In vitro modulation of AL-amyloid formation by Human Mesangial Cells exposed to amyloidogenic Light Chains

Amyloid

Volumn 5, Issue 4, 1998, Pages 238-246

  Isaac, Jorge ^a   Kerby, Jeff D ^b   Russell, William J ^a   Dempsey, Susanna C ^a   Sanders, Paul W ^c   Herrera, Guillermo A ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b Kentucky   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

Amyloidogenic light chain; In vitro AL amyloidosis; Mesangial cells

Indexed keywords

AMYLOID; CHLOROQUINE; IMMUNOGLOBULIN LIGHT CHAIN; THROMBOSPONDIN; TRANSFORMING GROWTH FACTOR BETA;

AMYLOIDOSIS; ARTICLE; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; HUMAN; ISOLATION AND PURIFICATION; KIDNEY DISEASE; KIDNEY TUBULE; MESANGIUM; METABOLISM; PATHOLOGY; URINE;

AMYLOID; AMYLOIDOSIS; CELLS, CULTURED; CHLOROQUINE; GLOMERULAR MESANGIUM; HUMANS; IMMUNOGLOBULIN LIGHT CHAINS; KIDNEY DISEASES; KIDNEY TUBULES; THROMBOSPONDINS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0032235059     PISSN: 13506129     EISSN: None     Source Type: Journal    
DOI: 10.3109/13506129809007296     Document Type: Article

References (42)

1. Buxbaum J (1992). Mechanisms of disease: Monoclonal im-munoglobulin deposition. Hematol/Oncol Clin N Am 6:323-346
2. Aterman, K (1976). A historical note on the iodine-sulphuric acid reaction of amyloid. Histochemistry 49:31-143
3. Shirahama T, Benson MD, Cohen AS, and Tanaka A (1973). Fibrillar assemblage of variable segments of immunoglobulin light chains: An electron microscopic study. J Immunol 110:21-30
4. White GC, Jacobson RJ, Binder RA, and Glenner GG (1975). Immunoglobulin D myeloma and amyloidosis: Immunochemical and structural studies of Bence Jones and amyloid fibrillar protein. Blood 46:713-722
5. Glenner GG (1980). Medical Progress. Amyloid deposits and amyloidosis. The β-fibrilloses (part 1 of 2). N Eng J Med 302:1283-1292
6. Kazimiercrak J (1972). Ultrastructural observations on the first amyloid to be found in the spleen of casein treated mice. Acta Pathol Microbiol Scand 80:141-150
7. Sipe J (1992). Amyloidosis. Ann Rev Biochem 61:947-974.
8. Tagouri YM, Sanders PW, Picken MM, Siegal GP, Kerby JD and Herrera GA (1996). In vitro AL-amyloid formation by rat and human mesangial cells. Lab Invest 74:290-302
9. Kisilevsky R, Gruys E and Shirahama T (1995). Does amyloid enhancing factor(AEF) exist? Is AEF a single biological entity. Amyloid. In J Clin Invest 2:128-133
10. Ganowiak K, Hultman P, Engstrom U, Gustavsson A and Westermark P (1994). Fibrils from synthetic amyloid-related peptides enhance development of experimental AA-amyloidosis in mice. Biochem Biophys Res Commun 199:306-312
11. Khiave-Alizadeh K, Normand J, Chronopoulos S, Ali A and Ali-khan Z (1991). Amyloid enhancing factor activity is associated with ubiquitin. Virchows Archiv A Pathol Anat 420:139-148
12. Cotran R, Kumar V and Robbins S (1994). Diseases of immunity. In Schoen F.J. (ed). Robbins Pathologic Basis of Diseases, 5th Ed., pp231-238. (Philadelphia: W.B. Saunders)
13. Solomon A and Weiss DT (1995). Protein and host factors implicated in the pathogenesis of light chain amyloidosis (AL amyloidosis). Amyloid: Int J Exp Clin Invest 2:269-279
14. Stevens FJ, Myatt EA, Chang CH, Westholm FA, Eulitz M, Weiss DT, Murphy C, Solomon A and Schiffer M (1995). A molecular model for self-assembly of amyloid fibrils: Immunoglobulin Light Chains. Biochemistry 34:10697-10702
15. Lawrence DA (1995). Transforming growth factor β: An overview. Kidney Int'l 47:S19-S23
16. Border WA, Noble NA and Ketteler M(1995). TGF-β: A cytokine mediator of glomerulosclerosis and a target for therapeutic intervention. Kidney Int'l 47:S59-S61
17. Herrera GA. Shultz JJ, Soong S-J and Sanders PW (1994). Growth factors in monoclonal light-chain-related renal diseases. Hum Pathol 25:883-892
18. Throckmorton DC, Brogden AP, Min B, Rasmussen H and Kashgarian M (1995). PDGF and TGF-β mediate collagen production by mesangial cells exposed to advanced glycosylation end products. Kidney Int'l 48:111-117
19. Ayo SH, Radnik RA, Garoni JA, Glass WF II and Kreisberg JI (1990). High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells. Am J Pathol 136:1339-1348
20. Zhu L, Herrera GA, Murphy-Ullrich JE, Huang Z-Q and Sanders PW (1995). Pathogenesis of glomerulosclerosis in light chain deposition disease: Role for transforming growth factor-β. Am J Pathol 147:375-385
21. Raugi GJ and Lovett DH (1987). Thrombospondin secretion by cultured human glomerular mesangial cells. Am J Pathol 129:364-372
22. Jaffe EA, Ruggiero JT, Leung LL, Doyle MJ, McKeown-Longo PJ and Mosher EF (1983). Cultured human fibroblasts synthesize and secrete thrombospondin and incorporate it into extracellular matrix. Proc Nat'l Acad Sci USA 80:998-1002
23. Marinides GN, Suchard SJ and Mookerjee BK (1994). Role of thrombospondin in mesangial cell growth: Possible existence of an autocrine feedback growth circuit. Kidney Int'l 46:350-357
24. McGregor B, Colon S, Mutin M, Chignier E, Zech P and McGregor J (1994). Thrombospondin in human glomerulopathies. A marker on inflammation and early fibrosis. Am J Pathol 144:1281-1287
25. Bornstein P (1992). Thrombospondins: structure and regulation of expression. FASEB J 6:3290-3299
26. Mosher DF (1990). Physiology of thrombospondin. Ann Rev Med 41:85-97
27. Lahav J (1993). The functions of thrombospondin and its involvement in physiology and pathophysiology. Biochim Byophys Acta 1182:1-14
28. Dash PK and Moore AN (1993). Inhibitors of endocytosis, endosome fusion and lysosomal processing inhibit proteolysis of the amyloid precursor protein. Neurosci Lett 164:183-186
29. Tietze C, Schlesinger P and Stahl P (1980). Chloroquine and ammonium ion inhibit receptor-mediated endocytosis of mannose-glycoconjugates by macrophages: Apparent inhibition of receptor recycling. Biochem Biophys Res Comm 93:1-8
30. Gonzalez-Noriega A, Grubb JH, Talkad V and Sly WS (1980). Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor cycling. J Cell Biol 85:839-852
31. Poole B and Ohkuma S (1981). Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages. J Cell Biol 90:665-669
32. Cardelli JA, Richardson J and Miears D (1989). Role of acidic intracellular compartments in the biosynthesis of Dictyostelium lysosomal enzymes. J Biol Chem 264:3454-3463
33. 2M receptors in fibroblasts. Cell 20:37-43
34. Epstein WV, Tan M and Wood IS (1974). Formation of "amyloid" fibrils in vitro by action of human kidney lysosomal enzymes on Bence Jones proteins. J Lab Clin Med 84:107-110
35. Solomon A and Haverman K (1978). Bence Jones proteins and light chains of immunoglobulins-XVII. Unique susceptibility of certain kappa chains to proteolysis by human granulocyte-derived neutral proteases. Immunochemistry 15:453-458
36. Sanders PW and Booker BB (1992). Pathobiology of cast nephropathy from human Bence Jones proteins. J Clin Invest 89:630-639
37. Harper PA, Robinson JM, Hoover RL, Wright TC and Karnovsky MJ (1984). Improved methods for culturing rat glomerular cells. Kidney Int'l 26:875-880
38. Schultz-Cherry S and Murphy-Ullrich JE (1993). Thrombospondin causes activation of latent transforming growth factor-β secreted by endothelial cells by a novel mechanism. J Cell Biol 122:923-932
39. Taub, G (1996) Misfolding the way to disease. Science 271:1493-1495
40. Pircher R and Jullien P (1986). β-transforming growth factor is stored in human blood platelets as a latent high molecular weight complex. Biochem Biophys Res Commun 136:30-37
41. Wisniewski T and Frangione B (1992). Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid. Neurosci Lett 135:235-238
42. Gallo G, Wisniewski T, Choi-Miura N-H, Ghiso J and Frangione B (1994). Potential role of apolipoprotein-E in fibrillogenesis. Am J Pathol 145:526-530