Estrogen replacement modulates resistance artery smooth muscle and endothelial α2-adrenoceptor reactivity

Endothelium: Journal of Endothelial Cell Research

Volumn 6, Issue 2, 1998, Pages 133-141

  Ferrer, Mercedes ^a   Osol, George ^a  

^a UNIVERSITY OF VERMONT   (United States)

Author keywords

Clonidine; Endothelium; Estrogen; Pressurized mesenteric arteries; Vascular smooth muscle; 2 adrenoceptor

Indexed keywords

ANIMALIA;

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ESTROGEN; NITRIC ACID; PROSTAGLANDIN; YOHIMBINE;

ANIMAL; ARTERY; ARTICLE; DRUG EFFECT; FEMALE; METABOLISM; RAT; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

ADRENERGIC ALPHA-ANTAGONISTS; ANIMALS; ARTERIES; ENDOTHELIUM, VASCULAR; ESTROGENS; FEMALE; MUSCLE, SMOOTH, VASCULAR; NITRIC ACID; PROSTAGLANDINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-2; YOHIMBINE;

EID: 0032242217     PISSN: 10623329     EISSN: None     Source Type: Journal    
DOI: 10.3109/10623329809072200     Document Type: Article

References (39)

1. Altura BM: Sex andestrogens and responsiveness of terminal arterioles to neurohypophyseal hormones and catecholamines. J Pharmacol Exp Ther 1975; 193:403-412.
2. Bell DR, Rensberger HJ, Koritnik DR, Koshy A: Estrogen pretreatment directly potentiates endothelium-dependent vasorelaxation of porcine coronary arteries. Am J Physiol 1995, 268: H377-H383.
3. Bush TL, Barret-Connor E, Cowan LD, Criqui MH, Wallace RB, Suchindran CM, Tyroler HA, Rifkind BM: Cardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Programs Follow-up Study. Clin Invest 1987; 6: 1102-1109.
4. Bylund DB, Ray-Prenger C, Murphy TJ: Alpha-2A and alpha-2B adrenergic receptor subtypes: antagonist binding in tissues and cell lines containing only one subtype. J Pharmacol Exp Ther 1988; 245 : 600-607.
5. Clarkson TB, Anthony MS, Klein KP: Effects of estrogen treatment on arterial wall structure and function. Drugs. 1994; 47: S42-S51.
6. Colucci WS, Gimbrone MA, McLaughlin MK, Halpern W, Alexander RW: Increased vascular catecholamine sensitivity and α-adrenergic receptor affinity in female and estrogen-treated male rats. Cir Res 1982; 50: 805-811.
7. Conrad KP, Mosher MD, Brinck-Johnsen T, Colpoys MC: Effects of 17β-estradiol and progesterone on pressor responses in conscious ovariectomized rats. Am J Physiol 1994; 266: R1267-R1272.
8. Cordellini S, Carvalho MHC, Scivolelto R, Fortes ZB, Nigro D: Indirect evidence for an endothelium-derived contracting factor release in aorta of deoxycorticosterone acetate-salt hypertensive rats. J Hypertens 1990; 8: 53-60.
9. 2-adrenoceptors: evidence for and against a further subdivision. Pharmacol Ther 1989; 44: 241-284.
10. Egleme C, Godfraind T, Miller RC: Enhanced responsiveness of rat isolated aorta to clonidine after removal of the endothelial cells. Br J Pharmacol 1984; 81: 16-18.
11. Ferrer M, Meyer M, Osol G: Estrogen replacement increases b-adrenoceptor-mediated relaxation of rat mesenteric arteries. J Vasc Res 1996; 33: 124-131.
12. Fortes ZB, Nigro D, Scivoletto R, Carvalho MHC: Indirect evidence for an endothelium-derived contracting factor released in arterioles of deoxycorticosterone acetate salt hypertensive rats. J Hypertens 1990; 8: 1043-1048.
13. Gilligan DM, Quyyumi AA, Cannon RO: Effect of physiological levels of estrogen on coronary vasomotor function in postmenopausal women. Circulation 1994; 89: 2545-2551.
14. Giudicelli Y, Dieudonne MN, Lacasa D, Pasquier YN, Pecquery R: Modulation by sex hormones of the membranous transducing system regulating fatty acid mobilization in adipose tissue. Prostaglandins Leukot Essent Fatty Acids 1993; 48: 91-100.
15. Goetz RM, Morano I, Calvoni T, Studer R, Holtz J: Increased expression of endothelial constitutive nitric oxide synthase in rat aorta during pregnancy. Biochem. Biophys. Res. Comm. 1994; 205: 905-910.
16. Halpern W, Osol G, Coy GS: Mechanical behavior of pressurized in vitro prearteriolar vessels determined with a video system. Ann Biomed Eng 1984; 12: 463-179.
17. Karkanias GB, Etgen AM: Estradiol attenuates alpha 2-adrenoceptor mediated inhibition of hypothalamic norepinephrine release. J Neurosci 1993; 13: 3448-55.
18. Kauser K, Rubanyi GM: Gender difference in endothelial dysfunction in the aorta of spontaneously hypertensive rats. Hypertension 1995; 25: 517-523
19. Knopp RH: The effects of postmenopausal estrogen therapy on the incidence of arteriosclerotic vascular disease. Obstet Gynecol 1988; 72: 23S-30S.
20. Larsson B, Andersson KE, Batra S, Mattiasson A, Sjogren C: Effects of estradiol on norepinephrine-induced contractions, alpha adrenoceptor number and norepinephrine content in the female rabbit urethra. J Pharmacol Exp Ther 1984; 229: 557-563.
21. Li Z., Duckles SP: Influence of gender on vascular reactivity in the rat. J Pharmacol Exp Ther 1994; 268: 1426-1431.
22. Luscher TM, Vanhoutte PM: Endothelium-dependent contractions to acetylcholine in the aorta of the spontaneously hypertensive rat. Hypertension 1986; 8: 344-348.
23. Magness RR, Rosenfeld CR: Local and systemic estradiol-17β: effects on uterine and systemic vasodilation. Am J Physiol 1989; 256: E536-E542.
24. Meyer M, Cummings K, Osol, G: Estrogen replacement attenuates resistance artery adrenergic sensitivity via endothelial vasodilators. Am J Physiol 1997; 272: H2264-H2270.
25. Miller VM, Gisclard V, Vanhoutte PM: Modulation of endothelium dependent and vascular smooth muscle responses by oestrogens. Phlebology 1988; 224: 19-22.
26. Miller VM, Vanhoutte PM: Endothelium-dependent contractions to arachidonic acid are mediated by products of cyclooxygenase. Am J Physiol 1985; 248: H432-H437.
27. Mishra N, Hamilton CA, Jones CR, Reid JL: The effects of sexual maturation on a-adrenoceptors in female rabbits. Eur J Pharmacol 1985; 112: 243-248.
28. Nigro D, Fortes ZB, Scicovetto R, Carvalho MH: Simultaneous release of endothelium-derived relaxing and contracting factors induced by noradrenaline in normotensive rats. Gen Pharmacol 1990; 21: 443-446.
29. Osol G, Cipolla M, Knutson S: A new method for mechanically denuding the endothelium of small (50-150 μm) arteries with an human hair. Blood Vessels 1989; 26: 320-324.
30. Osol G, Halpern W: Myogenic properties of cerebral blood vessels from normotensive and hypertensive rats. Am J Physiol 1985; 249:H914-H921.
31. Richelsen B: Increased α2- but similar β-adrenergic receptor activities in subcutaneous gluteal adipocytes from females compared with males. Eur J Clin Invest 1986; 16: 302-309.
32. Stevenson JC, Crook D, Godsland IF, Collins P, Whitehead MI: Hormone replacement therapy and the cardiovascular system. Drugs 1994; 47: S35-S41.
33. Thchidu M, Richard V, Buhler FR, Lüscher TF: Importance of endothelium-derived nitric oxide in porcine coronary resistance arteries. Am J Physiol 1991; 260: H13-H20.
34. Vargas R, Delaney M, Farhat MY, Wolfe R, Rego A, Ranwell PW: Effect of estrdiol 17§ on pressor responses of rat mesenteric bed to norepinephrine, K±, and U-46619. J Cardiovasc Pharmacol 1995; 25: 200-206.
35. Vass-Lopez A, Garcia-Villar R, Iafontan M, Toufain PL: Influence of steroid hormone treatments or pregnancy on [3H]prazosin and [3H]rauwolscine binding to myometrial a-adrenoceptors in the ewe. J Endocrinol 1990; 127: 471-479.
36. 2-adrenoceptor agonist-induced contraction in rat mesenteric artery upon removal of endothelium. Eur J Pharmacol 1986; 122: 349-352.
37. Wiener CP, Lizasoain I, Baylis SA, Knowles RG, Charles IG: Induction of calcium-dependent nitric oxide synthases by sex hormones. Proc. Natl. Acad. Sci. USA 1994; 91: 5212-5216.
38. Williams JK, Adams MR, Klopfenstein HS: Estrogen modulate responses of atherosclerotic coronary arteries. Circulation 1990; 81: 1680-1687.
39. Zhang A, Altura BT, Altura BM: Sexual dimorphism of vascular smooth muscle responsiveness is dependent on anions and estrogen. Steroids 1991; 56: 524-526.