Conceptual design of a californium-based epithermal neutron beam for boron neutron capture therapy using a subcritical multiplying assembly

Nuclear Technology

Volumn 124, Issue 2, 1998, Pages 175-182

  Kim, Do Heon ^a   Kim, Jong Kyung ^a,b,c  

^a Hanyang University   (South Korea)

^b UNIVERSITY AT BUFFALO   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Boron neutron capture therapy; Californium 252; Subcritical multiplying assembly

Indexed keywords

BORON; CALIFORNIUM; COMPUTER SIMULATION; DOSIMETRY; HEALTH RISKS; MONTE CARLO METHODS; NEUTRON SOURCES; NEUTRONS; PARTICLE BEAMS;

BORON NEUTRON CAPTURE THERAPY; NEUTRON BEAMS; SUBCRITICAL MULTIPLYING ASSEMBLY; TUMORS;

RADIOTHERAPY;

EID: 0032202562     PISSN: 00295450     EISSN: None     Source Type: Journal    
DOI: 10.13182/NT98-A2917     Document Type: Article

References (13)

1. R. G. ZAMENHOF, B. W. MURRAY, G. L. BROWNELL, G. R. WELLUM, and E. I. TOLPIN, "Boron Neutron Capture Therapy for the Treatment of Cerebral Gliomas. I: Theoretical Evaluation of the Efficacy of Various Neutron Beams," Med. Phys., 2, 2, 47 (1975).
2. R. M. BRUGGER, G. CONSTANTINE, O. K. MARLING, and F. J. WHEELER, "Rapporteurs' Report," Neutron Beam Design, Development, and Performance for Neutron Capture Therapy, p. 2, O. K. HARLING et al., Eds., Plenum Press, New York (1990).
3. J. C. YANCH, J. K. KIM, and M. J. WILSON, "Design of a Californium-Based Epithermal Neutron Beam for Neutron Capture Therapy," Phys. Med. Biol., 38, 1145 (1993).
4. J. K. KIM, J. C. YANCH, and M. J. WILSON, "Californium-Based Epithermal Neutron Beams for Neutron Capture Therapy," Advances in Neutron Capture Therapy, p. 131, A. H. SOLOWAY et al., Eds., Plenum Press, New York (1993).
5. S. D. CLEMENT, J. R. CHOI, R. G. ZAMENHOF, J. C. YANCH, and O. K. HARLING, "Monte Carlo Methods of Neutron Beam Design for Neutron Capture Therapy at the MIT Research Reactor (MITR-II)," Neutron Beam Design, Development, and Performance for Neutron Capture Therapy, p. 45, O. K. HARLING et al., Eds., Plenum Press, New York (1990).
6. J. C. YANCH, X-L. ZHOU, R. E. SHEFER, and R. E. KLINKOWSTEIN, "Accelerator-Based Epithermal Neutron Beam Design for Neutron Capture Therapy," Med. Phys., 19, 3, 709 (1992).
7. "MCNP - A General Monte Carlo N-Particle Transport Code, Version 4A," LA-12625-M, J. F. BRIESMEISTER, Ed., Los Alamos National Laboratory (1993).
8. J. C. YANCH, X.-L. ZHOU, and G. L. BROWNELL, "A Monte Carlo Investigation of the Dosimetric Properties of Monoenergetic Neutron Beams for Neutron Capture Therapy," Radiat. Res., 126, 1 (1991).
9. W. S. SNYDER, M. R. FORD, G. G. WARNER, and H. L. FISHER, Jr., "Estimates of Absorbed Fractions for Monoenergetic Photon Sources Uniformly Distributed in Various Organs of a Heterogeneous Phantom," MIRD, J. Nucl. Med., Suppl. No. 3, Pamphlet 5 (1969).
10. O. L. DEUTSCH and B. W. MURRAY, "Monte Carlo Dosimetry Calculation for Boron Neutron-Capture Therapy in the Treatment of Brain Tumors," Nucl. Technol., 26, 320 (1975).
11. R. S. CASWELL, J. J. COYNE, and M. L. RANDOLPH, "Kerma Factors of Elements and Compounds for Neutron Energies Below 30 MeV," Int. J. Appl. Radiat. Isot., 33, 1227 (1982).
12. J. A. CODERRE, D. N. SLATKIN, P. L. MICCA, and J. R. CIALLELLE, "Boron Neutron Capture Therapy of a Murine Melanoma with p-boronophenylalanine: Dose Response Analysis Using a Morbidity Index," Radiat. Res., 128, 177 (1991).
13. 252Cf Neutron Therapy, Lexington, Kentucky, May 1990.