A multicenter prospective study on the risk of acquiring liver disease in anti-hepatitis C virus negative patients affected from homozygous β- thalassemia

Blood

Volumn 92, Issue 9, 1998, Pages 3460-3464

  Prati, Daniele ^a   Zanella, Alberto ^b   Farma, Elena ^b   De Mattei, Claudia ^b   Bosoni, Patrizia ^b   Zappa, Manuela ^b   Picone, Alessandra ^b   Mozzi, Fulvio ^b   Rebulla, Paolo ^b   Cappellini, Maria Domenica ^b   Allain, Jean Pierre ^b   Sirchia, Girolamo ^b  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; FERRITIN; HEPATITIS C ANTIBODY;

ADOLESCENT; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; BLOOD TRANSFUSION; CHILD; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENZYME IMMUNOASSAY; FEMALE; FERRITIN BLOOD LEVEL; FOLLOW UP; HEPATITIS C VIRUS; HUMAN; INFANT; INFECTION RISK; LIVER DYSFUNCTION; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; PRIORITY JOURNAL; SEROCONVERSION; SIDEROSIS; THALASSEMIA MAJOR; VIRUS TRANSMISSION;

EID: 0032212245     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v92.9.3460.421k14_3460_3464     Document Type: Article

References (30)

1. Zurlo MF, De Stefane P, Borgna-Pignatti C, Di Palma A, Piga A, Melevendi C, Di Gregorio F, Burattini MG, Terzoli S: Survival and causes of death in thalassaemia major. Lancet 2:27, 1989
2. Rebulla P, Mozzi F, Contino G, Locatelli E, Sirchia G: Antibody to hepatitis C virus in 1,305 Italian multiply transfused thalassaemics: Comparison of first and second generation tests. Transfus Med 2:69, 1992
3. Olivieri NF, Brittenham GM: Iron-chelating therapy and the treatment of thalassemia. Blood 89:739, 1997
4. Aach RD, Stevens CE, Hollinger FB: Hepatitis C virus infection in post-transfusion hepatitis -an analysis with first- and secondgeneration assays. N Engl J Med 325:1325, 1991
5. Donahue JG, Muñoz A, Ness PM, Brown DE, Yawn DH, McAllister HA, Reitz BA, Nelson KE: The declining risk of posttransfusion hepatitis C virus infection. N Engl J Med 327:369, 1992
6. Nelson KE, Donahue JG, Stambolis V: Post-transfusion hepatitis C virus infection (letter). N Engl J Med 327:1601, 1992
7. Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ for the Retrovirus Epidemiology Donor Study: The risk of transfusiontransmitted viral infections. N Engl J Med 334:1685, 1996
8. Blajchman MA, Bull SB, Feinman, SVTI: Post-transfusion hepatitis: Impact of non-A, non-B hepatitis surrogate tests. Lancet 345:21, 1995
9. Alter HJ, Nakatsuji Y, Melpolder J, Wages J, Wesley R, Shih JWK, Kim JP: The incidence of transfusion-associated hepatitis G virus infection and its relation to liver disease. N Engl J Med 336:747, 1997
10. Alter HJ: The cloning and clinical implications of HGV and HGBV-C. N Engl J Med 334:1536, 1996
11. Simons JN, Leary TP, Dawson GJ, Pilot-Matias TJ, Muerhoff AS, Schlauder GG, Desai SM, Mushahwar IK: Isolation of novel virus-like sequences associated with human hepatitis. Nat Med 1:564, 1995
12. Linnen J, Wages J Jr, Zhang-Keck ZY, Fry KE, Krawczynski KZ, Alter H, Koonin E, Gallagher M, Alter M, Hadziyannis S, Karayiannis P, Fung K, Nakatsuji Y, Shih JW, Young L, Piatak M Jr, Hoover C, Fernandez J, Chen S, Zou JC, Morris T, Hyams KC, Ismay S, Lifson JD, Hess G, Foung SKH, Thomas H, Bradley D, Margolis H, Kim JP: Molecular cloning and disease association of hepatitis G virus: A transfusion-transmissible agent. Science 271:505, 1996
13. Wang JT, Tsai FC, Lee CZ, Chen PJ, Sheu JC, Wang TH, Chen DS: A prospective study of transfusion-transmitted GB virus C infection: Similar frequency but different clinical presentation compared with hepatitis C virus. Blood 88:1881, 1996
14. Prati D, Zanella A, Bosoni P, Rebulla P, Farma E, De Mattei C, Capelli C, Mozzi F, Gallisai D, Magnano C, Melevendi C, Sirchia G, for the Cooleycare cooperative group: The incidence and natural course of transfusion-associated hepatitis G virus infection in a cohort of thalassemic patients. Blood 91:774, 1998
15. Vrielink H, van der Poel CL, Reesink HW, Zaaijer HL, Lelie PN: Transmission of hepatitis C virus by anti-HCV-negative blood transfusion. Case report. Vox Sang 68:55, 1995
16. Prati D, Capelli C, Silvani C, De Mattei C, Bosoni P, Pappalet tera M, Mozzi F, Colombo M, Zanella A, Sirchia G: The incidence and risk factors of community-acquired hepatitis C in a cohort of Italian blood donors. Hepatology 25:702, 1997
17. Allander T, Gruber A, Naghavi M, Beyene A, Söderström T, Björkholm M, Grillner L, Persson MA: Frequent patient-to-patient transmission of hepatitis C virus in a haematology ward. Lancet 345:603, 1995
18. Prati D, Capelli C, Rebulla P, Mozzi F, Bosoni P, De Mattei C, Sirchia G, for the Cooleycare cooperative group: The current risk of retroviral infections transmitted by transfusion in patients who have undergone multiple transfusions. Arch Intern Med 158:1566, 1998
19. Rebulla P, Modell B: Transfusion requirements and effects in patients with thalassaemia major. Lancet 337:277, 1991
20. Mozzi F, Rebulla P, Lillo F, Varnier OE, Biadati C, Calcagno L, Melotti S, Sirchia G and the Cooleycare cooperative group: HIV and HTLV infections in 1305 transfusion-dependent thalassemics in Italy. AIDS 6:505, 1992
21. Prati D, Capelli C, Zanella A, Mozzi F, Bosoni P, Pappalettera M, Zanuso F, Vianello L, Locatelli E, De Fazio C, Ronchi G, Del Ninno E, Colombo M, Sirchia G: Influence of different hepatitis C virus genotypes on the course of asymptomatic hepatitis C virus infection. Gastroenterology 110:178, 1996
22. Prati D, Capelli C, Zanella A, Bosoni P, De Mattei C, Mozzi F, Donato MF, Colombo M, Milani S, Sirchia G: Asymptomatic hepatitis G virus infection in blood donors. Transfusion 37:1200, 1997
23. Di Marco V, Lo lacono O, Almasio P, Ciaccio C, Capra M, Rizzo M, Malizia R, Maggio A, Fabiano C, Barbaria F, Craxì A: Long-term efficacy of α-interferon in β-thalassemics with chronic hepatitis C. Blood 90:2207, 1997
24. Sampietro M, Corbetta N, Cerino M, Fabiani P, Ticozzi A, Orlandi A, Lunghi G, Fargion S, Fiorelli G, Cappellini MD: Prevalence and clinical significance of hepatitis G virus infection in adult betathalassaemia major patients. Br J Haematol 97:904, 1997
25. Dwyer J, Wood C, McNamara J, Williams A, Andiman W, Rink L, O'Connor T, Pearson H: Abnormalities in the immune system of children with beta-thalassemia major. Clin Exp Immunol 68:621, 1987
26. Bonkovsky H, Banner BF, Rothman AL: Iron and chronic viral hepatitis. Hepatology 25:759, 1997
27. Olivieri NF, Nathan DJ, MacMillan JH, Wayne AS, Liu PP, McGee A, Martin M, Koren G, Cohen AR: Survival in medically treated patients with homozygous β-thalassemia. N Engl J Med 331:574, 1994
28. Alter HJ, Purcell RH, Shin JW, Melpolder JC, Houghton M, Choo QL, Kuo G: Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N Engl J Med 321:1494, 1989
29. Alter MJ, Margolis HS, Krawcynski K, Judson FN, Mares A, Alexander WJ, Hu PY, Miller JK, Gerber MA, Sampliner RE, Meeks EL, Beach MJ: The natural history of community-acquired hepatitis C in the United States. N Engl J Med 327:1899, 1992
30. De Filippi F, Colombo M, Rumi MG, Tradati F, Prati D, Zanella A, Mannucci PM: High rates of hepatitis G virus infection in multitransfused patients with hemophilia. Blood 90:4634, 1997