Ca2+ depolarizes adrenal cortical cells through selective inhibition of an ATP-activated K+ current

American Journal of Physiology - Cell Physiology

Volumn 275, Issue 6 44-6, 1998, Pages

  Gomora, Juan Carlos ^a   Enyeart, John J ^a,b  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Adrenal cortex; Angiotensin II; Cortisol secretion; Membrane depolarization; Potassium channel

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANGIOTENSIN; CALCIUM ION; CALMODULIN; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; IONOMYCIN; POTASSIUM; POTASSIUM ION; PROTEIN KINASE; ADENYLYLIMIDODIPHOSPHATE; ANGIOTENSIN II; CALCIUM; IONOPHORE; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT;

ADRENAL CORTEX; AMPLITUDE MODULATION; ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CATTLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; MEMBRANE DEPOLARIZATION; NONHUMAN; PATCH CLAMP; POTASSIUM TRANSPORT; PRIORITY JOURNAL; ANIMAL; CELL CULTURE; CELL MEMBRANE POTENTIAL; CYTOLOGY; DRUG EFFECT; METABOLISM; OSMOLARITY; PHYSIOLOGY; ZONA FASCICULATA;

ANIMALIA; BOS TAURUS; BOVINAE;

ADENOSINE TRIPHOSPHATE; ADENYLYL IMIDODIPHOSPHATE; ADRENAL CORTEX; ANGIOTENSIN II; ANIMALS; CALCIUM; CALMODULIN; CATTLE; CELLS, CULTURED; IONOMYCIN; IONOPHORES; MEMBRANE POTENTIALS; OSMOLAR CONCENTRATION; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS; ZONA FASCICULATA;

EID: 0032246497     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1998.275.6.c1526     Document Type: Article

References (18)

1. Bregestovski, P., A. Redkozubov, and A. Alexeev. Elevation of intracellular calcium reduces voltage-dependent potassium conductance in human T cells. Nature 319: 776-778, 1986.
2. Brooks, S. P. J., and K. B. Storey. Bound and determined: a computer program for making buffers of denned ion concentrations. Anal. Biochem. 201: 119-126, 1992.
3. 2+ and aldosterone production in bovine adrenal glomerulosa cells. J. Biol. Chem. 259: 8863-8869, 1984.
4. 2+-calmodulin of cyclic nucleotide-activated channel of rat olfactory receptor neurons. Nature 368: 545-548, 1994.
5. 2+ regulation of mslo large conductance Ca-activated channels. J. Gen. Physiol. 109: 647-673, 1997.
6. + current in adrenal cortical cells through nonhydrolytic binding. J. Gen. Physiol. 110: 679-692, 1997.
7. 2+ are required for ACTH-stimulated cortisol synthesis by bovine adrenal zona fasciculata cells. Mol. Endocrinol. 7: 1031-1040, 1993.
8. + current in adrenocortical cells by an A-kinase-independent mechanism requiring ATP hydrolysis. J. Gen. Physiol. 108: 251-264, 1996.
9. Gospodarowicz, D., C. R. Ill, P. J. Hornsby, and G. N. Gill. Control of bovine adrenal cortical cell proliferation by fibroblast growth factor. Lack of effect of epidermal growth factor. Endocrinology 100: 1080-1089, 1977.
10. Hamill, O. P., A. Marty, E. Neher, B. Sakmann, and F. J. Sigworth. Improved patch clamp techniques for high resolution current recording from cells and cell-free membrane patches. Pflügers Arch. 391: 85-100, 1981.
11. Hilgemann, D. W. Cytoplasmic ATP-dependent regulation of ion transporters and channels: mechanisms and messengers. Annu. Rev. Physiol. 59: 193-220, 1997.
12. Hille, B. Ionic Channels of Excitable Membranes. Sunderland, MA: Sinauer, 1992.
13. Kaupp, U. B. The cyclic nucleotide-gated channels of vertebrate photoreceptors and olfactory epithelium. Trends Neurosci. 14: 150-156, 1991.
14. 2+ concentration. Neuron 6: 1009-1014, 1991.
15. + channel protein on calmodulin affinity columns after detergent solubilization of luminal membranes from outer renal medulla. FEBS Lett. 216: 211-216, 1987.
16. Levitan, I. B. Modulation of ion channels by protein phosphorylation and dephosphorylation. Annu. Rev. Physiol. 56: 193-212, 1994.
17. Liu, M., T. Chen, B. Ahamed, J. Li, and K.-W. Yau. Calcium-calmodulin modulation of the olfactory cyclic nucleotide gated cation channel. Science 266: 1348-1354, 1994.
18. Marrion, N. V. Calcineurin regulates M channel modal gating in sympathetic neurons. Neuron 16: 163-173, 1996.