The incorporation of various porphyrins into blood cells measured via flow cytometry, absorption and emission spectroscopy

Acta Biochimica Polonica

Volumn 45, Issue 3, 1998, Pages 833-845

  Ion, Rodica Mariana ^a   Planner, Alfons ^b   Wiktorowicz, Krzysztof ^c   Fra̧ckowiak, Danuta ^b  

^a Photochemistry Department   (Romania)

^b POZNAN UNIVERSITY OF TECHNOLOGY   (Poland)

^c POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Cytometry; Fluorescence; Granulocytes; Lymphocytes; Photodynamic therapy; Porphyrins

Indexed keywords

COLORING AGENT; PORPHYRIN;

ARTICLE; BLOOD; BLOOD CELL; FLOW CYTOMETRY; HUMAN; METABOLISM; SPECTROFLUOROMETRY; ULTRAVIOLET SPECTROPHOTOMETRY;

BLOOD CELLS; COLORING AGENTS; FLOW CYTOMETRY; HUMANS; PORPHYRINS; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0032253115     PISSN: 0001527X     EISSN: None     Source Type: Journal    
DOI: 10.18388/abp.1998_4279     Document Type: Article

References (34)

1. West, C.M. & Moore, J.W. (1989) Flow cytometric analysis of intercellular haematoporphyrin derivative in human tumour cells and multicellular spheroids. Photochem. Photobiol. 50, 665-669.
2. Gluck, S., Chadderton, A. & Ho, A.D. (1996) The selective uptake of benzoporphyrin derivative mono-acid ring. A results in differential cell kill of multiple melanoma cells in vitro. Photochem. Photobiol. 63, 846-853.
3. Wiktorowicz, K., Niedbalska, M., Planner, A. & Fra̧ckowiak, D. (1995) Incorporation of stilbazolium merocyanines into human leukocytes measured by flow cytometry. Acta Biochim. Polon. 42, 333-338.
4. Fra̧ckowiak, D., Wiktorowicz, K., Cofta, J., Niedbalska, M. & Latosińska, M. (1995) Incorporation of stilbazolium merocyanines into resting and stimulated mononuclear leukocytes. Acta Biochim. Polon. 42, 61-68.
5. Berg, K., Western, A., Bommer, J.C. & Moan, J. (1990) Intracellular localization of sulfonated meso-tetraphenylporphyrins in a human carcinoma cell line. Photochem. Photobiol. 52, 481-487.
6. Moan, J., Peng, Q., Evensen, J.F., Berg, K., Western, A. & Rimington, C. (1987) Photosensitizing efficiencies, tumor and cellular uptake of different photosynthetizing drugs relevant for photodynamic therapy of cancer. Photochem. Photobiol. 46, 713-721.
7. Kessel, D., Thomson, P., Saatio, K. & Nauwi, K.D. (1987) Tumor localization and photosensitization by sulfonated derivatives of TPP. Photochem. Photobiol. 45, 787-790.
8. Reddi, E. & Jori, G. (1988) Steady state and time resolved spectroscopic studies of photodynamic sensitizers, porphyrins and phtalocyanines. Rev. Chem. Intermed. 10, 241-268.
9. Ricchelli, F. (1995) Photophysical properties of porphyrins in biological membranes. J. Photochem. Photobiol. B: Biol. 29, 109-118.
10. Zankevich, E., Sagun, E., Knyukshto, V., Shulga, A., Mironov, A., Efremova, O., Bonnett, R., Songca, S.P. & Kassem, M. (1966) Photophysical and photochemical properties of potential porphyrin and chlorin photosensitizer. J. Photochem. Photobiol. B: Biol. 33, 171-180.
11. Ion, R.M., Teodorescu, L., Mocanu, E., Badica, D., Culetu, H. & Belsadski, M. (1988) Porphyrinic sensitizers used in photooxidation reactions. Rev. Chim. (Bucharest) 39, 132-135.
12. Rousseau, K. & Dolphin, D. (1974) A purification of meso-tetraarylporphyrin. Tetrah. Lett. 48, 4251-4254.
13. Barnett, G.H., Hudson, M.F. & Smith, K.M. (1973) Meso-tetraphenylporphyrin purification. Tetrah. Lett. 30, 2887-2888.
14. Abraham, R.J., Hawkes, G.E., Hudson, M.F. & Smith, K.M. (1975) The nuclear magnetic resonance spectra of porphyrins. Part X. Carbon-13 NMR spectra of some meso-tetraarylporphyrins and their metal chelates. J. Chem. Soc. Perkin Trans. II 3, 204-211.
15. Ion, R.M., Teodorescu, L., Mandravel, C., Volanski, E. & Hillebrand, M. (1990) The degradation of the porphyrinic photosensitizers used in the photochemical conversion of solar energy. Rev. Chim. (Bucharest) 41, 129-132.
16. Berg, K. (1990) Cellular Uptake and Photosynthetizing Effects of Porphyrins and Phtalocyanines. Ph.D. Thesis, Oslo, 22 pp.
17. Ion, R.M. (1993) The spectrophotometric study of the photodegradation reaction of tetraphenylporphyrine. The solvent effect. Rev. Chim. (Bucharest) 44, 957-959.
18. Carter, N.P. & Meyer, E.W. (1990) Introduction to Principles of Flow Cytometry. Flow Cytometry. A Practical Approach (Ormerod, M.G., ed.) pp. 1-28, Oxford University Press, Oxford, New York, Tokyo.
19. Fra̧ckowiak, D., Dudkowiak, A., Cegielski, R., Planner, A. & Schulz, C. (1995) Optical properties of the purple bacterium reaction centres immobilized in polymer film. Photosynthetica 31, 283-299.
20. Berg, K., Steen, H.B., Winkelman, J.W. & Moan, J. (1992) Synergistic effects of photoactivated tetra(4-sulfonatophenyl)porphine and nocodazole on microtubule assembly, accumulation of cells in mitosis and cell survival. J. Photochem. Photobiol. B: Biol 13, 59-70.
21. Wessels, J., Strauss, W., Seidlitz, H.K., Ruck, A. &. Schneckenburger, H. (1992) Intracellular localization of meso-tetra porphine tetra-sulfonate probed by time resolved and microscopic fluorescence spectroscopy. J. Photochem. Photobiol. B: Biol. 12, 275-284.
22. Chow, E.F.A., Dolphin, D., Paine, J.P., III, McGarvey, D., Pottier, R. & Truscott, T.G. (1988) The excited states of covalently-linked dimeric porphyrins. I. The excited singlet states. J. Photochem. Photobiol. B: Biol. 2, 253-263.
23. Ion, R.M. (1997) Spectral properties of the porphyrins incorporated into human blood. International Symposium on Photodynamic Therapy, Wrocław, 1997.
24. Borokov, V.V., Anikin, M., Wasa, K. & Sakata, Y. (1996) Structurally controled porphyrin- aggregation process in phospholipid membranes. Photochem. Photobiol. 63, 477-482.
25. Cubeddu, R., Ramponi, R. & Bottiroli, G. (1987) Disaggregation effects on hematoporphyrin in the presence of surfactants at different concentrations: Temperature dependence. Proc. SPIE 701, 316-319.
26. Moan, J. & Sommer, S. (1993) Uptake of the components of hematoporphyrin derivatives by cells and tumors. Cancer Lett. 21, 167-174.
27. Winkelman, J.W., Arad, D. & Kimel, S. (1993) Stereochemical factors in the transport and binding of photosensitizers in biological systems and in photodynamic therapy. J. Photochem. Photobiol. B: Biol. 18, 181-189.
28. Ion, R.M. (1993) Spectrophotometric study of the photodegradation reaction of tetra-arylporphyrins. The meso-substituent effects. Rev. Chim. (Bucharest) 44, 431-434.
29. Mandravel, C., Ion, R.M. & Alstanei, A.M. (1992) The hydrogen bond and stability of porphyrin derivatives - cetylic alcohol - carbon tetrachloride systems, (II). Anal. Univ. Buc.: Chimie I, 59-62.
30. Kessel, D. & Cheng, M.L. (1985) Biological and biophysical properties of the tumor - localizing component of hematoporphyrin. Cancer. Lett. 45, 3052-3057.
31. Dougherty, T.J. (1985) Photodynamic Therapy; in Methods in Porphyrin Photosensitization (Kessel, D., ed.) pp. 313-328, Plenum, New York.
32. Moan, J. & Sommer, S. (1984) Action spectra for hematoporphyrin and Photofrin II with respect to sensitization of human cells in vitro to photoinactivation. Photochem. Photobiol. 40, 631-634.
33. Dougherty, T. (1987) Photosensitizers: Therapy and detection of malignant tumors. Photochem. Photobiol. 45, 879-889.
34. Moan, J., Christensen, T. & Jacobsen, P.B. (1984) Porphyrin - sensitized photoinactivation of cells in vitro; in Porphyrin Localization and Treatment of Tumors (Doiron, D.R. & Gomer, C.J., eds.) pp. 419-442, Alan R. Liss, New York.