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note
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Estimates of coverage are based on an analysis of the phase contrast images for several different samples and sample locations, using both the magnitude and contour of the topology as diagnostics for discriminating the signal from the background noise. The images used for this analysis were typically hundreds of micrometers in size. The limiting turnover rate for the oxidase was then computed using this approximate coverage and the rate data are shown and discussed in detail in Figure 2 of ref 7.
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