Increased Serum Concentrations of Carbohydrate-Deficient Transferrin (CDT) in Patients with Cystic Fibrosis

Upsala Journal of Medical Sciences

Volumn 103, Issue 3, 1998, Pages 231-236

  Larsson, Anders ^a   Flodin, Mats ^a   Kollberg, Hans ^b  

^a UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY CHILDREN S HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE DEFICIENT TRANSFERRIN; CARBOHYDRATE-DEFICIENT TRANSFERRIN; DRUG DERIVATIVE; ISOENZYME; TRANSFERRIN;

ADOLESCENT; ADULT; ARTICLE; BLOOD; CHILD; CYSTIC FIBROSIS; ENZYMOLOGY; FEMALE; HUMAN; IMMUNOASSAY; ION EXCHANGE CHROMATOGRAPHY; MALE;

ADOLESCENT; ADULT; CHILD; CHROMATOGRAPHY, ION EXCHANGE; CYSTIC FIBROSIS; FEMALE; HUMANS; IMMUNOASSAY; ISOENZYMES; MALE; TRANSFERRIN;

EID: 0032241955     PISSN: 03009734     EISSN: None     Source Type: Journal    
DOI: 10.3109/03009739809178952     Document Type: Article

References (17)

1. Barasch, J., Kiss, B., Prince, A., Saiman, L., Gruenert, D & al-Awqati, Q.: Defective acidification of intracellular organelles in cystic fibrosis. Nature 352: 70-73, 1991.
2. Cheng, P.W., Boat, T.F., Cranfill, K., Yankaskas, J.R. & Boucher, R.C., Increased sulfation of glycoconjugates by cultured nasal epithelial cells from patients with cystic fibrosis. J Clin Invest 84: 68-72, 1989.
3. Chosh, P. & Lakshman, M.R.: Chronic ethanol induced impairment of hepatic glycosylation machinery in rat is independent of dietary carbohydrate. Alcoholism Clin Exp Res 21: 76-81, 1997.
4. Dosanjh, A., Lencer, W., Brown, D., Ausiello, D.A. & Stow, J.L.: Heterologous expression of delta F508 CFTR results in decreased sialylation of membrane glycoconjugates. Am J Physiol 266: C360-366, 1994.
5. Duthel, S & Revol, A.: Glycan microheterogeneity of alpha 1-antitrypsin in serum and meconium from normal and cystic fibrosis patients by crossed immunoaffinoelectrophoresis with different lectins (Con A, LCA, WGA). Clin Chim Acta 215: 173-187, 1993
6. Goldberg, D.M & Kapur, B.M.: Enzymes and circulating proteins as markers of alcohol abuse. Clin Chim Acta 226: 191-209, 1994.
7. Jeppsson, J.O., Kristensson, H. & Fimiani, C., Carbohydrate-deficient transferrin quantified by HPLC to determine heavy consumption of alcohol Clin Chem 39: 2115-2120, 1993
8. Mårtensson, O., Harlin, A., Brandt, R., Seppa, K. & Sillanaukee, P.: Transferrin isoform distribution, gender and alcohol consumption. Alcohol Clin Exp Res 2: 1710-1715, 1997.
9. Rosenstein, B J & Zeitlin, P.L., Cystic fibrosis. Lancet 351: 277-282, 1998.
10. Schellenberg, F., Martin, M., Caces, E., Benard, J.Y. & Weill, J.: Nephelometric determination of carbohydrate deficient transferrin Clin Chem 42: 551-557, 1996
11. Stibler, H.: Carbohydrate-deficient transferrin in serum, a new marker of potentially harmful alcohol consumption reviewed. Clin Chem 37: 2029-203, 1991.
12. Stibler, H., Borg, S. & Joustra, M.: A modified method for the assay of carbohydrate-deficient transferrin (CDT) in serum. Alcohol Alcoholism Suppl 1: 451-454, 1991
13. Stibler, H., von Dobeln, U., Kristiansson, B. & Guthenberg, C.: Carbohydrate-deficient transferrin in galactosaemia. Acta Paediatr 86: 1377-1378, 1997
14. Tsui, L C.: The cystic fibrosis transmembrane conductance regulator gene. Am J Respir Crit Care Med 151: S47-53, 1995
15. Warwick, W.J., Cystic fibrosis sweat test for newborns. JAMA 198, 177-180, 1966.
16. Xin, Y., Lasker, J.M., Rosman, A.S. & Lieber, C S.: Isoelectric focusing/western blotting, a novel and practical method for quantitation of carbohydrate-deficient transferrin in alcoholics. Alcohol Clin Exp Res 15: 814-821, 1991.
17. Yersin, B., Nicolet, J F., Dercrey, H., Burnier, M., van Melle, G. & Pecoud, A: Screening for excessive alcohol drinking. Comparative value of carbohydrate-deficient transferrin, gamma-glutamyltransferase, and mean corpuscular volume. Arch Intern Med 155: 1907-1911, 1995.