Potentiation of pulmonary arteriolar vasoconstriction to endothelin-1 by inhibition of nitric oxide synthesis in the intact lung

Microcirculation

Volumn 5, Issue 4, 1998, Pages 289-298

  Roberts, Andrew M ^a   Slaaf, Dick W ^b   Joshua, Irving G ^a  

^a University of Louisville School of Medicine   (United States)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Intravital microscopy; Pulmonary microcirculation; Vasoactive peptide

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; ENZYME INHIBITOR; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NOS3 PROTEIN, RAT;

ANIMAL; ARTERIOLE; ARTICLE; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; LUNG ALVEOLUS; MALE; MICROCIRCULATION; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE; VASCULARIZATION; VASOCONSTRICTION;

ANIMALS; ARTERIOLES; ENDOTHELIN-1; ENZYME INHIBITORS; MALE; MICROCIRCULATION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; VASOCONSTRICTION;

EID: 0032247970     PISSN: 10739688     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1549-8719.1998.tb00078.x     Document Type: Article

References (37)

1. Barnard JW. Barman SA, Adkins WK, Longenecker GL, Taylor AE. (1991). Sustained effects of endothelin-1 on rabbit, dog. and rat pulmonary circulations. Am J Physiol 261 (Heart Circ Physiol 30):H479-H486.
2. Cardell LO, Uddman R, Edvinsson L. (1990). Analysis of endothelin-1-induced contractions of guineapig trachea, pulmonary veins, and different types of pulmonary arteries. Acta Pliysiol Scand 139:103-111.
3. Cassin S, Kristova V, Davis T, Kadowitz P, Cause G. (1991). Tone-dependent responses to endothelin in the isolated perfused fetal sheep pulmonary circulation in situ. J Appl Pliysiol 70:1228-1234.
4. Chatfield BA, McMurtry IF, Hall SL, Abman SH. (1991). Hemodynamic effects of endothelin-1 on ovine fetal pulmonary circulation. Am J Physiol 261 (Regulatory Integrative Comp Physiol 30):R182-R187.
5. Cheng DY, DeWitt BJ, McMahon TJ, Kadowitz PJ. (1994). Comparative effects of L-NNA and alkyl esters of L-NNA on pulmonary vasodilator responses to ACh, BK, and SP. Ani J Physiol 266 (Heart Circ Physiol) 35:H2416-H2422.
6. Cody RJ, Haas GJ, Binkley PF, Capers Q, Kelley R. (1992). Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure. Circulation 85:504-509.
7. Crawley D, Evans TW, Barnes PJ. (1989). EndotheIin-1 constricts human pulmonary resistance vessels in vitro. Br J Pharmacol 99 Suppl:839P.
8. Deleuze PH, Adnot S, Shiiya N, Thoraval FR, Eddahibi S, Braquet P, Chabrier PE, Loisance DV. (1992). Endothelin dilates bovine pulmonary circulation and reverses hypoxic pulmonary vasoconstriction. J Cardiavasc Pharmacol 19:354-360.
9. De Nucci G, Thomas R, D'Orleans-Juste P, Antunes E, Walder C, Warner TD, Vane JR. (1988). Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor. Proc Natl Acad Sci USA 85:9797-9800.
10. Dihn-Xuau AT, Higenbottam TW, Clelland CA, Pepke-Zaba J, Cremona G, Butt AY, Large SR, Wells FC. Wallwork J. (1991). Impairment of endotheliumdependent pulmonary-artery relaxation in chronic obstructive lung disease. N Engl J Med 324:1539-1547.
11. Hasunuma K, Rodman DM, O'Brien RF, McMurtry IF. (1990). Endothelin-1 causes pulmonary vasodilation in rats. Am J Physiol 259 (Heart Circ Physiol 28):H48-H54.
12. Hirata Y, Emori T, Eguchi S, Kanno K, Imai T, Ohta K, Marumo F. (1993). Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. J Clin Invest 91:1367-1373.
13. Huffman A, Grossman E, Oilman KP, Marks E, Keiser HR. (1990). The initial vasodilation and later vasoconstriction of endothelin-1 are selective to specific vascular bed. Am J Hypertens 3:789-791.
14. Horgan MJ, Pinheiro JMB, Malik AB. (1991). Mechanism of endothelin-1-induced pulmonary vasoconstriction. Circ Res 69:157-164.
15. Joshua IG. (1990). Endothelin-induced vasoconstriction of small resistance vessels in the microcirculation of the rat cremaster muscle. Microvasc Res 40:191-198.
16. Kleinman LI, Radford EP Jr. (1964). Ventilation standards for small mammals. J Appl Physiol 19(2):360-362.
17. Langleben D, Demarchie M, Laporta D, Spanier AH, Schlesinger RD, Stewart DJ. (1993). Endothelin-1 in acute lung injury and the adult respiratory distress syndrome. Am Reu Respir Dis 148:1646-1650.
18. Lerman A, Sandok EK, Hildebrand FL Jr, Burnett JC Jr. (1992). Inhibition of endothelium-derived relaxing factor enhances endothelin-mediated vasoconstriction. Circulation 85(5):1894-1898.
19. Lippton HL, Hauth TA, Summer WR, Hyman AL. (1989). Endothelin produces pulmonary vasoconstriction and systemic vasodilation. J Appl Physiol 66:1008-1012.
20. Lippton HL, Cohen GA, McMurtry IF, Hyman AL. (1991). Pnlmonary vasodilation to endothelin isopeptides in vivo is mediated by potassium channel activation. J Appl Physiol 70:947-952.
21. Liu S, Crawley DE, Barnes PJ, Evans TW. (1991). Endothelium-derived relaxing factor inhibits hypoxic pulmonary vasoconstriction in rats. Am Rev Respir Dis 143:32-37.
22. Lüscher TF, Yang Z, Tschudi M, von Segesser L, Stulz P, Boulanger C, Siebenmann R, Turina M, Bühler FR. (1990). Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veins. Circ Res 66:1088-1094.
23. Magazine HI, Malik AB, Bruner CA, Andersen TT. (1992). Acetylated endothelin-1 is a constrictor in guinea pig lung vasculature but not in isolated vascular strips. J Pliarmacol Exp Ther 260:632-636.
24. Mann J, Farrukh IS, Michael JR. (1991). Mechanisms by which endothelin-1 induces pulmonary vasoconstriction in the rabbit. J Appl Physiol 71:410-416.
25. Alasaki T, Kimura S, Yanagisawa M, Goto K. (1991). Molecular and cellular mechanism of endothclin regulation. Circulation 84 (4): 1457-1468.
26. Meyrick B, Reid L. (1979). Ultrastructural features of the distended pulmonary arteries of the normal rat. Anal Rec 193:71-98.
27. Minkes RK, Bellan JA, Saroyan RM, Kerstein MD, Coy DH, Murphy WA, Nossaman BD, McNamara DB, Kadowitz PJ. (1990). Analysis of cardiovascular and pulmonary responses to endothelin-1 and endothelin-3 in the anesthetized cat. J Pharmacol Exp Ther 253:1118-1125.
28. Pohl U, Busse R. (1989). Differential vascular sensitivity. to luminally and adventitially applied endothelin-1. J Cardiovasc Pharmacol 13(Suppl 5):S188-S190.
29. 2 in ferret lungs. Respir Physiol 88:129-140.
30. Raffestin B, Adnot S, Eddahibi S, Macquin-Mavier I, Braquet P, Chabrier PE. (1991). Pulmonary vascular response to endothelin in rats. J Appl Physiol 70:567-574.
31. Rodinan DM, McMurtry IF, Peach JL, O'Brien RF. (1989). Comparative phannacology of rat and porcine endothelin in rat aorta and pulmonary artery. Eur J Pharmacol 165:297-300.
32. Slaaf DW, Tangelder GJ, Reneman RS, Jäger K, Bollinger A. (1987). A versatile incident illuminator for intravital microscopy. Int J Microcirc: Clin Exp 6:391-397.
33. Stamler JS, Loh E, Roddy MA, Currie KE, Creager MA. (1994). Nitric oxide regulates basal systemic and pulmonary vascular resistance in healthy humans. Circulation 89:2035-2040.
34. Stewart DJ, Levy RD, Cernacek P, Langleben D. (1991). Increased plasma endothelin-1 in pulmonary hypertension: marker or mediator of disease? Ann Intern Med 114:464-469.
35. Toga H, Raj JU, Hillyard R, Ku B, Anderson J. (1991). Endothelin effects in isolated, perfused lamb lungs: role of cyclooxygenase inhibition and vasomotor tone. Am J Physiol 261 (Heart Circ Physiol 30):H443-H450.
36. Wong J, Vanderford PA, Fineman JR, Chang R, Soifer SJ. (1993). Endothelin-1 produces pulmonary vasodilation in the intact newborn lamb. Am J Physiol 265 (Heart Circ Physiol 34):H1318-H1325.
37. Yanagisawa M, Kurihara H, Kimura S, Tomobe Y, Kobayashi M, Mitsui Y, Yazaki Y, Goto K, Masaki T. (1988). A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 332:411-415.