메뉴 건너뛰기




Volumn 154, Issue 1, 1998, Pages 193-198

Overexpression of HA-Bax but not Bcl-2 or Bcl-X(L) attenuates 6- hydroxydopamine-induced neuronal apoptosis

Author keywords

6 hydroxydopamine; Apoptosis; Bax; Caspase; Dopaminergic neuron

Indexed keywords

OXIDOPAMINE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL X;

EID: 0032211304     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1998.6923     Document Type: Article
Times cited : (32)

References (41)
  • 1
    • 0030273295 scopus 로고    scopus 로고
    • Mitochondria, free radicals, and neurodegeneration
    • Beal M. F. Mitochondria, free radicals, and neurodegeneration. Curr. Opin. Neurobiol. 6:1996;661-666.
    • (1996) Curr. Opin. Neurobiol. , vol.6 , pp. 661-666
    • Beal, M.F.1
  • 5
    • 0001213485 scopus 로고
    • Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinones
    • Doroshow J. H. Role of hydrogen peroxide and hydroxyl radical formation in the killing of Ehrlich tumor cells by anticancer quinones. Proc. Natl. Acad. Sci. USA. 83:1986;4514-4518.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 4514-4518
    • Doroshow, J.H.1
  • 8
    • 0029845140 scopus 로고    scopus 로고
    • Animal models of Parkinson's disease: An empirical comparison with the phenomenology of the disease in man
    • Gerlach M., Riederer P. Animal models of Parkinson's disease: An empirical comparison with the phenomenology of the disease in man. J. Neural Transm. 103:1996;987-1041.
    • (1996) J. Neural Transm. , vol.103 , pp. 987-1041
    • Gerlach, M.1    Riederer, P.2
  • 9
    • 0030614642 scopus 로고    scopus 로고
    • Mechanism of 6-hydroxydopamine neurotoxicity
    • Glinka Y., Gassen M., Youdim M. B. Mechanism of 6-hydroxydopamine neurotoxicity. J. Neural Transm. 50:1997;55-66.
    • (1997) J. Neural Transm. , vol.50 , pp. 55-66
    • Glinka, Y.1    Gassen, M.2    Youdim, M.B.3
  • 10
    • 0028893492 scopus 로고
    • Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death
    • Greenlund L. J. S., Deckwerth T. L., Johnson E. M. Jr. Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death. Neuron. 14:1995;303-315.
    • (1995) Neuron , vol.14 , pp. 303-315
    • Greenlund, L.J.S.1    Deckwerth, T.L.2    Johnson E.M., Jr.3
  • 11
    • 0024595042 scopus 로고
    • Reexamination and further development of a precise and rapid dye method for measuring cell growth/cell kill
    • Hansen M. B., Nielson S. E., Berg K. Reexamination and further development of a precise and rapid dye method for measuring cell growth/cell kill. J. Immunol. Methods. 119:1989;203-210.
    • (1989) J. Immunol. Methods , vol.119 , pp. 203-210
    • Hansen, M.B.1    Nielson, S.E.2    Berg, K.3
  • 12
    • 0025204548 scopus 로고
    • Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
    • Hockenbery D. M., Nunez G., Milliman C., Schreiber R. D., Korsmeyer S. J. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature. 348:1990;334-336.
    • (1990) Nature , vol.348 , pp. 334-336
    • Hockenbery, D.M.1    Nunez, G.2    Milliman, C.3    Schreiber, R.D.4    Korsmeyer, S.J.5
  • 14
    • 0028939139 scopus 로고
    • Programmed cell death and Bcl-2 protection in very low oxygen
    • Jacobson M. D., Raff M. C. Programmed cell death and Bcl-2 protection in very low oxygen. Nature. 374:1995;814-816.
    • (1995) Nature , vol.374 , pp. 814-816
    • Jacobson, M.D.1    Raff, M.C.2
  • 15
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson M. D., Weil M., Korsmeyer S. J. Programmed cell death in animal development. Cell. 88:1997;347-354.
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Korsmeyer, S.J.3
  • 19
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer G. The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nature Med. 3:1997;614-620.
    • (1997) Nature Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 20
    • 0031027178 scopus 로고    scopus 로고
    • Early developmental destruction of terminals in the striatal target induces apoptosis in dopaminergic neurons of the substantia nigra
    • Marti M. J., James C. J., Oo T. F., Kelly W. J., Burke R. E. Early developmental destruction of terminals in the striatal target induces apoptosis in dopaminergic neurons of the substantia nigra. J. Neurosci. 17:1997;2030-2039.
    • (1997) J. Neurosci. , vol.17 , pp. 2030-2039
    • Marti, M.J.1    James, C.J.2    Oo, T.F.3    Kelly, W.J.4    Burke, R.E.5
  • 21
    • 0029125701 scopus 로고
    • Protease activation during apoptosis: Death by a thousand cuts
    • Martin S. J., Green D. R. Protease activation during apoptosis: death by a thousand cuts. Cell. 82:1995;349-352.
    • (1995) Cell , vol.82 , pp. 349-352
    • Martin, S.J.1    Green, D.R.2
  • 22
    • 0029670682 scopus 로고    scopus 로고
    • Bax promotes neuronal survival and antagonises the survival effects of neurotrophic factors
    • Middleton G., Nunez G., Davies A. M. Bax promotes neuronal survival and antagonises the survival effects of neurotrophic factors. Development. 122:1996;695-701.
    • (1996) Development , vol.122 , pp. 695-701
    • Middleton, G.1    Nunez, G.2    Davies, A.M.3
  • 23
    • 0029942337 scopus 로고    scopus 로고
    • Histochemical detection of apoptosis in Parkinson's disease
    • Mochizuki H., Goto K., Mori H., Mizuno Y. Histochemical detection of apoptosis in Parkinson's disease. J. Neurol. Sci. 137:1996;120-123.
    • (1996) J. Neurol. Sci. , vol.137 , pp. 120-123
    • Mochizuki, H.1    Goto, K.2    Mori, H.3    Mizuno, Y.4
  • 25
    • 0010306733 scopus 로고    scopus 로고
    • Role of cell death-regulating genes in two distinct cell death paradigms of dopaminergic neuronal cell line
    • Oh Y. J., Choi W. S., Oh J. H., O'Malley K. L., Reed J. C. Role of cell death-regulating genes in two distinct cell death paradigms of dopaminergic neuronal cell line. Soc. Neurosci. 23:1997;632.
    • (1997) Soc. Neurosci. , vol.23 , pp. 632
    • Oh, Y.J.1    Choi, W.S.2    Oh, J.H.3    O'Malley, K.L.4    Reed, J.C.5
  • 26
    • 0030788276 scopus 로고    scopus 로고
    • Bax accelerates staurosporine-induced but suppresses nigericin-induced neuronal cell death
    • Oh J. H., O'Malley K. L., Krajewski S., Reed J. C., Oh Y. J. Bax accelerates staurosporine-induced but suppresses nigericin-induced neuronal cell death. NeuroReport. 8:1997b;1851-1856.
    • (1997) NeuroReport , vol.8 , pp. 1851-1856
    • Oh, J.H.1    O'Malley, K.L.2    Krajewski, S.3    Reed, J.C.4    Oh, Y.J.5
  • 27
    • 0030829150 scopus 로고    scopus 로고
    • Regions outside of the Bcl-2 homology domains, BH1 and BH2 protect a dopaminergic neuronal cell line from staurosporine-induced cell death
    • Oh Y. J., Uhland-Smith A., Kim J.-E., O'Malley K. L. Regions outside of the Bcl-2 homology domains, BH1 and BH2 protect a dopaminergic neuronal cell line from staurosporine-induced cell death. Mol. Brain Res. 51:1997c;133-142.
    • (1997) Mol. Brain Res. , vol.51 , pp. 133-142
    • Oh, Y.J.1    Uhland-Smith, A.2    Kim, J.-E.3    O'Malley, K.L.4
  • 28
    • 0027496238 scopus 로고
    • A radical hypothesis for neurodegeneration
    • Olanow C. W. A radical hypothesis for neurodegeneration. Trends Neurosci. 16:1993;439-444.
    • (1993) Trends Neurosci. , vol.16 , pp. 439-444
    • Olanow, C.W.1
  • 29
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai Z. N., Milliman C. L., Korsmeyer S. J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 30
    • 0028040019 scopus 로고
    • Bcl-2 and the regulation of programmed cell death
    • Reed J. C. Bcl-2 and the regulation of programmed cell death. J. Cell Biol. 124:1994;1-6.
    • (1994) J. Cell Biol. , vol.124 , pp. 1-6
    • Reed, J.C.1
  • 31
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the Bcl-2 family
    • Reed J. C. Double identity for proteins of the Bcl-2 family. Nature. 387:1997;773-776.
    • (1997) Nature , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 32
    • 0028118846 scopus 로고
    • Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death
    • Shearman M. S., Ragan C. I., Iversen L. L. Inhibition of PC12 cell redox activity is a specific, early indicator of the mechanism of beta-amyloid-mediated cell death. Proc. Natl. Acad. Sci. USA. 91:1994;1470-1474.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1470-1474
    • Shearman, M.S.1    Ragan, C.I.2    Iversen, L.L.3
  • 34
    • 0027504297 scopus 로고
    • Advances in our understanding of the mechanisms of neurotoxicity of MPTP and related compounds
    • Tipton K. F., Singer T. P. Advances in our understanding of the mechanisms of neurotoxicity of MPTP and related compounds. J. Neurochem. 61:1993;1191-1206.
    • (1993) J. Neurochem. , vol.61 , pp. 1191-1206
    • Tipton, K.F.1    Singer, T.P.2
  • 35
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson C. B. Apoptosis in the pathogenesis and treatment of disease. Science. 267:1995;1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 36
    • 0020440918 scopus 로고
    • The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes
    • Thor H., Smith M. T., Hartzell P., Bellomo G., Jewell S. A., Orrenius S. The metabolism of menadione (2-methyl-1,4-naphthoquinone) by isolated hepatocytes. J. Biol. Chem. 257:1982;12419-12425.
    • (1982) J. Biol. Chem. , vol.257 , pp. 12419-12425
    • Thor, H.1    Smith, M.T.2    Hartzell, P.3    Bellomo, G.4    Jewell, S.A.5    Orrenius, S.6
  • 37
    • 0031013141 scopus 로고    scopus 로고
    • Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons
    • Tompkins M. M., Basgall E. J., Zamrini E., Hill W. D. Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons. Am. J. Pathol. 150:1997;119-131.
    • (1997) Am. J. Pathol. , vol.150 , pp. 119-131
    • Tompkins, M.M.1    Basgall, E.J.2    Zamrini, E.3    Hill, W.D.4
  • 38
    • 0028127058 scopus 로고
    • Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis
    • Walkinshaw G., Waters C. M. Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis. Neuroscience. 63:1994;975-987.
    • (1994) Neuroscience , vol.63 , pp. 975-987
    • Walkinshaw, G.1    Waters, C.M.2
  • 39
    • 0030046508 scopus 로고    scopus 로고
    • Life, death, and the pursuit of apoptosis
    • White E. Life, death, and the pursuit of apoptosis. Genes Dev. 10:1996;1-15.
    • (1996) Genes Dev. , vol.10 , pp. 1-15
    • White, E.1
  • 40
    • 0029906828 scopus 로고    scopus 로고
    • Bax-induced cell death may not require interleukin 1b-converting enzyme-like proteases
    • Xiang J., Chao D. T., Korsmeyer S. J. Bax-induced cell death may not require interleukin 1b-converting enzyme-like proteases. Proc. Natl. Acad. Sci. USA. 93:1996;14559-14563.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 14559-14563
    • Xiang, J.1    Chao, D.T.2    Korsmeyer, S.J.3
  • 41
    • 0029899181 scopus 로고    scopus 로고
    • Molecular thanatopsis: A discourse on the Bcl-2 family and cell death
    • Yang E., Korsmeyer S. J. Molecular thanatopsis: a discourse on the Bcl-2 family and cell death. Blood. 88:1996;386-401.
    • (1996) Blood , vol.88 , pp. 386-401
    • Yang, E.1    Korsmeyer, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.