K. Toshima, Macromol. Rapid Commun., 18, 477 (1997).
17. S. Kobayashi, H. Uyama, S. Suda, and S. Namekawa, Chem. Lett., 1997, 105.
18. I. Gill and E. N. Vulfson, J. Am. Chem. Soc., 115, 3348 (1993).
19. This study was orally presented in May 1998: K. Inada, H. Uyama, and S. Kobayashi, Polym. Prepr., Jpn., 47, 248 (1998).
20. A typical run was as follows (entry 4 in Table 1). A mixture of 0.41 g (2.0 mmol) of sebacic acid, 0.18 g of 1,4-butanediol, and 0.10 g of lipase CA were placed in a dried tube under argon and sealed. The tube was kept under gentle stirring at 60°C for 8 h. A small amount of chloroform was added to the mixture and the part of the organic solution was separated by filtration. The filtrate was poured into a large amount of methanol. The resulting precipitates were collected by centrifugation, followed by drying in vacuo to give 0.29 g of the polymer (yield 56%).
21. Lipases CA and MM are immobilized enzymes on polymer beads, which were donated by Novo Nordisk Bioindustry, Ltd. Other lipases were powdery enzymes. Lipases PC and PF were gifts from Amano Pharmaceutical Co. and PPL was purchased from Sigma Chemical Co.