Suppression of nicotine intake during ad libitum cigarette smoking by high-dose transdermal nicotine

Journal of Pharmacology and Experimental Therapeutics

Volumn 287, Issue 3, 1998, Pages 958-962

  Benowitz, Neal L ^a  

^a SAN FRANCISCO GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON MONOXIDE; CARBOXYHEMOGLOBIN; NICOTINE; NICOTINIC AGENT;

ADULT; ARTICLE; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; HUMAN; INTRADERMAL DRUG ADMINISTRATION; MALE; METABOLISM; METHODOLOGY; MIDDLE AGED; SINGLE BLIND PROCEDURE; SMOKING; SMOKING CESSATION; AREA UNDER THE CURVE; CIGARETTE SMOKING; DATA ANALYSIS; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG MEGADOSE; HUMAN EXPERIMENT; HYPOTHESIS; NORMAL HUMAN; PRIORITY JOURNAL; SMOKING HABIT; SUBSTITUTION THERAPY;

ADMINISTRATION, CUTANEOUS; ADULT; CARBON MONOXIDE; CARBOXYHEMOGLOBIN; CROSS-OVER STUDIES; HUMANS; MALE; MIDDLE AGED; NICOTINE; NICOTINIC AGONISTS; SINGLE-BLIND METHOD; SMOKING; SMOKING CESSATION;

EID: 0032253783     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Balfour DJ (1994) Neural mechanisms underlying nicotine dependence. Addiction 89:1419-1423.
2. Benowitz NL (1993) Nicotine replacement therapy: What has been accomplishedcan we do better? Drugs 45:157-170.
3. Benowitz NL (1995) Clinical pharmacology of transdermal nicotine. EUT J Pharm Biopharm 41:168-174.
4. Benowitz NL and Jacob P III (1985) Nicotine renal excretion rate influences nicotine intake during cigarette smoking. J Pharmacol Exp Ther 234:153-155.
5. Benowitz NL and Jacob P III (1990) Intravenous nicotine replacement suppresses nicotine intake from cigarette smoking. J Pharmacol Exp Ther 254:1000-1005.
6. Benowitz NL, Jacob P III, Denaro C and Jenkins R (1991) Stable isotope studies (if nicotine kinetics and bioavailability. Clin Pharmacol Ther 49:270-277.
7. Benowitz NL, Jacob P III and Savanapridi C (1987) Determinants of nicotine intake while chewing nicotine polacrilex gum. Clin Pharmacol Ther 41:467-473.
8. Benowitz NL, Zevin S and Jacob P III (1997) Sources of variability in nicotine and cotinine levels with use of nicotine nasal spray, transdermal nicotine, and cigarette smoking. Br J Clin Pharmacol 43:259-267.
9. Dale LC, Hurt RD, Offord KP, Lawson GM, Croghan IT and Schroeder DR (199£) High-dose nicotine patch therapy: Percentage of replacement and smoking cessation. JAMA 274:1353-1358.
10. Dixon WJ (ed). (1992) BMDP Statistical Software, pp. 521-564, University of California Press, Los Angeles.
11. Fiore MC, Smith SS, Jorenby DE and Baker TB (1994) The effectiveness of thî nicotine patch for smoking cessation: A meta-analysis. JAMA 271:1940-1947.
12. Foulds J, Stapleton J, Feyerabend C, Vesey C, Jarvis M and Russell MAH (1992) Effect of transdermal nicotine patches on cigarette smoking: A double blind crossover study. Psychopharmacology 106:421-427.
13. Gourlay SG and Benowitz NL (1997) Arteriovenous differences in plasma concentration of nicotine and catecholamines and related cardiovascular effects afte smoking, nicotine nasal spray, and intravenous nicotine. Clin Pharmacol Thee 62:453-463.
14. Hartman N, Leong GB, Glynn SM, Wilkins JN and Jarvik ME (1991) Transdermal nicotine and smoking behavior in psychiatric patients. Am J Psychiatry 148:374375.
15. Henningneid JE (1995) Nicotine medications for smoking cessation. N Engl J Mec' 333:1196-1197.
16. Henningfield JH, London ED and Benowitz NL (1990) Arterial-venous differences ir plasma concentrations of nicotine after cigarette smoking (Ltr). JAMA 263:20492050.
17. Hurt RD, Lauger GG, Offord KP, Kottke TE and Dale LC (1990) Nicotinereplacement therapy with use of a transdermal nicotine patch-a randomized double-blind placebo-controlled trial. Mayo Clin Proc 65:1529-1537.
18. Jacob P III, Wilson M and Benowitz NL (1981) Improved gas Chromatographie method for determination of nicotine and cotinine in biologic fluids. J Chromatogr 222:61-70.
19. Jacob P III, Yu L, Wilson M and Benowitz NL (1991) Selected ion monitoring method for determination of nicotine, cotinine, and deuterium-labeled analogs: Absence of an isotope effect in the clearance of (S)-nicotine-3'-3'-d2 in humans. Biol Mass Spectrom 20:247-252.
20. James JR, Villanueve HF, Johnson JH, Arezo S and Rosecrans JA (1994) Evidence that nicotine can acutely desensitize central nicotinic acetylcholinergic receptors. Psychopharmacology (Berl) 114:456-462.
21. Jorenby DE, Smith SS, Fiore MC, Hurt RD, Offord KP, Croghan IT, Hays JT and Lewis SF (1995) Varying nicotine patch dose and type of smoking cessation counseling. JAMA 274:1347-1352.
22. Levin ED, Westman EC, Stein RM, Carnahan E, Sanchez M, Herman S, Behm FM and Rose JE (1994) Nicotine skin patch treatment increases abstinence, decreases withdrawal symptoms, and attenuates rewarding effects of smoking. J Clin Psychopharmacol 14:41-49.
23. Pickworth WB, Bunker EB and Henningfield JE (1994) Transdermal nicotine: Reduction of smoking with minimal abuse liability. Psychopharmacology 115:9-14.
24. Sachs DP, Benowitz NL, Bostrum AG and Hansen MD (1995) Percent serum replacement and success of nicotine patch therapy. Am J Resp Crit Care Med A688.
25. Tang JL, Law M and Wald N (1994) How effective is nicotine replacement therapy in helping people to stop smoking? Br Med J 308:21-26.
26. Tonnesen P, Fryd V, Hansen M, Helsted J, Gunnersen AB, Forchammer H and Stockner M (1988) Effect of nicotine chewing gum in combination with group counseling on the cessation of smoking. N Engl J Med 318:15-18.
27. Transdermal Nicotine Study Group: Transdermal nicotine for smoking cessation. J Am MedAssn 266:3133-3138.
28. Zevin S, Jacob P III and Benowitz NL (1998) Dose-related cardiovascular and endocrine effects of transdermal nicotine. Clin Pharmacol Ther 64:87-95.