Radiation-induced enterocolitis: Basic and applied science

European Journal of Surgery, Supplement

Volumn 164, Issue 582, 1998, Pages 85-89

  Szabo, Sandor ^b   Sandor, Zsuzsa ^c   Vincze, Aron ^c   Gombos, Zoltan ^c   Mohiuddin, Ahmed ^a   Viravathana, Thavinsakdi ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VA LONG BEACH HEALTHCARE SYSTEM   (United States)

^c Pathol and Lab Medicine Service VA Medical Center ^*

Author keywords

Abdominal radiation; Animal models; bFGF; Enterocolitis; Sucralfate

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; SUCRALFATE; FIBROBLAST GROWTH FACTOR 2; GASTROINTESTINAL AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASCENDING COLON; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; ENTEROCOLITIS; EROSION; ILEUM; INTESTINE ULCER; INTRAGASTRIC DRUG ADMINISTRATION; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RADIATION INJURY; RAT; ANIMAL; PATHOLOGY; RADIATION DOSE; RADIATION RESPONSE; SPRAGUE DAWLEY RAT;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, RADIATION; ENTEROCOLITIS; FIBROBLAST GROWTH FACTOR 2; GASTROINTESTINAL AGENTS; RADIATION DOSAGE; RADIATION INJURIES, EXPERIMENTAL; RATS; RATS, SPRAGUE-DAWLEY; SUCRALFATE;

EID: 0032250481     PISSN: 1102416X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. 1. Babb RR. Radiation proctitis: A review. Am J Gastroenterol 1996; 91: 1309-1311.
2. 2. Crook J, Esche B, Futter N. Effect of pelvic radiotherapy for prostate cancer on bowel, bladder and sexual function: The patient's perspective. Urology 1996; 47: 387-394.
3. 3. Delaney JP, Bonsack M. Acute radiation enteritis in rats: Bile salts and trypsin. Surgery 1992; 112: 587-592.
4. 4. Delaney JP, Kimm GE, Bonsack ME. The influence of lumenal pH on the severity of acute radiation enteritis. Int J Radiat Biol 1992; 61: 381-386.
5. 5. Dubray BM, Thames HD. Chronic radiation damage in the rat rectum: An analysis of the influences of fractionation, time and volume. Radiother Oncol 1994; 33: 41-47.
6. 6. Empey LR, Papp JD, Jewell LD, Fedorak RN. Mucosal protective effects of vitamin E and misoprostol during acute radiation-induced enteritis in rats. Dig Dis Sci 1992; 37: 205-214.
7. 7. Folkman J, Szabo S, Stovroff M, et al. Duodenal ulcer: discovery of a new mechanism and development of angiogenic therapy that accelerates healing. Ann Surg 1991; 214: 414-426.
8. 8. Henriksson R, Franzen L, Littbrand B. Prevention and therapy of radiation-induced bowel discomfort. Scand J Gastroenterol 1992; 191: 7-11.
9. 9. Kitajima M, Nakamura M, Tsuchiya M. Effect of basic fibroblast growth factor on formation of microvascular architecture in ulcer regenerative tissue. Gastroenterology 1993; 104: A119.
10. 10. Kochuras R, Sharma SC, Gupta BB, Mehta SK. Rectal sucralfate in radiation proctitis. Lancet 1988; 2: 400.
11. 11. Kumar V, Cotran RS, Robbins SL (eds) Basic Pathology. 6th edition. Philadelphia, PA: W. B. Saunders Co, 1997.
12. 12. Nagata M, Vincze A, Kusstatscher S, Szabo S. The effect of sucralfate on experimental ulcerative colitis. Gastroenterology 1995; 108: A173.
13. 13. Ogihara T, Kusstatscher S, Sandor Zs, Nagata M, Sato N, Szabo S. Effect of sucralfate on the colonic mucosal hypoxia in the iodoacetamide-induced ulcerative colitis in rats. Gastroenterology 1995; 108: A887.
14. 14. Potten CS, Henry JH, (eds) Radiation and the gut. Amsterdam: Elsevier, 1995.
15. 15. Rose P, Halter S, Su CM. The effect of indomethacin on acute radiation induced gastrointestinal injury: A morphologic study. J Surg Oncol 1992; 9: 231-238.
16. 16. Rubin E, Farber JL, (eds) Essential Pathology. 2nd edition, Philadelphia, PA: J. B. Lippincott Company, 1995.
17. 17. Saclarides TJ, King DG, Franklin JL, Doolas A. Formalin instillation for refractory radiation-induced hemorrhagic proctitis. Dis Col Rect 1996; 39: 196-199.
18. 18. Sandor Zs, Nagata M, Kusstatscher S, Szabo S. New animal model of ulcerative colitis associated with depletion of glutathione and protein SH alkylation. Gastroenterology 1994; 106: A766.
19. 19. Satoh H, Takami K, Kato K, Folkman J, Szabo S. Effect of bFGF and its mutein on healing of colonic ulcers induced by N-ethylmaleimide in rats. Gastroenterology 1990; 98: A203.
20. 20. Stovroff M, Vattay P, Marino B, Szabo S, Folkman J. Healing of experimental gastritis by oral fibroblast growth factor. Surg For 1991 1991; 42: 174-175.
21. 21. Szabo S. Toward a direct treatment of ulcer disease -new mechanistic approach to ulcer prevention and therapy in the gastrointestinal tract. Jpn Arch Int Med 1994; 41: 47-55.
22. 22. Szabo S, Folkman J, Vattay P, et al. Accelerated healing of duodenal ulcers by oral administration of mutein of fibroblast growth factor in rats. Gastroenterology 1994; 106: 1106-1111.
23. 23. Szabo S, Folkman J, Vattay P, Morales RE, Kato K. Duodenal ulcerogens: Effect of FGF on cysteamine-induced duodenal ulcer. In: Halter F, Garner A, Tytgat GNJ, (eds) Ulcer healing. London: Kluwer Academic Pub., 1991: 139-150.
24. 24. Szabo S, Kovacs K. Causes and mechanisms of cell and tissue injury in endocrine glands. In: K Kovacs, SL Asa, (eds). Functional Endrocrine Pathology, 2nd edition, Boston, MA: Blackwell Scientific Publications, 1991: 914-926.
25. 25. Szabo S, Kusstatscher S, Stovroff M. Role of bFGF and angiogenesis in ulcer healing and the treatment of gastritis. In: Domschke W, Konturek SJ, (eds). The Stomach. Berlin: Springer-Verlag, 1993: 193-197.
26. 26. Szabo S, Vattay P, Scarbrough E, Folkman J. Role of vascular factors, including angiogenesis, in mechanisms of action of sucralfate. Am J Med 1991; 91: 158S-160S.
27. 27. Tominaga K, Arakawa T, Fukuda T, et al. Effect of sucralfate on location of basic fibroblast growth factor in chronic gastric ulcers in rats. Gastroenterology 1993; 104: A649.
28. 28. Wiseman JS, Senagore AJ, Chaudry IH. Methods to prevent colonic injury in pelvic radiation. Dis Col Rect 1994; 37: 1090-1094.