Stimulation of HCO3— secretion across cystic fibrosis pancreatic duct cells by extracellular ATP

NeuroSignals

Volumn 7, Issue 6, 1998, Pages 321-327

  Cheung, C Y ^a   Wang, X F ^a   Chan, H C ^a  

^a and Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics   (Hong Kong)

Author keywords

ATP; CFPAC 1; Cystic fibrosis; HCO3 secretion; Pancreatic duct; pH

Indexed keywords

ADENOSINE TRIPHOSPHATE; BICARBONATE; CALCIUM ION; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; ANTHRANILIC ACID DERIVATIVE; FENAMIC ACID;

ARTICLE; CELL CULTURE; CELL PH; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYSTIC FIBROSIS; HUMAN; HUMAN CELL; PANCREAS CELL; PANCREAS DUCT; SECRETION; DRUG ANTAGONISM; DRUG EFFECT; ION TRANSPORT; METABOLISM; PH;

ADENOSINE TRIPHOSPHATE; ANTHRANILIC ACIDS; BICARBONATES; CELLS, CULTURED; CHLORIDE CHANNELS; CYSTIC FIBROSIS; HUMANS; HYDROGEN-ION CONCENTRATION; ION TRANSPORT; PANCREATIC DUCTS;

EID: 0032217055     PISSN: 1424862X     EISSN: 14248638     Source Type: Journal    
DOI: 10.1159/000014555     Document Type: Article

References (17)

1. Dubyak GR, El-Moatassim C: Signal transduction via P2-purinergic receptors for extracellular ATP and other nucleotides. Am J Physiol 1993;265:C577-C606.
2. 2-purino-ceptors in the rat epididymis. Br J Pharmacol 1988;95:1315-1321.
3. −secretion in T84 cells. Am J Physiol 1992;262:C67-C74.
4. − channels in normal and cystic fibrosis airway epithelial cells by extracellular ATP. Proc Natl Acad Sci USA 1992;89: 1621-1625.
5. − channels. J Pharmacol Exp Ther 1993;264:210-216.
6. 2-purinergic receptors in human breast tumor cells: Coupling of intracellular calcium signalling to anion secretion. J Pharmacol Exp Ther 1993;265: 1499-1510.
7. Chan HC, Zhou WL, Fu WO, Wong PYD: Different regulatory pathways involved in ATP-stimulated chloride secretion in rat epididymal epithelium. J Cell Physiol 1995; 164: 271-276.
8. Hug M, Pahl C, Novak I: Effect of ATP, carbachol and other agonists on intracellular calcium activity and membrane voltage of pancreatic ducts. Pflügers Arch 1994;426:412-418.
9. Reisin IL, Prat AG, Abraham EH, Amara JF, Gregory RH, Ausiello DA, Cantiello HF: The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel. J Biol Chem 1994;269: 20584-20591.
10. Schwiebert EM, Egan ME, Hwang TH, Fulmer SB, Allen SS, Cutting GR, Guggino WB: CFTR regulates outwardly rectifying chloride channels through an autocrine mechanism involving ATP. Cell 1995;81: 1063-1073.
11. Chan HC, Cheung WT, Leung PY, Wu LJ, Cheng Chew SB, Ko WH, Wong PYD: Purinergic regulation of anion secretion by cystic fibrosis pancreatic duct cells. Am J Physiol 1996;271:C469-C477.
12. Riordan JR: The cystic fibrosis transmembrane conductance regulator. Annu Rev Physiol 1993;55: 609-630.
13. Schoumacher RA, Ram J, Iannuzzi MC, Bardbury NA, Wallace RW, Hon CT, Kelly DR, Schmid SM, Gelder FB, Rado TA, Frizzell RA: A cystic fibrosis pancreatic adenocarcinoma cell line. Proc Natl Acad Sci USA 1990;87:4012-4016.
14. Eidelman O, Guay-Broder C, Van Galen PJM, Jacobson KA, Fox C, Turner RJ, Cabantchik GI, Pollard HB: Al adenosine-receptor antagonists activate chloride efflux from cystic fibrosis cells. Proc Natl Acad Sci USA 1992;89:5563-5566.
15. − and fluid absorption by cultured cystic fibrosis (CFPAC-1) cells. Proc Natl Acad Sci USA 1993;90:4047-4051.
16. Chan HC, Law SH, Leung PS, Fu LXM, Wong PYD: Angiotensin II receptor type I-regulated anion secretion in cystic fibrosis pancreatic duct cells. J Membr Biol 1997; 156: 241-249.
17. Case RM, Argent BE: Pancreatic duct cell secretion: Control and mechanisms of transport; in Go VLW, DiMagno ER, Gardner JD, Lebenthal FP, Reber HA, Scheele GA (eds): The Pancreas, ed 2. New York, Raven, 1993, pp 1473-1497.