Catecholamine secretion from bovine adrenal chromaffin cells induced by the dextrorotatory isomer of anatoxin-a

General Pharmacology

Volumn 31, Issue 5, 1998, Pages 737-740

  Dar, Dalit E ^a   Zinder, Oren ^b  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b NONE

Author keywords

(+)Anatoxin ; Acetylcholine; Catecholamines; Chromaffin cells; Nicotine; Oxotremorine M

Indexed keywords

ACETYLCHOLINE; ADRENALIN; ANATOXIN A; ATROPINE; CALCIUM ION; EGTAZIC ACID; MECAMYLAMINE; NICOTINE; NICOTINIC RECEPTOR; NORADRENALIN; OXOTREMORINE; VERAPAMIL;

ANIMAL CELL; ARTICLE; CALCIUM TRANSPORT; CATECHOLAMINE RELEASE; CATTLE; CHROMAFFIN CELL; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG POTENCY; ENANTIOMER; NONHUMAN; PRIORITY JOURNAL;

ADRENAL MEDULLA; ANIMALS; BACTERIAL TOXINS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CATECHOLAMINES; CATTLE; CHELATING AGENTS; CHROMAFFIN CELLS; DOSE-RESPONSE RELATIONSHIP, DRUG; EGTAZIC ACID; MARINE TOXINS; MICROCYSTINS; MUSCARINIC ANTAGONISTS; NEUROTOXINS; NICOTINIC AGONISTS; NICOTINIC ANTAGONISTS; STEREOISOMERISM; TIME FACTORS; VERAPAMIL;

EID: 0032212097     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(98)00113-X     Document Type: Article

References (22)

1. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Ann. Biochem. 72:1976;248-254.
2. Brown W.M., Pazoles C.J., Creutz C.E., Auerbach D., Pollard H.B. Role of anions on parathyroid hormone release from dispersed bovine parathyroid cells. Proc. Natl. Acad. Sci. USA. 75:1978;876-880.
3. Carmichael W.W., Biggs D.F., Gorham P.R. Toxicology and pharmacology action of. Anabaena flos-aquae. toxin.(Science 187):1975;542-544.
4. Carmichael W.W., Biggs D.F., Peterson M.A. Pharmacology of anatoxin-a, produced by the freshwater cyanophyte Anabaena flos-aquae NRC-44-1. Toxicon. 17:1979;229-236.
5. Criado M., Alamo L., Navarro A. Primary structure of an agonist binding subunit of the nicotinic acetylcholine receptor from bovine adrenal chromaffin cells. Neurochem Res. 17:1992;281-287.
6. Dar D.E., Zinder O. Strychnine affects catecholamine secretion from bovine adrenal medulla chromaffin cells. Naunyn-Schmiedberg's Arch. Pharmac. 352:1995;11-16.
7. Devlin J.P., Edwards E., Gorham P.R., Hunter H.R., Pike R.K., Stavrric B. Anatoxin-a, a toxic alkaloid from Anabaena flos-aquae NRC-44h. Can. J. Chem. 55:1977;1367-1371.
8. Fenwick E.M., Marty A., Neher E. A patch clamp study of bovine chromaffin cells and their sensitivity to acetylcholine. J. Physiol. 331:1982;577-597.
9. Greenberg A., Zinder O. α- and β-Receptor control of catecholamine secretion from isolated adrenal medulla cells. Cell Tissue Res. 226:1982;655-665.
10. 3H-nicotine binding on bovine adrenal chromaffin cells. J. Neurosci. 8:1988;1436-1446.
11. Huber C.S. The crystal structure and absolute configuration of 2,9-diacetyl-9-azabicyclo [4,2,1]non 2,3-ene. Acta Crystallogr. Sect. B Struct. Crystallogr. Cryst. Chem. 28:1972;2577-2582.
12. Koskinen A.M., Rapoport H. Synthetic and conformational studies on anatoxin-a. a potent acetylcholine agonist J. Med. Chem. 28:1985;1301-1309.
13. 3H]nicotine binding assay. Naunyn-Schmiedeberg's Arch. Pharmac. 345:1992;363-369.
14. Molloy L., Wonnacott S., Gallagher T., Brough P.A., Livett B.G. Anatoxin-a is a potent agonist of the nicotinic acetylcholine receptor of bovine adrenal chromaffin cells. Eur. J. Pharmac. 289:1995;447-453.
15. Muller T.H., Unsicker K. High-performance liquid chromatography with electrochemical detection as a highly efficient tool for studying catecholamine system. quantification of noradrenaline, adrenaline and dopamine in cultured adrenal medullary cells J. Neurosci. Methods. 4:1981;39-52.
16. Nooney J.M., Peters J.A., Lambert J.J. A patch clamp study of the nicotinic acetylcholine receptor of bovine adrenomedullary chromaffin cells in culture. J. Physiol. 455:1992;503-527.
17. Oka M., Isosaki M. and Watanabe J. (1982) Calcium flux and catecholamine release in isolated bovine adrenal medullary cells: effects of nicotinic and muscarinic stimulation: In Advances in the Biosciences: Synthesis, Storage and Secretion of Adrenal Catecholamine, Vol. 36, pp. 29-36. Pergamon, Oxford.
18. Pollard H.B., Pazoles C.J., Hoffman P.G., Zinder O., Nikoijevik O. Regulation of release from isolated adrenergic secretory vesicles by ATP-mediated changes in transmembrane potential and ion permeability. Cell. Neurobiol. 250:1977;259-266.
19. Shirvan M.H., Pollard H.B., Heldman E. Mixed nicotinic and muscarinic features of cholinergic receptor coupled to secretion in bovine chromaffin cells. Proc. Natl. Acad. Sci. USA. 88:1991;4860-4864.
20. Spivac C.E., Witkop B., Albuquerque E.X. Anatoxin-a. a novel, potent agonist at the nicotinic receptor Mol. Pharmac. 18:1980;384-394.
21. Swanson K.L., Allen C.N., Arostam R.S., Rapoport H., Albuquerque E.X. Molecular mechanism of the potent and stereo selective nicotinic receptor agonist (+)anatoxin-a. Mol. Pharmac. 29:1986;250-257.
22. Zinder O. and Pollard H. B. (1980) The chromaffin granule: recent studies leading to a functional model for exocytosis. In Essays in Neurochemistry and Neuropharmacology, Vol. 4. (Edited by Youdim M. B. H., Lovenberg, W., Sharman D. F. and Lagnado J. R.), pp. 125-162. Wiley.