Microbial flora of the cervix assessed at the time of embryo transfer adversely affects in vitro fertilization outcome

Fertility and Sterility

Volumn 70, Issue 5, 1998, Pages 866-870

  Fanchin, Renato ^a,b   Harmas, Amar ^a   Benaoudia, Farida ^a   Lundkvist, Ulrika ^a   Olivennes, François ^a   Frydman, René ^a  

^a HÔPITAL ANTOINE BÉCLÈRE   (France)

^b Hop Antoine Béclère ^*  (France)

Author keywords

Catheters; Cervical flora; Embryo transfer; Implantation; In vitro fertilization; Infection

Indexed keywords

ADULT; ARTICLE; BACTERIAL FLORA; CONTAMINATION; EMBRYO DEVELOPMENT; EMBRYO TRANSFER; FEMALE; FERTILIZATION IN VITRO; GENITAL TRACT INFECTION; HUMAN; MAJOR CLINICAL STUDY; NIDATION; OUTCOMES RESEARCH; PREGNANCY COMPLICATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEXUALLY TRANSMITTED DISEASE; UTERINE CERVIX MUCOSA;

ADULT; BACTERIOLOGICAL TECHNIQUES; CERVIX UTERI; EMBRYO IMPLANTATION; EMBRYO TRANSFER; EVALUATION STUDIES; FEMALE; FERTILIZATION IN VITRO; HUMANS; PREGNANCY; PREGNANCY OUTCOME; PROSPECTIVE STUDIES;

EID: 0032211846     PISSN: 00150282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0015-0282(98)00277-5     Document Type: Article

References (16)

1. Tatbibzadeh S., Babaknia A. The signals and molecular pathways involved in implantation, a symbiotic interaction between blastocyst and endometrium involving adhesion and tissue invasion. Hum Reprod. 10:1995;1579-1602.
2. Paulson R.J., Sauer M.V., Lobo R.A. Factors affecting embryo implantation after human in vitro fertilization a hypothesis . Am J Obstet Gynecol. 163:1990;2020-2023.
3. Grillo J.M., Gamerre M., Lacroix O., Noizet A., Vitry G. Influence of the morphological aspect of embryos obtained by in vitro fertilization on their implantation rate. J In Vitro Fert Embryo Transfer. 6:1991;317-321.
4. Navot D., Anderson T.L., Droesch K., Scott R.T., Kreiner D., Rosenwaks Z. Hormonal manipulation of endometrial maturation. J Clin Endocrinol Metab. 68:1989;801-807.
5. Lessey B.A., Damjanovich L., Coutifaris C., Castelbaum A., Albelda S.M., Buck C.A. Integrin adhesion molecules in the human endometrium. Correlation with the normal and abnormal menstrual cycle. J Clin Invest. 90:1992;188-195.
6. Westrom L. Effect of acute pelvic inflammatory disease on fertility. Am J Obstet Gynecol. 121:1975;707-713.
7. Faro S. Chlamydia trachomatis female pelvic infection . Am J Obstet Gynecol. 164:1991;1767-1770.
8. Witkin S.S., Sultan K.M., Neal G.S., Jeremias J., Grifo J.A., Rosenwaks Z. Unsuspected Chlamydia trachomatis infection and in vitro fertilization outcome. Am J Obstet Gynecol. 171:1994;1208-1214.
9. Witkin S.S., Kligman I.I., Grifo J.A., Rosenwaks Z. Chlamydia trachomatis detected by polymerase chain reaction in cervices of culture-negative women correlates with adverse in vitro fertilization outcome. J Infect Dis. 17:1995;1657-1659.
10. Bartlett J.G., Moon N.E., Goldstein P.R., Goren B., Onderdonk A.B., Polk B.F. Cervical and vaginal bacterial flora ecologic niches in the female lower genital tract . Am J Obstet Gynecol. 130:1978;658-661.
11. Egbase P.E., al-Sharhan M., al-Othman S., al-Mutawa M., Udo E.E., Grudzinskas J.G. Incidence of microbial growth from the tip of the embryo transfer catheter after embryo transfer in relation to clinical pregnancy rate following in-vitro fertilization and embryo transfer. Hum Reprod. 11:1996;1687-1689.
12. Czernobilsky B. Endometritis and infertility. Fertil Steril. 30:1978;119-130.
13. Nishikawa Y. Adherence of Escherichia coli in pathogenesis of endometritis and effects of estradiol examined by scanning electron microscopy. Infect Immun. 47:1985;318-321.
14. Reguera J.A., Baquero F., Pérez-Díaz J.C., Martínez J.L. Factors determining resistance to beta-lactam combined with beta-lactamase inhibitors in Escherichia coli. J Antimicrob Chemother. 27:1991;569-575.
15. Watt B., Goldacre M.J., Loudon N., Annat D.J., Harris R.I., Vessey M.P. Prevalence of bacteria in the vagina of normal young women. Br J Obstet Gynaecol. 88:1981;588-595.
16. Winberg J., Herthelius-Elman M., Mollby R., Nord C.E. Pathogenesis of urinary tract infection - experimental studies of vaginal resistance to colonization. Pediatr Nephrol. 7:1993;509-514.