Absence of dopaminergic control on melanotrophs leads to Cushing's-like syndrome in mice

Molecular Endocrinology

Volumn 12, Issue 8, 1998, Pages 1133-1139

  Saiardi, A ^a   Borrelli, E ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERMEDIN; BETA ENDORPHIN; CORTICOTROPIN; DOPAMINE; DOPAMINE 2 RECEPTOR;

ADRENAL GLAND; ANIMAL TISSUE; ARTICLE; CORTICOTROPIN BLOOD LEVEL; CUSHING SYNDROME; DOPAMINERGIC SYSTEM; GENE EXPRESSION REGULATION; HYPOPHYSIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 0032230258     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.12.8.0144     Document Type: Article

References (28)

1. Regulation of the pro-opiomelanocortin mRNA levels in rat pituitary by dopaminergic compounds
2. Inhibitory control of prolactin and Pit-1 gene promoters by dopamine. Dual signaling pathways required for D2 receptor-regulated expression of the prolactin gene
3. Dopamine D2 receptors in signal transduction and behavior
4. Differential expression of the mouse D2 dopamine receptor isoforms
5. Dopamine receptors: Molecular biology, biochemistry and behavioural aspects
6. Preferential coupling between dopamine D2 receptors and G proteins
7. Dopamine D2-receptor messenger RNA is differentially regulated by dopaminergic agents in rat anterior and neurointermediate pituitary
8. D-2 dopamine receptor-mediated inhibition of pro-opiomelanocortin synthesis in rat intermediate lobe. Abolition by pertussis toxin or activators of adenylate cyclase
9. Regulation of proopiomelanocortin gene expression in pituitary
10. CRF stimulates alpha-MSH secretion and cyclic AMP accumulation in rat pars intermedia cells
11. Regulation of the messenger ribonucleic acid for corticotropin-releasing factor in the paraventricular nucleus and other brain sites of the rat
12. Effects of synthetic ovine corticotropin-releasing factor, glucocorticoids, catecholamines, neurohypophysial peptides, and other substances on cultured corticotropic cells
13. Dopaminergic mediation of physiological changes in proopiomelanocortin messenger ribonucleic acid expression in the neurointermediate lobe of the rat pituitary
14. Structure and biosynthesis of pro-adrenocorticotropin/endorphin and related peptides
15. Prohormone-converting enzymes: Regulation and evaluation of function using antisense RNA
16. Distribution and regulation of the prohormone convertases PC1 and PC2 in the rat pituitary
17. The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing
18. Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptor
19. Antiproliferative role of dopamine: Loss of D2 receptors causes hormonal dysfunction and pituitary hyperplasia
20. Ontogeny of basal and regulated proopiomelanocortin-derived peptide secretion from fetal and neonatal pituitary intermediate lobe cells: Melanotrophs exhibit transient glucocorticoid responses during development
21. The basophil adenomas of the pituitary body and their clinical manifestations
22. The adrenal cortex
23. Mammalian neural and endocrine pro-protein and pro-hormone convertases belonging to the subtilisin family of serine proteinases
24. Tissue-specific do-paminergic regulation of the glucocorticoid receptor in the rat pituitary
25. Bioactive and immunoreactive adrenocorticotropin in normal equine pituitary and in pituitary of horses with Cushing's disease
26. Proopiomelanocortin peptides in normal pituitary, pituitary tumors and plasma of normal and Cushing's horses
27. The mechanism of suppressive action of bromocriptine on adrenocorticotropin secretion in patients with Cushing's disease and Nelson's syndrome