Reversing tetracycline resistance: A renaissance for the tetracycline family of antibiotics

Advances in Experimental Medicine and Biology

Volumn 456, Issue , 1998, Pages 17-25

  Levy, S B ^a   Nelson, M ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORTETRACYCLINE; DEMECLOCYCLINE; DOXYCYCLINE; METACYCLINE; MINOCYCLINE; OXYTETRACYCLINE; TETRACYCLINE; TETRACYCLINE DERIVATIVE;

ANTIBIOTIC RESISTANCE; BACTERIUM CONJUGATION; BACTERIUM TRANSDUCTION; BACTERIUM TRANSFORMATION; DRUG TRANSPORT; NONHUMAN; PRIORITY JOURNAL; REVIEW; TRANSPOSON;

BACTERIA (MICROORGANISMS);

EID: 0032226553     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-4897-3_3     Document Type: Review

References (21)

1. The Challenge of Antibiotic Resistance
2. Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in E. coli
3. Endogenous active efflux of norfloxacin in susceptible Escherichia coli
4. Active efflux mechanisms for antimicrobial resistance
5. Prevention of drug access to bacterial targets: Permeability barriers and active efflux
6. Streptococcal tetracycline resistance mediated at the level of protein synthesis
7. Active transport of calcium in inverted membrane vesicles of Escherichia coli
8. Energetics of tetracycline efflux system encoded by Tn10 in Escherichia coli
9. Transport of divalent cations with tetracycline as mediated by the transposon Tn10-encoded tetracycline resistance protein
10. Detection of an inducible membrane protein associated with R-factor-mediated tetracycline resistance
11. Two complementation groups mediate tetracycline resistance determined by Tn10
12. Intracistronic complementation of the tetracycline resistance membrane protein specified by Tn10
13. Interdomain hybrid Tet proteins confer tetracycline resistance only when derived from more closely related members of the tet gene family
14. Overproduction and purification of the Tn10-specified inner membrane tetracycline resistance protein Tet using fusions to β-galactosidase
15. Purification of the Tn10-specified tetracycline efflux antiporter TetA in a native state as a polyhistidine fusion protein
16. 1-ATPase
17. The N-terminal half of the Tn10-encoded tetracycline efflux protein TetA contains a functional dimerization domain
18. Inhibition of the tetracycline efflux antiport protein by 13-thio-substituted 5-hydroxy-6-deoxy tetracyclines
19. Molecular requirements for the inhibition of the tetracycline antiport protein and the effect of potent inhibitors on growth of tetracycline resistant bacteria