Functional expression of TrkA receptors in hippocampal neurons

Journal of Neuroscience Research

Volumn 54, Issue 3, 1998, Pages 424-431

  Aibel, Lani ^a   Martin Zanca, Dionisio ^b   Perez, Pilar ^b   Chao, Moses V ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Hippocampal neurons; NGF receptors; SHC protein; Transfection

Indexed keywords

NERVE GROWTH FACTOR; NERVE GROWTH FACTOR RECEPTOR; TYROSINE; TYROSINE KINASE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL TYPE; EMBRYO; GENETIC TRANSFECTION; HIPPOCAMPUS; MOUSE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAT; RECEPTOR UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; CELL LINE; CELL SIZE; CELLS, CULTURED; HIPPOCAMPUS; HUMANS; ISOENZYMES; MUTATION; NERVE GROWTH FACTORS; NEURITES; NEURONS; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PROTEINS; PROTO-ONCOGENE PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, CILIARY NEUROTROPHIC FACTOR; RECEPTOR, TRKA; RECEPTORS, NERVE GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSFECTION; TYROSINE;

EID: 0032212362     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19981101)54:3<424::AID-JNR13>3.0.CO;2-6     Document Type: Article

References (33)

1. Barbacid M (1994): The trk family of neurotrophin receptors. J Neurobiol 25:1386-1403.
2. Casaccia-Bonnefil, Kong H. Chao MV (1998): Neurotrophins: The biological paradox of survival factors eliciting apoptosis. Cell Death Differentiation 5:357-364.
3. Cellerino A (1996): Expression of messenger RNA coding for the nerve growth factor receptor trkA in the hippocampus of the adult rat. Neuroscience 70:613-616.
4. Clary DO, Weskamp G, Austin LR, Reichardt LF (1994): TrkA cross-linking mimics neuronal responses to nerve growth factor. Mol Biol Cell 5:549-563.
5. Coulier F, Kumar R, Ernst M, Klein R, Martin-Zanca D, Barbacid M (1990): Human trk oncogenes activated by point mutation, in-frame deletion, and duplication of the tyrosine kinase domain. Mol Cell Biol 10:4202-4210.
6. Crowley C. Spenser SD, Nishimura MC, Chen KS. Pitts-Meek S, Armanini MP, Ling LH, McMahon SB, Shelton DL, Levinson AD, Philips HS (1994): Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons. Cell 76:1001-1012.
7. Dikic E, Batzer AG, Blaikie P, Obermeier A, Ullrich A, Schlessinger J, Margolis B (1995): She binding to nerve growth factor receptor is mediated by the phosphotyrosine interaction domain. J Biol Chem 270:15125-15129.
8. Dudek H, Datta SR, Franke TF, Birnbaum MJ, Yao R. Cooper GM, Segal RA, Kaplan DR, Greenberg ME (1997): Regulation of neuronal survival by the serine-threonine protein kinase Akt. Science 275:661-668.
9. Gabcllini N, Minozzi M-C, Leon A, Toso RD (1992): Nerve growth factor transcriptional control of c-fos promoter transfected in cultured spinal sensory neurons. J Cell Biol 118:131-138.
10. Greene LA. Kaplan DR (1995): Early events in neurotrophin signaling via Trk and p75 receptors. Curr Topics Neurobiol 5:579-587.
11. Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK, Wong AJ (1996): A Grb2-associated docking protein in EGF- and insulin-receptor signalling. Nature 379:560-564.
12. Holgado-Madruga M, Moscatello DK, Emlet DR, Dieterich R, Wong AJ (1997): Grb2-associated binder-1 mediates phosphatidylinositol 3-kinase activation and the promotion of cell survival by nerve growth factor. Proc Natl Acad Sci USA 94:13419-12424.
13. Kaplan DR, Hempstead BL, Martin-Zanca D, Chao MV, Parada LF (1991): The trk proto-oncogene product: A signal transducing receptor for nerve growth factor. Science 252:554-558.
14. Loeb DM, Stephens RM, Copeland T, Kaplan DR, Greene LA (1994): A trk nerve growth-factor (NGF) receptor point mutation affecting interaction with phospholipase c-gamma-1 abolishes NGF-promoted peripherin induction but not neurite outgrowth. J Biol Chem 269:8901-8910.
15. Mahadeo D, Kaplan L, Chao MV, Hempstead BL (1994): High affinity nerve growth factor binding displays a faster rate of association than p140(trk) binding - Implications for multisubunit polypeptide receptors. J Biol Chem 269:6884-6891.
16. Mandiyan V, O'Brien R, Zhou M, Margolis B, Lemmon MA, Sturtevant JM, Schlessinger J (1996): Thermodynamic studies of SHC phosphotyrosine interaction domain recognition of the NPXpY motif. J Biol Chem 271:4770-4775.
17. Martin-Zanca D, Oskam, R, Mitra G, Copeland T, Barbacid M (1989): Molecular and biochemical characterization of the human trk proto-oncogene. Mol Cell Biol 9:24-33.
18. Minichiello L, Casagranda F, Tatche RS, Stucky CL, Postigo A, Lewin GR, Davies AM, Klein R (1998): Point mutation in trkB causes loss of NT-4-dependent neurons without major effects on diverse BDNF responses. Neuron 21:335-345.
19. Obermeier A, Halfter H, Wiesmuller K-H, Jung G, Schlessinger J, Ullrich A (1993a): Tyrosine 785 is a major determinant of trk-substrate interaction. EMBO J 12:933-941.
20. Obermeier A, Lammers R, Wiesmuller K-H, Jung G, Schlessinger J, Ullrich A (1993b): Identification of Trk binding sites for SHC and PI-3'-kinase and formation of a multimeric signaling complex. J Biol Chem 268:22963-22966.
21. Obermeier A, Bradshaw RA, Seedorf K, Choidas A, Schlessinger J, Ullrich A (1994): Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC-γ. EMBO J 13:1585-1590.
22. Peng X, Greene LA, Kaplan DR, Stephens RM (1995): Deletion of a conserved juxtamembrane sequence in Trk abolishes NGF-promoted neuritogenesis. Neuron 15:395-406.
23. Perez P. Coll PM, Hempstead BL, Martin-Zanca D, Chao MV (1995): NGF binding to the trk tyrosine kinase receptor requires the extracellular immunoglobulin-like domains. Mol Cell Neurosci 6:97-105.
24. Rozakis-Adcock, McGlade J, Mbamalu G, Pelicci G, Daly R, Li W, Batzer A, Thomas S, Brugge J, Pelicci PG, Schlessinger J, Pawson T (1992): Association of the SHC and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature 360:689-692.
25. Segal RA, Bhattacharyya A., Rua LA, Alberta JA, Stephens RM, Kaplan DR, Stiles CD (1996): Differential utilization of Trk autophosphorylation sites. J Biol Chem 271:20175-20181.
26. Smeyne RJ. Klein R, Schnapp A, Long LK, Bryant S, Lewin A, Lira SA, Barbacid M (1994): Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene. Nature 368:246-249.
27. Snider WD (1994): Functions of the neurotrophins during nervous-system development - What the knockouts are teaching us. Cell 77:627-638.
28. Songyang Z, Margolis B, Chaudhuri M, Shoelson SE. Cantley LC (1995): The phosphotyrosine interaction domain of SHC recognizes tyrosine-phosphorylated NPXY motif. J Biol Chem 270: 14863-14866.
29. Stephens RM. Loeb DM, Copeland TD, Pawson T, Greene LA, Kaplan DR (1994): Trk receptors use redundant signal-transduction pathways involving SHC and PLC-gamma-1 to mediate NGF responses. Neuron 12:691-705.
30. Urfer R, Tsoulfas P, O'Connell L, Shelton DL, Parada LF, Presta LG (1995): An immmunoglobulin-like domain determines the specificity of neurotrophin receptors. EMBO J 14:2795-2805.
31. Yoon SO, Soltoff S, Chao MV (1997): A dominant role of the juxtamembrane region of the TrkA nerve growth factor receptor during neuronal cell differentiation. J Biol Chem 272:23231-23238.
32. Zafra F, Hengerer B, Leibrock J, Thoenen H, Lindholm D (1990): Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors. EMBO J 9:3545-3550.
33. Zhou M-M. Ravichandran KS, Olejniczak ET, Petros AM, Meadows RP, Sattler M, Harlan JE, Wade WS, Burakoff SJ, Fesik SW (1995): Structure and ligand recognition of the phosphotyrosine binding domain of Shc. Nature 378:584-591.