Detection of activated Caspase-3 (CPP32) in the vertebrate nervous system during development by a cleavage site-directed antiserum

Developmental Brain Research

Volumn 111, Issue 1, 1998, Pages 77-87

  Urase, Koko ^a   Fujita, Eriko ^a   Miho, Yasuko ^a   Kouroku, Yoriko ^a   Mukasa, Takeshi ^a   Yagi, Yuzou ^b   Momoi, Mariko Y ^c   Momoi, Takashi ^a  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b Research Institute of Life Science   (Japan)

^c JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis; Caspase 3; CPP32; Neuronal cell death; Program cell death; Site directed antiserum

Indexed keywords

CASPASE 3; CYSTEINE PROTEINASE; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN DEVELOPMENT; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVATION; MOUSE; NEUROEPITHELIUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPINAL GANGLION; TRIGEMINUS GANGLION;

ANIMALS; CASPASE 3; CASPASES; CEREBRAL CORTEX; EMBRYO; EMBRYONIC AND FETAL DEVELOPMENT; ENZYME ACTIVATION; GANGLIA, SPINAL; IMMUNE SERA; MICE; NERVOUS SYSTEM; TRIGEMINAL GANGLION;

EID: 0032213968     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(98)00124-2     Document Type: Article

References (48)

1. Alcantara S., Frisen J., Del Rio J.A., Soriano E., Barbacid M., Silos-Santiago I. TrkB signaling is required for postnatal survival of CNS neurons and protects hippocampal and motor neurons from axotomy-induced cell death. J. Neurosci. 17:1997;3623-3633.
2. Armstrong R.C., Aja T.J., Hoang K.D., Gaur S., Bai X., Alnemri E.S., Litwack G., Karanewsky D.S., Fritz L.C., Tomaselli K.J. Activation of the CED3/ICE-related protease CPP32 in cerebellar granule neurons undergoing apoptosis but not necrosis. J. Neurosci. 17:1997;553-562.
3. Barde Y.A. Trophic factors and neuronal survival. Neuron. 2:1989;1525-1534.
4. Barres B.A., Hart I.K., Coles H.S., Burne J.F., Voyvodic J.T., Richardson W.D., Raff M.C. Cell death and control of cell survival in the oligodendrocyte lineage. Cell. 70:1992;31-46.
5. Blaschke A.J., Staley K., Chun J. Widespread programmed cell death in proliferative and postmitotic regions of the fetal cerebral cortex. Development. 122:1996;1165-1174.
6. Chun J.J., Shatz C.J. Interstitial cells of the adult neocortical white matter are the remnant of the early generated subplate neuron population. J. Comp. Neurol. 282:1989;555-569.
7. Cowan W.M., Fawcett J.W., O'Leary D.D., Stanfield B.B. Regressive events in neurogenesis. Science. 225:1984;1258-1265.
8. Crowley C., Spencer S.D., Nishimura M.C., Chen K.S., Pitts-Meek S., Armanini M.P., Ling L.H., McMahon S.B., Shelton D.L., Levinson A.D., Philips H.S. Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell. 76:1994;1001-1011.
9. Cunningham T.J. Naturally occurring neuron death and its regulation by developing neural pathways. Int. Rev. Cytol. 74:1982;163-186.
10. Devereaux Q.L., Takahashi R., Salvesen G.S., Reed J.C. X-linked IAP is a direct inhibitor of cell-death proteases. Nature. 388:1997;300-304.
11. Elledge R.M., Lee W.H. Life and death by p53. Bio Essays. 17:1995;923-930.
12. Ellis R.E., Yuan J.Y., Horvitz H.R. Mechanisms and functions of cell death. Annu. Rev. Cell Biol. 7:1991;663-698.
13. Enoch T., Norbury C. Cellular responses to DNA damage: cell cycle checkpoints, apoptosis and the roles of p53 and ATM. Trends Biochem. Sci. 20:1995;426-430.
14. Fernandes-Alnemri T., Takahashi A., Armstrong R., Krebs J., Fritz L., Tomaselli K.J., Wang L., Yu Z., Croce C.M., Salveson G., Earnshaw W.C., Litwack G., Alnemri E.S. Mch3, a novel human apoptotic cysteine protease highly related to CPP32. Cancer Res. 55:1995;6045-6052.
15. Ferrer I., Tortosa A., Blanco R., Martin F., Serrano T., Planas A., Macaya A. Naturally occurring cell death in the developing cerebral cortex of the rat. Evidence of apoptosis-associated internucleosomal DNA fragmentation. Neurosci. Lett. 182:1994;77-79.
16. Fujita E., Kouroku Y., Miho Y., Tsukahara T., Ishiura S., Momoi T. Wortmannin enhances activation of CPP32 (Caspase-3) induced by TNF or anti-Fas. Cell Death Differ. 5:1998;289-297.
17. Gagliardini V., Fernandez P.-A., Lee R.K., Drexier H.C., Rotello R.J., Fishman M.C., Yuan J. Prevention of vertebrate neuronal death by the CrmA gene. Science. 263:1994;826-828.
18. Graham F.L., van der. Eb A.J. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology. 52:1973;456-467.
19. Jordan J., Galindo M.F., Prehn J.H., Weichselbaum R.R., Beckett M., Ghadge G.D., Roos R.P., Leiden J.M., Miller R.J. p53 expression induces apoptosis in hippocampal pyramidal neuron cultures. J. Neurosci. 17:1997;1397-1405.
20. Jacobson M.D., Weil M., Raff M.C. Programmed cell death in animal development. Cell. 88:1997;347-354.
21. Kikuchi H., Imajoh-Ohmi S. Activation and possible involvement of calpain, a calcium-activated cysteine protease, in down-regulation of apoptosis of human monoblast U937 cells. Cell Death Differ. 2:1995;195-199.
22. Kuida K., Zheng T.S., Na S., Kuan C., Yang D., Karasuyama H., Rakic P., Flavell R.A. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature. 384:1996;368-372.
23. Lee K.F., Li E., Huber L.J., Landis S.C., Sharpe A.H., Chao M.V., Jaenisch R. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell. 69:1992;737-749.
24. Liston P., Roy N., Tamai K., Lefebvre C., Baird S., Cherton-Horvat G., Farahani R., McLean M., Ikeda J.E., MacKenzie A., Korneluk R.G. Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes. Nature. 379:1996;349-353.
25. Milligan C.E., Prevette D., Yaginuma H., Homma S., Cardwell C., Fritz L.C., Tomaselli K.J., Oppenheim R.W., Schwartz L.M. Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro. Neuron. 15:1995;385-393.
26. Minichiello L., Klein R. TrkB and TrkC neurotrophin receptors cooperate in promoting survival of hippocampal and cerebellar granule neurons. Genes and Dev. 10:1996;2849-2858.
27. Motoyama N., Wang F., Roth K.A., Sawa H., Nakayama K., Nakayama K., Negishi I., Senju S., Zhang Q., Fujii S., Loh D.Y. Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice. Science. 267:1995;1506-1510.
28. Mukasa T., Urase K., Momoi Y.M., Kimura I., Momoi T. Specific expression of CPP32 in sensory neurons of mouse embryos and activation of CPP32 in the apoptosis induced by a withdrawal of NGF. Biochem. Biophys. Res. Commun. 231:1997;770-774.
29. Mukasa T., Kohroku Y., Tsukahara T., Kimura I., Momoi M., Momoi T. Wortmannin enhances CPP32-like activity during neuronal differentiation of P19 embryonal carcinoma cells induced by retinoic acid. Biochem. Biophys. Res. Commun. 232:1997;192-197.
30. Muzio M., Chinnaiyan A.M., Kischkel F.C., O'Rourke K., Shevchenko A., Ni J., Scaffidi C., Bretz J.D., Zhang M., Gentz R., Mann M., Krammer P.H., Peter M.E., Dixit V.M. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death-inducing signaling complex. Cell. 85:1996;817-827.
31. Ni B., Wu X., Du Y., Su Y., Hamilton-Byrd E., Rockey P.K., Rosteck P.Jr., Poirier G.G., Paul S.M. Cloning and expression of a rat brain interleukin-1beta-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons. J. Neurosci. 17:1997;1561-1569.
32. Nicholson D.W., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., Lazebnik Y.A., Munday N.A., Raju S.M., Smulson M.E., Yamin T.-T., Yu V.L., Miller D.K. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature. 376:1995;37-43.
33. Oppenheim R.W. Cyclic GMP and neurone death. Nature. 313:1985;248.
34. Oppenheim R.W. Cell death during development of the nervous system. Annu. Rev. Neurosci. 14:1991;453-501.
35. Parsadanian A.S., Cheng Y., Keller-Peck C.R., Holtzman D.M., Snider W.D. Bcl-XL is an antiapoptotic regulator for postnatal CNS neurons. J. Neurosci. 18:1998;1009-1019.
36. Saido T.C., Yokota M., Nagao S., Yamaura I., Tani E., Tsuchiya T., Suzuki K., Kawashima S. Spatial resolution of fodrin proteolysis in postischemic brain. J. Biol. Chem. 268:1993;25239-25243.
37. Saido T.C., Kawashima S., Tani E., Yokota M. Up- and down-regulation of calpain inhibitor polypeptide, calpastatin, in postischemic hippocampus. Neurosci. Lett. 227:1997;75-78.
38. Schlegel J., Peters I., Orrenius S., Miller D.K., Thornberry N.A., Yamin T.T., Nicholson D.W. CPP32/apoptosis is a key interleukin 1b converting enzyme-like protease involved in Fas-mediated apoptosis. J. Biol. Chem. 271:1996;1841-1844.
39. Smeyne R.J., Klein R., Schnapp A., Long L.K., Bryant S., Lewin A., Lira S.A., Barbacid M. Severe sensory and sympathetic neuropathies in mice carrying a disrupted trk/NGF receptor gene. Nature. 368:1994;246-249.
40. Snider W.D. Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell. 77:1994;627-638.
41. Spreafico R., Frassoni C., Arcelli P., Selvaggio M., De Biasi S. In situ labeling of apoptotic cell death in the cerebral cortex and thalamus of rats during development. J. Comp. Neurol. 363:1995;281-295.
42. Tewari M., Dixit V.M. Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus CrmA gene product. J. Biol. Chem. 270:1995;3255-3260.
43. D.G. Wilkinson, Whole mount in situ hybridization of vertebrate embryos, in: D.G. Wilkinson (Ed.), In Situ Hybridization: A Practical Approach. Oxford IRL Press, NY, 1992, pp. 75-83.
44. Williams R.W., Herrup K. The control of neuron number. Annu. Rev. Neurosci. 11:1988;423-453.
45. Wu X., Levine A.J. p53 and E2F-1 cooperate to mediate apoptosis. Proc. Natl. Acad. Sci. USA. 91:1994;3602-3606.
46. Xue D., Shaham S., Horvitz H.R. The Caenorhabditis elegans cell-death protein CED-3 is a cysteine protease with substrate specificities similar to those of the human CPP32 protease. Genes Dev. 10:1996;1073-1083.
47. Yuan J.-Y., Shaham S., Ledoux S., Ellis H.M., Horvitz H.R. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1beta-converting enzyme. Cell. 75:1993;641-652.
48. Zou H., Henzel W.J., Liu X., Lutschg A., Wang X. Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell. 90:1997;405-413.