Evidence for a renin receptor on human mesangial cells: Effects on PAI and GMPC;Mise en evidence d'un recepteur de la renine sur les cellules mesangiales humaines: Effets sur le PAI1 et sur le GMPc

Nephrologie

Volumn 19, Issue 7, 1998, Pages 411-416

  Nguyen, G ^a,b   Bouzhir, L ^a   Delarue, F ^a   Rondeau, E ^a   Sraer, J D ^a  

^a INSERM   (France)

^b HÔPITAL TENON   (France)

Author keywords

CGMP; Human mesangial cells; PAI 1; Renin receptor

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ASPARTIC PROTEINASE; CAPTOPRIL; CELL RECEPTOR; CYCLIC AMP; CYCLIC GMP; FIBRIN; IODINE 125; PLASMINOGEN ACTIVATOR INHIBITOR; RENIN; RENIN INHIBITOR; RO 42 5982; THYMIDINE; TISSUE PLASMINOGEN ACTIVATOR; TRITIUM; UNCLASSIFIED DRUG; CALCIUM; CELL SURFACE RECEPTOR; PLASMINOGEN ACTIVATOR INHIBITOR 1; RADIOACTIVE IODINE; RECOMBINANT PROTEIN;

ARTICLE; CELL CULTURE; CELL IMMORTALIZATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; MESANGIUM CELL; RECEPTOR BINDING; BIOSYNTHESIS; CHEMISTRY; MESANGIUM; METABOLISM; REVIEW; SECRETION;

CALCIUM; CYCLIC GMP; GLOMERULAR MESANGIUM; HUMANS; IODINE RADIOISOTOPES; PLASMINOGEN ACTIVATOR INHIBITOR 1; RECEPTORS, CELL SURFACE; RECOMBINANT PROTEINS; RENIN; TISSUE PLASMINOGEN ACTIVATOR;

EID: 0032238989     PISSN: 02504960     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (8)

1. Chansel D, Dussaule J-C, Ardaillou N, Ardaillou R. Identification and regulation of renin in human cultured mesangial cells. Am J Physiol 1987; 252: F32-F8.
2. Takahashi S, Ohsawa T, Miura R, Miyake Y. Purification and characterization of renin-binding protein (RnBp) from porcine kidney. J Biochem (Tokyo) 1983; 93: 1583-94.
3. Inoue H, Fukui K, Takahashi S, Miyake Y. Genetic and molecular properties of human and rat renin-binding poteins with reference to the function of the leucine-zipper motif. J Biochem (Tokyo) 1991; 100:493-500.
4. Maru I, Ohta Y, Murata K, Tsukada Y. Molecular cloning and identification of N-Acyl-D-glucosamine 2 epimerase from porcine kidney as renin-binding protein. J Biol Chem 1996; 271: 16294-9.
5. Campbell DJ, Valentijn AJ. Identification of vascular renin-binding proteins by chemical cross-linking : Inhibition of binding of renin by renin inhibitors. J Hypertens 1994; 12: 879-90.
6. Sraer JD, Delarue F. Hagège J, Feunten J, Pinet F, Nguyen G, Rondeau E. Stable cell lines of T-SV 40 immortalized human glomerumar mesangial cells. Kidney Int 1996; 49: 267-70.
7. Nguyen G, Delarue F, Berrou J, Rondeau E, Sraer JD. Specific receptor of renin on human mesangial cells in culture increases plasminogen activator inhibitor-1 antigen. Kidney Int 1996; 50: 1897-903.
8. Fischli W, Clozel JP, El Amrani. K, Wostl W, Neidhart W, Stalder H, Branca Q. RO 42-5892 is a potent orally active renin inhibitor in primates. Hypertension 1991; 8: 22-31.