Murine endothelia do not express MHC class II I-Eα subunit and differentially regulate I-Aα expression along the vascular tree

Endothelium: Journal of Endothelial Cell Research

Volumn 6, Issue 2, 1998, Pages 83-93

  Karasin, Alexander ^a   Macvilay, Sinarack ^a   Hart, Michael N ^a   Fabry, Zsuzsanna ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Interferon ; Interleukin 10; Large vessel endothelium; MHC Class II; Microvessel endothelium

Indexed keywords

MURINAE;

ANIMAL; AORTA; ARTICLE; BAGG ALBINO MOUSE; BRAIN; CAPILLARY; FEMALE; GENE; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; T LYMPHOCYTE; VASCULAR ENDOTHELIUM; VASCULARIZATION;

ANIMALS; AORTA; BRAIN; CAPILLARIES; ENDOTHELIUM, VASCULAR; FEMALE; GENE EXPRESSION REGULATION; GENES, MHC CLASS II; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; T-LYMPHOCYTES; TRANSCRIPTION, GENETIC;

EID: 0032248460     PISSN: 10623329     EISSN: None     Source Type: Journal    
DOI: 10.3109/10623329809072195     Document Type: Article

References (41)

1. Baltimore, D., and Smoler, D. (1971). Primer requirement and template specificity of the DNA polymerase of RNA tumor viruses. Proc. Natl. Acad. USA 68, 1507-1511.
2. Batten, P., Yacoub, M. H., and Rose, M. L. (1996). Effect Of Human Cytokines (Ifn-Gamma, Tnf-Alpha, 11-1-Beta, I1-4) On Porcine En Cells - Induction Of Mhc and Adhesion Molecules and Functional Significance Of These Changes. Immunology 87, 127-133.
3. Benoist, C., and Mathis, D. (1990). Regulation of major histocompatibility complex class-II genes: X, Y and other letters of the alphabet. Ann. Rev. Immunol. 8, 681-715.
4. Bi, Z., Barna, M., Komatsu, T., and Reiss, C. S. (1995). Vesicular stomatitis virus infection of the central nervous system activates both innate and acquired immunity. J. Virol. 69, 6466-6472.
5. Bohme, J., Schuhbaur, B., Kanagawa, O., Benoist, C., and Mathis, D. (1990). MHC-linked protection from diabetes dissociated from clonal deletion of T cells. Science 249, 293-295.
6. Bourdoulous, S., Bensaid, A., Martinez, D., Sheikboudou, C., Trap, I., Strosberg, A. D., and Couraud, P. O. (1995). Infection of bovine brain microvessel En cells with Cowdria ruminantium elicits IL-1 beta, -6, and -8 mRNA production and expression of an unusual MHC class II DQ alpha transcript. J. Immunol. 154, 4032-4038.
7. Bourdoulous, S., Durieu-Trautmann, O., Strosberg, A. D., and Couraud, P. O. (1993). Catecholamines stimulate MHC class I, class II, and invariant chain gene expression in brain En through different mechanisms. J. Immunol. 150, 1486-1495.
8. Bravery, C. A., Batten, P., Yacoub, M. H., and Rose, M. L. (1995). Direct Recognition Of Sla- and Hla-Like Class Ii Antigens On Porcine Endothelium By Human T Cells Results In T Cell Activation and Releases Of Interleukin-2. Transplantation 60, 1024-1033.
9. Cannella, B., Aquino, D. A., and Raine, C. S. (1995). MHC II expression in the CNS after long-term demyelination. J. Neuropathol. Exp. Neurol. 54, 521-530.
10. de Vries, J. E. (1995). Immunosuppressive and anti-inflammatory properties of interleukin 10. Ann. Med. 27, 537-541.
11. de Waal Malefyt, R., Abrams, J., Bennett, B., Figdor, C. G., and de Vries, J. E. (1991). Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174, 1209-1220.
12. DeBault, K. J., Henriquez, M., Hart, M. N., and Cancilla, P. A. (1981). Cerebral microvessel derived cells in tissue culture. II. Establishment, identification, and preliminary characterization of an endothelial cell line. In Vitro 17, 480-485.
13. Dore-Duffy, P., Balabanov, R., Washington, R., and Swanborg, R. H. (1994). Transforming growth factor beta 1 inhibits cytokine-induced CNS endothelial cell activation. Mol. Chem. Neuropathol. 22, 161-175.
14. Epperson, D. E., and Pober, J. S. (1994). Antigen-presenting function of human endothelial cells. Direct activation of resting CD8 T cells. J. Immunol. 153, 5402-5412.
15. Fabry, Z., Raine, C. S., Hart, M. N. (1994) Nervous tissue as an immune compartment: the dialect of the immune response in the CNS. Immunol. Today 15 (5) 218-224.
16. Fabry, Z., Sandor, M., Gajewski, T. F., Herlein, J. A., Waldschmidt, M. M., Lynch, R. G., and Hart, M. N. (1993). Differential activation of Th1 and Th2 CD4+ cells by murine brain microvessel endothelial cells and smooth muscle/pericytes. J. Immunol. 151, 38-47.
17. Huynh, H. K., and Dorovini-Zis, K. (1993). Effects of interferon-gamma on primary cultures of human brain microvessel endothelial cells. Am. J. Pathol. 142, 1265-1278.
18. Huynh, H. K., Oger, J., and Dorovinizis, K. (1995). Interferon-Beta Downregulates Interferon-Gamma-Induced Class Ii Mhc Molecule Expression and Morphological Changes In Primary Cultures Of Human Brain Microvessel Endothelial Cells. J. Neuroimmunol. 60, 63-73.
19. Kariuki Njenga, M., and Dangler, C. A. (1995). Endothelial MHC class II antigen expression and endarteritis associated with Marek's disease virus infection in chickens. Vet. Pathol. 32, 403-411.
20. Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K., and Muller, W. (1993) Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75, 263-274.
21. Krco, C. J., Wassom, D. L., Abramson, E. J., and David, C. S. (1983). Cloned T cells recognize Trichinella spiralis antigen in association with an Ek beta Ek alpha restriction element. Immunogenetics 18, 435-444.
22. Linke, A. T., and Male, D. K. (1994). Strain-specific variation in constitutive and inducible expression of MHC class II, class I and ICAM-1 on rat cerebral endothelium. Immunology 82, 88-94.
23. Moore, S. A., Spector, A. A., and Hart, M. N. (1988). Eicosanoid metabolism in cerebromicrovascular endothelium. Am. J. Physiol. 254, 37-44.
24. Nishimoto, H., Kikutani, H., Yamamura, K., and Kishimoto, T. (1987). Prevention of autoimmune insulitis by expression of I-E molecules in NOD mice. Nature 328, 432-434.
25. Oliveira, D. B., Blackwell, N., Virchis, A. E., and Axelrod, R. A. (1985). T helper and T suppressor cells are restricted by the A and E molecules, respectively, in the F antigen system. Immunogenetics 22, 169-175.
26. Page, C., Rose, M., Yacoub, M., and Pigott, R. (1992). Antigenic heterogeneity of vascular endothelium. Am. J. Pathol. 141, 673-683.
27. Pardridge, W. M., Yang, J., Buciak, J., and Tourtellotte, W. W. (1989). Human brain microvascular DR-antigen. J. Neurosci. Res. 23, 337-341.
28. Pugliatti, L., Derre, J., Berger, R., Ucla, C., Reith, W., and Mach, B. (1992). The genes for MHC class II regulatory factors RFX1 and RFX2 are located on the short arm of chromosome 19. Genomics 13, 1307-1310.
29. Reder, A. T., Lascola, C. D., Flanders, S. A., Maimone, D., Jensen, M. A., Skias, D. D., and Lancki, D. W. (1993). Astrocyte cytolysis by MHC class II-specific mouse T cell clones. Transplantation 56, 393-399.
30. Reith, W., Steimle, V., Durand, B., Kobr, M., and Mach, B. (1995). Regulation of MHC class II gene expression. Immunobiology 193, 248-253.
31. Sahagun, G., Moore, S. A., Fabry, Z., Schelper, R. L., and Hart, M. N. (1989). Purification of murine endothelial cell cultures by flow cytometry using fluorescein-labeled griffonia simplicifolia agglutinin. Am. J. Pathol. 134, 1227-1232.
32. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). "Molecular Clonilg: A Laboratory Manual" 2nd ed., pp. 9.16-9.23, Cold Spring Harbor Laboratory, Cold Spring Harbor.
33. Sapatino, B. V., Petrescu, A. D., Rosenbaum, B. A., Smith, R. r., Piedrahita, J. A., and Welsh, C. J. (1995). Characteristics of cloned cerebrovascular endothelial cells following infection with Theiler's virus. II. Persistent infection. J. Neuroimmunol. 62, 127-135.
34. Savage, C. O., Hughes, C. C., McIntyre, B. W., Picard, J. K., and Pober, J. S. (1993). Human CD4+ T cells proliferate to HLA-DR+ allogencic vascular endothelium. Identification of accessory interactions. Transplantation 56, 128-134.
35. Seino, K., Azuma, M., Bashuda, H., Fukao, K., Yagita, T., and Okumura, K. (1995). Cd86 (B70/B7-2) On Endothelial Cells Co-Stimulates Allogeneic Cd4(+) T Cells. Int. Immunol. 7, 1331-1337.
36. Steimle, V., Siegrist, C. A., Mottet, A., Lisowska-Grospierre, B., and Mach, B. (1994). Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA. Science 265, 106-109.
37. van der Wal, A. C., Das, P. K., Tigges, A. J., and Becker, A. E. (1992). Adhesion molecules on the endothelium and mononuclear cells in human atherosclerotic lesions. Am. J. Pathol. 141, 1427-1433.
38. Wang, Y., Calder, V. L., Lightman, S. L., and Greenwood, J. (1995). Antigen presentation by rat brain and retinal endothelial cells. J. Neuroimmunol. 61, 231-239.
39. Wassom, D. L., Krco, C. J., and David, C. S. (1987). I-E expression and susceptibility to parasite infection. Immunol. Today 8, 39-43.
40. Watson, E. D., and Dixon, C. E. (1993). An immunohistological study of MHC class II expression and T lymphocytes in the endometrium of the mare. Equine Vet. J. 25, 120-124.
41. Welsh, J., Sapatino, B., Rosenbaum, B., Smith, R., and Linthicum, S. (1993). Correlation between susceptibility to demyelination and interferon-gamma induction of major histocompatibility complex class II antigens on murine cerebrovascular endothelial cells.Journal of Neuroimmunology. 48, 91-97.