Simultaneous Determination of Phencyclidine and Its Metabolites in Rat Urine by High-Performance Liquid Chromatography

Analytical Sciences

Volumn 14, Issue 5, 1998, Pages 979-982

  Chiba, Ryoko ^a   Fukushi, Megumi ^a   Tanaka, Akira ^a  

^a SHOWA PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Chemiluminescence; High performance liquid chromatography; Phencyclidine; Rat; Tris(2.2 bipyridyl)ruthenium(II); Urinary metabolite

Indexed keywords

AMMONIUM HYDROXIDE; ANESTHETICS; BIOMOLECULES; CHEMILUMINESCENCE; CHLORINE COMPOUNDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUIDS; METHANOL; PHASE SEPARATION; RATING; RATS; RUTHENIUM COMPOUNDS; SILICA;

BIPYRIDYL; CALIBRATION CURVES; CHEMILUMINESCENCE DETECTION; DISPOSABLE CARTRIDGE; PHENCYCLIDINE; SIMULTANEOUS DETERMINATIONS; SOLID-PHASE EXTRACTION; URINARY METABOLITES;

METABOLITES;

EID: 0032281692     PISSN: 09106340     EISSN: None     Source Type: Journal    
DOI: 10.2116/analsci.14.979     Document Type: Article

References (14)

1. E. J. Cone, W. Buchwald and D. Yousefnejad, J. Chromatogr., 223, 331 (1981).
2. B. R. Kuhnert, B. S. Bagaby and N. L. Golden, J. Chromatogr., 276, 433 (1983).
3. M. A. Elsohly, T. L. little, J. M. Mitchell, B. D. Paul, L. D. Mell and J. Lrving, J. Anal. Toxicol., 12, 180 (1988).
4. C. T. Kandiko, S. Brownig, T. Cooper and W. A. Cox, J. Chromatogr., 528, 208 (1990).
5. K. F. Buechler, S. Mori, B. Noar, D. Mcgrath, J. Villela, M. Clancy, A. Shenhav, A. Colleymore, G. Valkirs, T. Lee, J. F. Bruni, M. Walsh, R. Hoffman, F. Ahmuty, M. Nowakowski, J. Buechler, M. Mitchell, D. Boyd, N. Stiso and R. Anderson Clin. Chem., 38, 1678 (1992).
6. T. A. Nieman, in "Chemiluminescence and Photochemical Reaction Detection in Chromatography", ed. J. W. Birks, Chap. 4, VCH, New York, 1989.
7. T. A. Nieman, in "Luminescence Techniques in Chemical and Biochemical Analysis", ed. W. R. G. Baeyens, D. De Keukeler and K. Korkidis, Chap. 17, Marcel Dekker, New York, 1991.
8. J. B. Noffsinger and N. D. Danielson, Anal. Chem., 59, 865 (1987).
9. M. A. Targove and N. D. Danielson, J. Chromatogr. Sci., 28, 505 (1990).
10. J. A. Holeman and N. D. Danielson, J. Chromatogr., 679, 277 (1994).
11. G. M. Greenway, A. W. Knight and P. J. Knight, Analyst [London]. 120, 2543 (1995).
12. K. Uchikura and M. Kirisawa, Anal. Sci., 7, 803 (1991).
13. V. H. Maddox, E. F. Godefroi and R. F. Parcell, J. Med. Chem., 8, 230 (1965).
14. "Comprehensive Study on Assessment of Drug in Bio-materials", Research Report, The Ministry of Health and Welfare, March, 186 (1994).