Dissection of multi-protein complexes using mass spectrometry: Subunit interactions in transthyretin and retinol-binding protein complexes

Proteins: Structure, Function and Genetics

Volumn 33, Issue SUPPL. 2, 1998, Pages 3-11

  Rostom, Adam A ^a   Sunde, Margaret ^a   Richardson, Samantha J ^c   Schreiber, Gerhard ^c   Jarvis, Stuart ^b   Bateman, Robert ^b   Dobson, Christopher M ^a   Robinson, Carol V ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MICROMASS UK LTD   (United Kingdom)

^c NONE

Author keywords

Mass spectrometry; Nanoflow electrospray; Retinol binding protein; Time of flight; Transthyretin

Indexed keywords

PREALBUMIN; RETINOL BINDING PROTEIN;

ANALYTIC METHOD; ARTICLE; CHICKEN; COMPLEX FORMATION; CRYSTALLOGRAPHY; HUMAN; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ASSEMBLY; SERUM; STOICHIOMETRY; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; INSTRUMENTATION; METABOLISM; METHODOLOGY; PEPTIDE MAPPING; PROTEIN CONFORMATION;

ANIMALS; CHICKENS; HUMANS; MODELS, MOLECULAR; PEPTIDE MAPPING; PREALBUMIN; PROTEIN CONFORMATION; RETINOL-BINDING PROTEINS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 0032247077     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(1998)33:2+<3::AID-PROT2>3.0.CO;2-H     Document Type: Article

References (38)

1. Kanai, M., Raz, A., Goodman, D.W.S. Retinol binding protein; The transport protein for vitamin A in the human plasma. J. Clin. Invest. 47:2025-2044, 1968.
2. Peterson, P. Isolation and properties of a human retinol-transporting protein. J. Biol. Chem. 246:25-33, 1971.
3. Raz, A., Shiratory, T., Goodman, D. Studies on the protein-protein and protein-ligand interactions in retinol transport in plasma. J. Biol. Chem. 245:1903-1912, 1970.
4. Mokady, S., Tal, M. Isolation and partial characterization of retinol binding protein from chicken plasma. Biochim. Biophys. Acta 336:361-366, 1974.
5. Kopelman, M., Cogan, U., Mokady, S., Shinitzky, M. The interactions between retinol-binding proteins and prealbumins studied by fluorescence polarization. Biochim. Biophys. Acta 439:449-460, 1976.
6. Raz, A., Goodman, D.S. The interaction of thyroxine with human plasma prealbumin and with the prealbumin-retinol-binding protein complex. J. Biol. Chem. 244:3230-3237, 1969.
7. Jaarsveld, P.V., Endlehoch, H., Goodman, D.S., Robbins, J. The interaction of human plasma retinol binding protein with prealbumin. J. Biol. Chem 248:4698-4705, 1973.
8. Heller, J., Horwitz, J. The binding stoichiometry of human plasma retinol-binding protein to prealbumin. J. Biol. Chem. 249:5933-5938, 1974.
9. Duan, W., Richardson, S.J., Kohrle, J, et al. Evolution of transthyretin in marsupials. Eur. J. Biochem. 227:396-406, 1995.
10. Schreiber, G., Richardson, S. The evolution of gene expression - Structure and function of transthyretin. Comp. Biochem. Physiol. 116B:137-160, 1997.
11. Blake, C.C.F., Geisow, M., Oatley, S., Rerat, B., Rerat, C. Structure of Prealbumin: Secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 Å J. Mol. Biol. 121:339-356, 1978.
12. Zannnotti, G., Ottonello, S., Berni, R., Monaco, H. Crystal structure of the trigonal form of human plasma retinol binding protein at 2.5 Å resolution. J. Mol. Biol. 230:613-624, 1993.
13. Berni, R., Stoppini, M., Zapponi, M.C., et al. The bovine plasma retinol-binding protein. Eur. J. Biochem. 192: 507-513, 1990.
14. Monaco, H., Rizzi, M., Coda, A. Structure of the complex of two plasma proteins: Transthyretin and retinol binding protein. Science 268:1039-1041, 1995.
15. Przybylski, M., Glocker, M. Electrospray mass spectrometry of biomacromolecular complexes with noncovalent interactions - New analytical perspectives for supramolecular chemistry and molecular recognition processes. Angew. Chem. Int. Ed. Engl. 35:806-826, 1996.
16. Wilm, M. & Mann, M. Electrospray and Taylor - Cone theory, Dole's beam of macromolecules at last? Int. J. Mass Spectrom. Ion Proc. 136:167-180, 1994.
17. Fitzgerald, M., Chernushevich, I., Standing, K., Whitman, C., Kent, S. Probing the oligomeric structure of an enzyme by electrospray ionization time-of-flight mass spectrometry. Proc. Natl. Acad. Sci. USA 93:6851-6856, 1996.
18. Karas, M., Hillenkamp, F. Laser desorption ionization of protein with molecular masses exceeding 10,000 daltons. Anal.Chem. 60:2299-2301, 1988.
19. Dawson, J., Guilhaus, M. Orthogonal-acceleration time-of-flight mass spectrometer. Rapid Commun. Mass Spectrom. 3:155-159, 1989.
20. Verentchikov, A., Ens, W., Standing, K. A reflecting time of flight mass spectrometer with an electrospray ion source and orthogonal extraction. Anal. Chem. 66:126-133, 1994.
21. Loo, J.A. Observation of large subunit protein complexes by electrospray ionization mass spectrometry. J. Mass Spectrom. 30:180-183, 1995.
22. Nettleton, E., Sunde, M., Lai, Z. H., et al. Protein subunit interactions and structural integrity of amyloidogenic transthyretins - Evidence from electrospray mass spectrometry. J. Mol Biol., 281, 553-564, 1998.
23. Sunde M. et al. The crystal structure of transthyretin from chicken. Eur. J. Biochem. 236, 491-499 (1996).
24. Gerstein, M., Chothia, C. Packing at the protein-water interface. Proc. Natl. Acad. Sci. USA 93:10167-10172, 1996.
25. Lai, Z., Lashuel, H.A., Kelly, J.W. Characterization of the transthyretin acid denaturation pathway by analytical ultracentrifugation: Implications for amyloid fibril formation. Biochemistry, in press.
26. Fex, G., Albertsson, P., Hansson, B. Interaction between prealbumin and retinol-binding protein studied by affinity chromatography, gel filtration and two phase partition. Eur. J. Biochem. 99:353-360, 1979.
27. Chowdhury, S., Katta, V., Chait, B. Probing conformational changes in proteins by mass spectrometry. J. Am. Chem. Soc. 112:9012-9013, 1990.
28. Chowdhury, S., Chait, B. Analysis of mixtures of closely related forms of bovine trypsin by electrospray inioziation mass spectrometry - Use of charge state distribution to resolve ions of the different forms. Biochem. Biophys. Res. Commun. 173:927-931, 1990.
29. Mirza, U., Chait, B. Effects of anions on the positive ion electrospray ionization mass spectra of peptides and proteins. Anal. Chem. 66:2898-2904, 1994.
30. Kebarle, P., Tang, L. From ions in solution to ions in the gas phase. Anal. Chem. 65:972-986, 1993.
31. Cowan, S., Newcomer, M., Jones, T. Cristallographic refinement of human serum retinol binding protein at 2 Å resolution. Proteins 8:44-61, 1990.
32. Vieira, A., Kuchler, K., Schneider, W. Retinol in avian oogenesis - Molecular properties of the carrier protein. DNA Cell Biol. 14:403-410, 1995.
33. Coates, G., Monaco, H., Blake, C., Sunde, M. A model of the retinol-binding protein - transthyretin protein:protein complex in chicken. Submitted for publication.
34. Guan, Z., Drader, J., Campbell, V. & Laude, D. Real-time monitoring of gas-phase reactions of a single ion population using the remeasurement experiment in Fourier transform ion-cyclotron resonance mass spectrometry. Anal. Chem. 67:1453-1458, 1995.
35. Kraulis, P. Molscript: A program to produce both detailed and schematic plots of protein structures. J. Appl. Crystallogr. 24:946-950, 1991.
36. Esnouf, R.M. An extensively modified version of MolScript that includes greatly enhanced coloring capabilities. J. Mol. Graph. Modeling 15:132-136, 1997.
37. Merritt, E., Murphy, M. Raster 3D version 2.0: A program for photorealistic molecular graphics. Acta Crysallogr. D 50:869-873, 1994.
38. Chung, E.W., Nettleton, E.J., Morgan, C.J., et al. Hydrogen exchange properties of proteins in native and denatured states monitored by mass spectrometry and NMR. Protein Sci. 6:1316-1324, 1997.