Synthesis of benzanilide derivatives as dual acting agents with α1- adrenoceptor antagonistic action and steroid 5-α reductase inhibitory activity

Bioorganic and Medicinal Chemistry Letters

Volumn 8, Issue 21, 1998, Pages 2967-2972

  Yoshida, Kiyoshi ^a   Horikoshi, Yoichiro ^a   Eta, Masaaki ^a   Chikazawa, Jun ^a   Ogishima, Masayuki ^a   Fukuda, Yohichi ^a   Sato, Hiroki ^a  

^a ZERIA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Antagonist; Enzyme inhibitor; Hormones; Substituent effects

Indexed keywords

4 [2 [4 (4 ISOBUTYL ALPHA METHYLBENZYLOXY) 2,3 DIMETHYLBENZAMIDO]PHENOXY]BUTYRIC ACID; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ANDROSTANOLONE; BENZANILIDE DERIVATIVE; STEROID 5ALPHA REDUCTASE; STEROID 5ALPHA REDUCTASE INHIBITOR; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG SYNTHESIS; MALE; MUSCLE CONTRACTION; NONHUMAN; PROSTATE; RABBIT; STRUCTURE ACTIVITY RELATION;

ADRENERGIC ALPHA-ANTAGONISTS; ANILIDES; ANIMALS; CHOLESTENONE 5 ALPHA-REDUCTASE; ENZYME INHIBITORS; OXIDOREDUCTASES; RABBITS; RECEPTORS, ADRENERGIC, ALPHA-1; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0032212694     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(98)00538-1     Document Type: Article

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