Partial inactivation of the primary motor cortex hand area: Effects on individuated finger movements

Journal of Neuroscience

Volumn 18, Issue 21, 1998, Pages 9038-9054

  Schieber, Marc H ^a,b,c   Poliakov, Andrew V ^a  

^a UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^b UNITY HEALTH SYSTEM   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Cortex; Dexterity; Finger; Individuation; Macaque; Motor; Muscimol; Response time, somatotopy; Weakness

Indexed keywords

MUSCIMOL;

ANIMAL EXPERIMENT; ARTICLE; ASSOCIATION; BRAIN INJURY; BRAIN MAPPING; FINGER; HAND MOVEMENT; HISTOLOGY; MACACA; MOTOR CONTROL; MOTOR COORDINATION; MOTOR CORTEX; MOTOR DYSFUNCTION; NERVE CELL INHIBITION; NONHUMAN; PRIORITY JOURNAL; PYRAMIDAL TRACT; RESPONSE TIME; TASK PERFORMANCE;

EID: 0032211127     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.18-21-09038.1998     Document Type: Article

References (61)

1. Andersen P, Hagan PJ, Phillips CG, Powell TP (1975) Mapping by microstimulation of overlapping projections from area 4 to motor units of the baboon's hand. Proc R Soc Lond B Biol Sci 188:31-36.
2. Ashe J (1997) Force and the motor cortex. Behav Brain Res 86:1-15.
3. Beck CH, Chambers WW (1970) Speed, accuracy, and strength of forelimb movement after unilateral pyramidotomy in rhesus monkeys. J Comp Physiol Psychol 70:1-22.
4. Beevor C (1903a) The Croonian Lectures on muscular movements. New York: MacMillan.
5. Beevor C (1903b) Remarks on paralysis of the movements of the trunk in hemiplegia. New York: MacMillan.
6. Buys EJ, Lemon RN, Mantel GW, Muir RB (1986) Selective facilitation of different hand muscles by single corticospinal neurones in the conscious monkey. J Physiol (Lond) 381:529-549.
7. Chapman CE, Wiesendanger M (1982) Recovery of function following unilteral lesions of the bulbar pyramid in the monkey. Electroencephalogr Clin Neurophysiol 53:374-387.
8. Cheney PD, Fetz EE (1985) Comparable patterns of muscle facilitation evoked by individual corticomotoneuronal (CM) cells and by single intracortical microstimuli in primates: evidence for functional groups of CM cells. J Neurophysiol 53:786-804.
9. DeFelipe J, Conley M, Jones EG (1986) Long-range focal collateralization of axons arising from corticocortical cells in monkey sensory-motor cortex. J Neurosci 6:3749-3766.
10. Donoghue JP, Leibovic S, Sanes JN (1992) Organization of the forelimb area in squirrel monkey motor cortex: representation of digit, wrist, and elbow muscles. Exp Brain Res 89:1-19.
11. Evarts EV (1968) Relation of pyramidal tract activity to force exerted during voluntary movement. J Neurophysiol 31:14-27.
12. Fulton JF, Kennard MA (1932) A study of flaccid and spastic paralyses produced by lesions of the cerebral cortex in primates. Res Publ Assoc Res Nerv Ment Dis 13:158-210.
13. Georgopoulos AP, Ashe J, Smyrnis N, Taira M (1992) The motor cortex and the coding of force. Science 256:1692-1695.
14. Gould III HJ, Cusick CG, Pons TP, Kaas JH (1986) The relationship of corpus callosum connections to electrical stimulation maps of motor, supplementary motor, and the frontal eye fields in owl monkeys. J Comp Neurol 247:297-325.
15. Grafton ST, Woods RP, Mazziotta JC (1993) Within-arm somatotopy in human motor areas determined by positron emission tomography imaging of cerebral blood flow. Exp Brain Res 95:172-176.
16. Hamuy TP (1956) Retention and performance of "skilled movements" after cortical ablations in monkeys. Bull John Hopkins Hosp 98:417-444.
17. Hepp-Reymond MC (1988) Functional organization of motor cortex and its participation in voluntary movements. In: Comparative primate biology (Seklis HD, Erwin J eds), pp 501-624. New York: Alan R. Liss.
18. Hepp-Reymond MC, Wiesendanger M (1972) Unilateral pyramidotomy in monkeys: effect on force and speed of a conditioned precision grip. Brain Res 36:117-131.
19. Hepp-Reymond MC, Wiesendanger M, Brunnert A, Mackel R, Unger C, Wespi, J (1970) Effects of unilateral pyramidotomy on conditioned finger movement in monkey (Macaca irus). Brain Res 24:544.
20. Hepp-Reymond MC, Trouche E, Wiesendanger M (1974) Effects of unilateral and bilateral pyramidotomy on a conditioned rapid precision grip in monkeys (Macaca fascicularis). Exp Brain Res 21:519-527.
21. Hepp-Reymond MC, Wyss UR, Anner R (1978) Neuronal coding of static force in the primate motor cortex. J Physiol Paris 74:287-291.
22. Huffman DS, Strick PL (1995) Effects of a primary motor cortex lesion on step-tracking movements of the wrist. J Neurophysiol 73:891-895.
23. Humphrey DR (1986) Representation of movements and muscles within the primate precentral motor cortex: historical and current perspectives. Fed Proc 45:2687-2699.
24. Humphrey DR, Reed DJ (1983) Separate cortical systems for control of joint movement and joint stiffness: reciprocal activation and coactivation of antagonist muscles. Adv Neurol 39:347-372.
25. Huntley GW, Jones EG (1991) Relationship of intrinsic connections to forelimb movement representations in monkey motor cortex: a correlative anatomic and physiological study. J Neurophysiol 66:390-413.
26. Jacobs KM, Donoghue JP (1991) Reshaping the cortical motor map by unmasking latent intracortical connections. Science 251:944-947.
27. Keller A, Asanuma H (1993) Synaptic relationships involving local axon collaterals of pyramidal neurons in the cat motor cortex. J Comp Neurol 336:229-242.
28. Kleinschmidt A, Nitschke MF, Frahm J (1997) Somatotopy in the human motor cortex hand area. A high-resolution functional MRI study. Eur J Neurosci 9:2178-2186.
29. Kubota K (1996) Motor cortical muscimol injection disrupts forelimb movement in freely moving monkeys. NeuroReport 7:2379-2384.
30. Kwan HC, MacKay WA, Murphy JT, Wong YC (1978) Spatial organization of precentral cortex in awake primates. II. Motor outputs. J Neurophysiol 41:1120-1131.
31. Laursen AM (1977) Task dependence of slowing after pyramidal lesions in monkeys. J Comp Physiol Psychol 91:897-906.
32. Lawrence DG, Kuypers HG (1968) The functional organization of the motor system in the monkey. I. The effects of bilateral pyramidal lesions. Brain 91:1-14.
33. Martin JH (1991) Autoradiographic estimation of the extent of reversible inactivation produced by microinjection of lidocaine and muscimol in the rat. Neurosci Lett 127:160-164.
34. Martin JH, Ghez C (1993) Differential impairments in reaching and grasping produced by local inactivation within the forelimb representation of the motor cortex in the cat. Exp Brain Res 94:429-443.
35. Martin JH, Cooper SE, Ghez C (1993) Differential effects of local inac-tivation within motor cortex and red nucleus on performance of an elbow task in the cat. Exp Brain Res 94:418-428.
36. Mewes K, Cheney PD (1991) Facilitation and suppression of wrist and digit muscles from single rubromotoneuronal cells in the awake monkey. J Neurophysiol 66:1965-1977.
37. Nudo RJ, Milliken GW (1996) Reorganization of movement representations in primary motor cortex following focal ischemic infarcts in adult squirrel monkeys. J Neurophysiol 75:2144-2149.
38. Nudo RJ, Wise BM, Sifuentes F, Milliken GW (1996) Neural substrates for the effects of rehabilitative training on motor recovery after ischemic infarct. Science 272:1791-1794.
39. Passingham RE, Perry VH, Wilkinson F (1983) The long-term effects of removal of sensorimotor cortex in infant and adult rhesus monkeys. Brain 106:675-705.
40. Penfield W, Boldrey E (1937) Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain 37:389-443.
41. Penfield W, Rasmussen T (1950) The cerebral cortex of man. New York: MacMillan.
42. Porter R, Lemon RN (1993) Corticospinal function and voluntary movement. Oxford: Clarendon.
43. Preuss TM, Stepniewska I, Jain N, Kaas JH (1997) Multiple divisions of macaque precentral motor cortex identified with neurofilament antibody SMI-32. Brain Res 767:148-153.
44. Rouiller EM, Yu XH, Tempini A (1997) Effect of inactivation of the hand representation of the primary and supplementary motor cortical areas on precision grip performance in monkeys. In: Perspectives of motor behavior and its neural basis (Hepp-Reymond MC, Marini G, eds), pp 33-43. New York: Karger.
45. Sanes JN, Donoghue JP, Thangaraj V, Edelman RR, Warach S (1995) Shared neural substrates controlling hand movements in human motor cortex. Science 268:1775-1777.
46. Sato KC, Tanji J (1989) Digit-muscle responses evoked from multiple intracortical foci in monkey precentral motor cortex. J Neurophysiol 62:959-970.
47. Schieber MH (1990) How might the motor cortex individuate movements? Trends Neurosci 13:440-445.
48. Schieber M H (1991) Individuated finger movements of rhesus monkeys: a means of quantifying the independence of the digits. J Neurophysiol 65:1381-1391.
49. Schieber M H (1995) Muscular production of individuated finger movements: the roles of extrinsic finger muscles. J Neurosci 15:284-297.
50. Schieber M H, Hibbard LS (1993) How somatotopic is the motor cortex hand area? Science 261:489-492.
51. Schwartzman RJ (1978) A behavioral analysis of complete unilateral section of the pyramidal tract at the medullary level in Macaca mulatta. Ann Neurol 4:234-244.
52. Shinoda Y, Yokota J, Futami T (1981) Divergent projection of individual corticospinal axons to motoneurons of multiple muscles in the monkey. Neurosci Lett 23:7-12.
53. Smith AM, Hepp-Reymond MC, Wyss UR (1975) Relation of activity in precentral cortical neurons to force and rate of force change during isometric contractions of finger muscles. Exp Brain Res 23:315-332.
54. Soechting JF, Flanders M (1997) Flexibility and repeatability of finger movements during typing: analysis of multiple degrees of freedom. J Comp Neurosci 4:29-46.
55. Strick PL, Preston JB (1978) Multiple representation in the primate motor cortex. Brain Res 154:366-370.
56. Tower SS (1940) Pyramidal lesion in the monkey. Brain 63:36-90.
57. Travis AM (1955) Neurological deficiencies after ablation of the precentral motor area in Macaca mulatta. Brain 78:155-173.
58. Woolsey CN, Settlage PH, Meyer DR, Sencer W, Hamuy TP, Travis AM (1951) Patterns of localization in precentral and "supplementary" motor areas and their relation to the concept of a premotor area. Res Publ Assoc Res Nerv Ment Dis 30:238-264.
59. Woolsey CN, Gorska T, Wetzel A, Erickson TC, Earls FJ, Allman JM (1972) Complete unilateral section of the pyramidal tract at the medullary level in Macaca mulatta. Brain Res 40:119-123.
60. Woolsey CN, Erickson TC, Gilson WE (1979) Localization in somatic sensory and motor areas of human cerebral cortex as determined by direct recording of evoked potentials and electrical stimulation. J Neurosurg 51:476-506.
61. Ziemann U, Rothwell JC, Ridding MC (1996) Interaction between intracortical inhibition and facilitation in human motor cortex. J Physiol (Lond) 496:873-881.