Association of hepatic nuclear factor-4 in the apolipoprotein B promoter: A preliminary report

Brazilian Journal of Medical and Biological Research

Volumn 31, Issue 11, 1998, Pages 1405-1408

  Novak E M ^a   Dantas, K C ^a   Charbel, C E ^a   Bydlowski, S P ^a,b  

^a FUNDAÇÃO PRÓ SANGUE HEMOCENTRO DE SÃO PAULO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Apolipoprotein B promoter; C EBP ; HNF 4

Indexed keywords

APOLIPOPROTEIN B; OLIGONUCLEOTIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

NUCLEOTIDE SEQUENCE; PROMOTER REGION; REVIEW;

APOLIPOPROTEINS B; BASE SEQUENCE; OLIGONUCLEOTIDES; PROMOTER REGIONS (GENETICS); TRANSCRIPTION FACTOR AP-1; TRANSCRIPTION FACTORS;

EID: 0032200830     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X1998001100006     Document Type: Article

References (15)

1. Goldstein JL & Brown MS (1977). The low density lipoprotein pathway and its relation to atherosclerosis. Annual Review of Biochemistry, 46: 879-930.
2. Brown MS & Goldstein JL (1986). A receptor-mediated pathway for cholesterol homeostasis. Science, 232: 34-47.
3. Cladaras C, Hadzoupoulou-Cladaras M, Avila R, Nussbaum A, Nicosi R & Zannis VI (1986). Complementary DNA derived structure of the amino terminal domain of human apolipoprotein B and size of its messenger RNA transcript. Biochemistry, 25: 5351-5357.
4. Demmer LA, Levin MS, Elovson J, Reuben MA, Lusis AJ & Gordon JI (1986). Tissue-specific expression and development regulation of the rat apolipoprotein B gene. Proceedings of the National Academy of Sciences, USA, 83: 8102-8106.
5. Kardassis D, Zannis V & Cladaras C (1992). Organization of the regulatory elements and nuclear activities participating in the transcription of the human apolipoprotein B gene. Journal of Biological Chemistry, 267: 2622-2632.
6. Metzer S, Hallaas JL, Bresiow JL & Sladek FM (1993). Orphan receptor HNF-4 and bZip protein C/EBPα bind to overlapping regions of the apolipoprotein B gene promoter and synergistically activate transcription. Journal of Biological Chemistry, 286: 16831-16838.
7. Sladek FM, Zhong W, Lai E & Darnell Jr JE (1990). Liver enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. Genes and Development, 23: 2353-2365.
8. Landschulz WH, Johnson PF & McKnight S (1988). The leucine zipper: A hypothetical structure common to a new class of DNA binding proteins. Science, 240: 1759-1764.
9. Kadonaga JT & Tijan J (1986). Affinity purification of sequence-specific DNA binding proteins. Proceedings of the National Academy of Sciences, USA, 83: 5889-5893.
10. Kardassis D, Zannis V & Cladaras C (1990). Purification and characterization of the nuclear factor BA1. A transcriptional activator of the human apoB gene. Journal of Biological Chemistry, 265: 21733-21740.
11. Novak EM & Bydlowski P (1997). NFY transcription factor binds to regulatory element AIC and transactivates the human apolipoprotein A-I promoter in HepG2 cells. Biochemical and Biophysical Research Communications, 231: 140-143.
12. Giese K, Cox J & Grosschedl R (1992). The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures. Cell, 69: 185-195.
13. Erie G, Yang HC, Schultz C & Bustamante C (1994). DNA bending by Cro protein in specific and nonspecific complexes: implications for protein site recognition and specificity. Science, 266: 1449-2062.
14. Parekh B & Hatfield W (1996). Transcriptional activation by protein-induced DNA bending: Evidence for a DNA structural transmission model. Proceedings of the National Academy of Sciences, USA, 93: 1173-1177.
15. Potthoff SJ, Lorene ER & Nardulli AM (1996). Effects of wild type and mutant estrogen receptors on DNA flexibility, DNA bending, and transcription activation. Molecular Endocrinology, 10: 1095-1105.