In vitro inhibition of digestive enzymes by sorghum condensed tannins [Sorghum bicolor L. (Moench)];Inhibition in vitro d'enzymes digestives par les tanins condensés du sorgho [Sorghum bicolor L. (Moench)]

Sciences des Aliments

Volumn 18, Issue 5, 1998, Pages 507-514

  Nguz, Kabwit ^a   Van Gaver, Dirk ^a   Huyghebaert, André ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

amylase; In vitro; Inhibition; Tanin; Trypsine

Indexed keywords

EID: 0032256994     PISSN: 02408813     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. ASQUITH T.N., UHLIG J., MEHANSHO M., PUTMAN L., CARLSON D.M., BUTLER L.G., 1987. Binding of condensed tannins to salivary proline rich-glycoproteins: The role of the carbohydrat. J. Agric. Food Chem., 35, 331-334.
2. BERNFELD P., 1965. Amylases, α et β. In: COLOWICK S.B. et KAPLAN N.O. (eds), Methods in Enzymology. Academic Press, New York, 1, 149-150.
3. BLYTT H.J., GUSKAR T.K., BUTLER L.G., 1988. Antinutritional effects and ecological significance of dietary condensed tannins may not be due to binding and inhibiting digestive enzymes. J. Chem. Ecol., 14, 1455-1465.
4. BUTLER L.G., 1989. Sorghum polyphenols. In: CHEEKE P.R. (ed.), Toxicants from plant origin, 99-132, Academic Press, New York.
5. FEENY P.P., 1969. Inhibitory effect of oak leaf tannins on the hydrolysis of proteins by trypsin. Phytochemistry, 8, 2119-2126.
6. GADAL P. BOUDET A., 1965. Sur l'inhibition des enzymes par les tannins des feuilles de Quercus sessilis Ehrh. Inhibition de la β-amylase. C. R. Acad. Sci. Paris, 260, 4252-4255.
7. GLICK Z., JOSLYN M.A., 1970. Effect of tannic acid and related compounds on the absorption and utilization of proteins in rats. J. Nutr., 400, 516-520.
8. GOLDSTEIN J., SWAIN T., 1965. The inhibition of enzymes by tannins. Phytochemistry, 4, 184-192.
9. GRIFFITHS D.W., 1986. The inhibition of digestive enzymes by polyphenolic compounds. In: FRIEDMAN M. (ed.), Nutritional and Toxicological Significance of Enzyme Inhibitors in Foods. Adv. Exp. Med. Biol., 199, 501-509.
10. KAKADE M.L., RACKIS J.J., McGHEE E., PUSKI G., 1974. Determination of trypsin inhibitor activity of soy products: A collaborative analysis of an improved procedure. Cereal Chem., 51, 376-382.
11. LINEWEAVER H., BURK D., 1934. The determination of enzyme dissociation constants. J. Am. Chem. Soc., 56, 658-666.
12. MEHANSHO H., BUTLER L.G., CARLSON D.M., 1987. Dietary tannins and salivary proline-rich proteins: Interactions, induction and defense mechanisms. Ann. Rev. Nutr., 7, 423-440.
13. NAZCK M., OICKLE D., SOSULKI F., SHAHIDI F., 1994. Condensed tannins in hulls. J. Agric. Food Chem., 42, 2196-2200.
14. NGUZ K., de MEY L., HUYGHEBAERT A., 1994. Evaluation de la biodégradation des tanins condensés du sorgho [Sorghum bicolor L. (Moench)] par dosage des proanthocyanidines et des flavane-3-ols. Sci. Aliments, 14, 51-59.
15. NGUZ K., HUYGHEBAERT A., 1998. Effet de la teneur en tanins sur la digestibilté in vitro des protéines de variétés africaines de sorgho [Sorghum bicolor L. (Moench)]. Sci. Aliments., 18, 293-300.
16. OH H.I., HOFF J.E., 1986. Effect of condensed tannins on the in vitro activity of digestive proteases and activation of their zymogens. J Food Sci., 51, 577-580.
17. RAO B.S.N., PRAVABHATHI T., 1982. Tannin content of foods commonly consumed in India and its influence on ionisable iron. J. Sci. Food Agric., 33, 89-96.
18. SALUNKHE D.K., CHAVAN J.K., KADAM S.S., 1990. Dietary Tannins: Consequences and Remedies. CRC Press, Boca Raton, Florida.
19. SPENCER C.M., CAI Y., MARTIN R., GAFFNEY S.H., GOULDING P.N., MAGNOLATO D., LILLEY T.H., HASLAM E., 1988. Polyphenol complexation - Some thoughts and observations. Phytochemistry, 27, 2397-2409.
20. SPIES J.R., 1957. Colorimetric procedures for amino acids. In: COLOWICK S.B. et KAPLAN N.O. (eds), Methods in Enzymology. Academic Press, New York, 3, 468-471.
21. STAUFFER E.C., 1989. Enzyme assays for food scientists. Van Nostrand Reinhold, New York.
22. STRUMEYER D.H., MALIN M.J., 1969. Identification of amylase inhibitor from seeds of Leoti sorghum. Biochim. Biophys. Acta, 184, 643-645.
23. TAMIR M., ALUMOT E., 1969. Inhibition of digestive enzymes by condensed tannins from green gram and ripe carobs. J. Sci. Food Agric., 20, 199-202.
24. YAN Q., BENNICK A., 1995. Identification of histatins as tannin-binding proteins in human saliva. Biochem. J., 311, 341-347.