Are there significant gradients of PO2 in cells?

Advances in Experimental Medicine and Biology

Volumn 454, Issue , 1998, Pages 415-423

  Grinberg, Oleg Y ^a   James, Philip E ^a   Swartz, Harold M ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANE TRANSPORT; CONFERENCE PAPER; ELECTRON SPIN RESONANCE; MITOCHONDRION; OXYGEN CONSUMPTION; OXYGEN DIFFUSION; OXYGEN SATURATION; OXYGEN TRANSPORT; PRIORITY JOURNAL; TRANSPORT KINETICS; ANIMAL; ARTICLE; BIOLOGICAL MODEL; CELL FUNCTION; METABOLISM; PHAGOSOME; PRESSURE;

OXYGEN;

ANIMALS; CELL PHYSIOLOGY; MITOCHONDRIA; MODELS, BIOLOGICAL; OXYGEN; OXYGEN CONSUMPTION; PARTIAL PRESSURE; PHAGOSOMES;

EID: 0032217218     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-4863-8_50     Document Type: Conference Paper

References (14)

1. Clark A, Jr, Clark PAA. Local oxygen gradients near isolated mitochondria. Bioph J, 48:931-938, 1985.
2. Dewhirst MW, Secomb TW, Ong ET, Hsu R, Gross J.F. Determination of local oxygen consumption rates in tumors. Cancer Res, 54:3333-3336, 1994.
3. Dutta A, Popel AS. A theoretical analysis of intracellular oxygen diffusion. J Theor Biol, 176:433-445, 1995.
4. Glockner JF, Swartz HM, Pals MA. Oxygen Gradients in CHO Cells: Measurement and characterization by electron spin resonance. J Cell Physiol, 140:505-511, 1989.
5. Hitchman ML. Measurement of Dissolved Oxygen. Series Chemical Analysis, Eds. Elving PJ, Winefordner JD, John Wiley & Sons. 49:199, 1978.
6. James PE, Grinberg OY, Michaels G, Swartz HM. Intraphagosomal oxygen in stimulated macrophages. J Cell Physiol, 163:241-247, 1995.
7. 2 supply in hepatocytes. Am J Physiol, 247 (Cell Physiol.16):C83-C89, 1984.
8. 2 and ATP. Am. J. Physiol, 250 (Cell Physiol. 19):C663-C675, 1986.
9. Katz IR, Wittenberg JB, Wittenberg BA. Monoamine oxidase, an intracellular probe of oxygen pressure in isolated cardiac myocites, J Biol Chem, 259:7504-7509, 1984.
10. Kennedy FG, Jones DP. Oxygen dependence of mitochondrial function in isolated rat cardiac myocytes. Am J Physiol, 250 (Cell Physiol. 19):C374-C383, 1986.
11. Koyama T, Kinjo M, Araiso T. Oxygen diffusion through mitochondrial membranes. Adv Exp Med Biol, 248:763-767, 1989.
12. Robiolio M, Rumsey WL, Wilson DF. Oxygen diffusion and mitochondrial respiration in neuroblastoma cells. Am J Physiol, 256 (Cell Physiol.25):C1207-C1213, 1989.
13. Swartz HM. Measurements of intracellular concentrations of oxygen: experimental results and conceptual implications of an observed gradient between intracellular and extracellular concentration of oxygen. In: Oxygen Transport to Tissue XV Eds.: Vaupel P, Zander R, Bruley DF (Eds.) Plenum Publishing Corp., New York, NV, 799-806, 1994.
14. Zandi I, Turner CP. Diffusivity of oxygen in water. Chem Eng Sci, 25:517, 1970.